Results 71 to 80 of about 74,938 (343)

Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics

Advanced Science, EarlyView.
Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan, Amir M. Arsh, Vatsala Chauhan, Suchintak Dash, Pooja Ravaria, Andre S. Ribeiro   +5 more
wiley   +1 more source

Mental health and quality of life in patients with premenstrual exacerbation: a cross-sectional study in Japan

Journal of Obstetrics and Gynaecology
Background In the classification of premenstrual disorders (PMDs), premenstrual exacerbation (PME) is listed as one of the variants of PMDs, along with core PMD.
Mariko Ogawa, Yukiko Iioka, Kiyoshi Takamatsu   +2 more
doaj   +1 more source

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

Advanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko, Dongyoon Shin, Junho Park, June Huh, Youngsoo Kim, Jong‐Wan Park   +5 more
wiley   +1 more source

Report of the first PME regional conference: South America

, 2019
From November 14 to 16, 2018, the first PME Regional Conference was held in Rancagua, Chile. The conference was aimed at reaching and gathering South American researchers.
Van Dooren, Wim, Gómez, David Maximiliano   +1 more
core  

AARS2‐SIRT5‐Driven DLD K445 Lactylation Promotes Cuproptosis Resistance in Glioblastoma Stem Cells

Advanced Science, EarlyView.
Lactylation of DLD at K445 by AARS2 suppresses PDH complex activity and reduces DLAT lipoylation, thereby conferring cuproptosis resistance in glioblastoma stem cells. SIRT5‐mediated delactylation restores PDH function and enhances cuproptosis sensitivity.
Mingtian Ding, Haibiao Xu, Cen Liu, Yangyin Ding, Shuai Wang, Jun Yin, Tao Fu, Xiao Jiang, Yuning Chen, Hui Luo, Rui Li, Zhengxin Chen, Huibo Wang   +12 more
wiley   +1 more source

Spatially Confined/Ligand‐Directed Ultrabright NIR‐AIE Nanoprobe for In Vitro Rapid Detection and In Situ Imaging of Bacterial Septic Arthritis

Advanced Science, EarlyView.
Inorganic PbS quantum dots spatially confine AIEgens and enable cooperative luminescence within a ligand‐directed core–shell–shell nanoassembly, generating ultrabright NIR PPANPs with enhanced fluorescence and photothermal performance. The platform enables 10‐min S.
Yujian Li, Jia Shu, Sijia Lv, Leilei Qin, Xuefeng Luo, PengCheng Xiao, Huan Cai, Xin Gao, Yan Zhao, Haotian Zhou, Yaji Yang, Zhenglin Zhu, Shijia Ding, Juan Li, Rui Chen, Wei Huang   +15 more
wiley   +1 more source

Configurations de capacités stratégiques et performance des PME : une étude exploratoire de l’influence de l’environnement national

, 2012
International audienceConfigurations de capacités stratégiques et performance des PME : une étude exploratoire de l'influence de l'environnement national Résumé L'étude de la performance des PME est un sujet de recherche complexe si l'on admet que ces ...
Sanchez, Ruben,, St-Pierre, Josée, Raymond, Louis   +2 more
core   +1 more source

Adoption des technologies mobiles (Mobile Money et réseaux sociaux), rôle médiateur de la confiance numérique et performance commerciale perçue des PME à Kinshasa: une application du modèle TAM étendu [PDF]

Mouvements et Enjeux Sociaux
Cette étude explore les déterminants de l'adoption des technologies mobiles (mobile money et réseaux sociaux) par les Petites et Moyennes Entreprises (PME) à Kinshasa, en s'appuyant sur une extension du Modèle d'Acceptation de la Technologie (TAM).
Gildas MBUNGU MUANDA
doaj  

Les capacités d'internationalisation des PME: Une étude comparative des PME de service et de fabrication

, 2010
International audienceRéférence : Raymond, L., St-Pierre, J. et Uwizeyemungu, S. (2010, décembre). « Les capacités d'internationalisation des PME : une étude comparative des PME de service et de fabrication », Congrès international iPME, Pau ...
St-Pierre, Josée, Raymond, Louis, Uwizeyemungu, Sylvestre   +2 more
core  

Slipids POPS simulations (versions 1 and 2) 298 K 1.0 nm cut-off with LJ-PME

, 2017
<p>Slipids POPS simulations (298 K, starting structure from the CHARMM-GUI) performed with 1.0 nm cut-offs, PME and LJ-PME. Two different simulations generated with different starting velocities are provided (the files
Thomas Piggot (5343761), Thomas Piggot
core   +1 more source