Results 91 to 100 of about 52,359 (306)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Diagnostic competences of mathematics teachers - Processes and re-sources

, 2014
https://www.pmena.org/pmenaproceedings/PMENA%2036%20PME%2038%202014%20Proceedings%20Vol%201 ...
Philipp, Kathleen, Leuders, Timo
core  

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Gestion des risques et exportation des PME québécoises vers les pays asiatiques

, 2015
International audienceAu cours des dernières années, les PME des pays développés ont été confrontées à une concurrence de plus en plus vive sur leurs marchés locaux, ce qui a mis en danger la survie de plusieurs d'entre elles.
St-Pierre, Josée, Defays, Lucile, Lacoursière, Richard   +2 more
core   +1 more source

Progressive myoclonus epilepsy in Down syndrome with Alzheimer's disease: An 11‐year longitudinal study and proposed diagnostic red flags

Epilepsia Open, EarlyView.
Abstract Objective Individuals with Down syndrome (DS) face an ultra‐high risk of Alzheimer's disease (AD). Within this continuum, Progressive Myoclonus Epilepsy (PME) has emerged as a marker of advanced neurodegeneration. Building on our 2014 characterization of this syndrome, we aimed to define its long‐term natural history and pathological substrate.
Giuseppe d'Orsi, Ezio Calò, Maria Teresa Di Claudio, Carmela Pia Ferro, Umberto Costantino, Elio Perrone, Raffaela Rita Latino   +6 more
wiley   +1 more source

Innovation de produits et performance : une étude exploratoire de la situation des PME canadiennes

, 2004
International audienceDans le nouvel environnement global dominé par l'accélération des changements technologiques, les exigences accrues des clients, la réduction de la durée de vie des produits et une offre de biens et services plus étendue, l ...
St-Pierre, Josée, Mathieu, Claude
core   +1 more source

Smart Nanodelivery Systems for Immunometabolic Modulation in Osteoarthritis

Exploration, EarlyView.
Smart nanodelivery systems deliver therapeutic payloads across the cartilage matrix to ensure their sustained accumulation within chondrocytes at sites of injury. By targeting specific molecular targets and signaling pathways, these platforms modulate the pathological synovium‐cartilage axis to restore immunometabolic homeostasis and drive tissue ...
Qirui Zhao, Zhewen Mi, Shuya Liu, Shijun Liang, Linjia Peng, Zixuan Gao, Jiaming Li, Xiaoqing Lu, Zhiguang Ren, Yongjie Wan, Shengsheng Cui, Longlong Lu, Xiaoyang Gao, Tao Wang, Hui Liang, Furong Tian, de la Fuente Jesus M, Chong Xiang, Luyi Sun, Lichen Xiang, Daxiang Cui   +20 more
wiley   +1 more source

Teachers researching with university academics

, 2009
This Working Session (WS) was the culmination of a process that started in 2007, as a follow-up to a Research Forum at PME 30. At PME 31, a framework was developed for analysing ways in which university academics and teachers might conduct research ...
Brown, LC, Novotna, J., Goos, M, Goos, M., Brown, L., Novotna, J   +5 more
core  

Research progress on flexible MXene‐based materials in advanced energy storage devices: From preparation strategies to device applications

FlexMat, EarlyView.
This review summarizes MXene synthesis and flexible electrode fabrication for FESDs, highlighting their potential owing to high conductivity and flexibility, and outlines future research directions. Abstract The rapid development of wearable and portable electronics has created demand for flexible energy storage systems (FESDs) that not only exhibit ...
Nanxi Miao, Ying Lu, Xing Gao, Lingzi Pan, Meng Gao, Chenxi Zhang, Ming Liu, Shizhong Wang, Zhongyu Weng, Huan Pang, Huijie Zhou   +10 more
wiley   +1 more source

Oral administration of probiotic spores-based biohybrid system for efficient attenuation of Salmonella Typhimurium-induced colitis

Journal of Nanobiotechnology
Salmonella Typhimurium (S. Tm), a Gram-negative pathogenic bacterium, is one of the most common causes of invasive bacterial diseases. Antibiotic therapy remains the principal therapeutic modality for treating S. Tm infection.
Mengya Niu, Luo Zhao, Shuang Gong, Xinxin Liu, Cuixia Zheng, Jiannan Jiao, Fangfang Wang, Lei Wang   +7 more
doaj   +1 more source