Results 81 to 90 of about 46,684 (307)

Surgeons’ views on preoperative medical evaluation: a qualitative study

Perioperative Medicine, 2017
Background There is substantial variation in the practice of preoperative medical evaluation (PME) and limited evidence for its benefit, which raises concerns about overuse. Surgeons have a unique role in this multidisciplinary practice. The objective of
Kevin R. Riggs, Zackary D. Berger, Martin A. Makary, Eric B. Bass, Geetanjali Chander   +4 more
doaj   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

L’effet de l’extension de marque sur la marque-mère : Rôle médiateur de l’attitude envers l’extension

Revue Marocaine de Recherche en Management et Marketing, 2016
Ce travail orienté vers une approche exploratoire consiste à partir de trente (30) de dossiers de demande de crédit soumis au SFD PAMECAS et à identifier les variables pouvant influencer de façon significative la décision de
DIOP CHEIKH MBACKE
doaj  

Enabling participatory monitoring and evaluation: Insights for conservation practitioners and organizations

Conservation Science and Practice
Mounting environmental crises and the persistent factors driving them require a reconsideration of conservation approaches. Participatory monitoring and evaluation (PME) is increasingly valued as a way for Indigenous peoples and local community actors to
Amanda Sigouin, Ana Luz Porzecanski, Erin Betley, Nadav Gazit, Peter Lichtenthal, Samantha H. Cheng, Pablo Pacheco, Shauna L. Mahajan   +7 more
doaj   +1 more source

Mental health and quality of life in patients with premenstrual exacerbation: a cross-sectional study in Japan

Journal of Obstetrics and Gynaecology
Background In the classification of premenstrual disorders (PMDs), premenstrual exacerbation (PME) is listed as one of the variants of PMDs, along with core PMD.
Mariko Ogawa, Yukiko Iioka, Kiyoshi Takamatsu   +2 more
doaj   +1 more source

Anti‐Carbamylated Protein Antibodies Stabilize Carbamylated Histone H3 to Promote Synovial Activation and Neutrophil Extracellular Trap‐Mediated Bone Loss in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo, Norio Hanata, Eduardo Patino‐Martinez, Ronald Holewinski, Ana Barrera‐Vargas, Javier Merayo‐Chalico, Scott A. Coonrod, David A. Fox, Mariana J. Kaplan, Carmelo Carmona‐Rivera   +9 more
wiley   +1 more source

Impact de la taille sur le contenu des tableaux de bord dans les entreprises au Maroc : résultats d’une étude empirique 65

Revue Marocaine de Recherche en Management et Marketing, 2011
À partir des résultats d'une recherche empirique, cet article examine l’impact de la taille sur la différenciation des indicateurs intégrés dans les tableaux de bord de 62 entreprises installées au Maroc. Les résultats de cette recherche montrent que les
Azzouz ELHAMMA
doaj  

New ways to boost molecular dynamics simulations

Journal of Computational Chemistry, 2015
We describe a set of algorithms that allow to simulate dihydrofolate reductase (DHFR, a common benchmark) with the AMBER all‐atom force field at 160 nanoseconds/day on a single Intel Core i7 5960X CPU (no graphics processing unit (GPU), 23,786 atoms ...
E. Krieger, G. Vriend
semanticscholar   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Impact of the pancreatic enzyme replacement therapy (PERT) shortage on prescribing in England: Analysis of national data

British Journal of Clinical Pharmacology, EarlyView.
Aim Pancreatic enzyme replacement therapy (PERT) is essential for the management of pancreatic exocrine insufficiency. Since June 2023, the United Kingdom has been affected by a global shortage of PERT. We investigated the impact of this shortage on national prescribing trends for Creon, Nutrizym, Pancrex and Pangrol.
Teena S. Varghese, Mary E. Phillips, Louis Fisher, Helen Fitt, Adam Frampton, Christopher Wood, Agnieszka Lemanska   +6 more
wiley   +1 more source