Results 201 to 210 of about 49,900 (290)

Radiotherapy and Immune System Interactions Historical Perspectives and Clinical Advancements

Molecular Carcinogenesis, Volume 65, Issue 6, Page 649-664, June 2026.
ABSTRACT Radiotherapy (RT) has evolved significantly since its inception from treating benign conditions to becoming a cornerstone of cancer treatment. This review examines the complex interactions between RT and the immune system, highlighting its diverse effects on various immune cell populations, and exploring emerging strategies to enhance ...
Safiy Yahia, Ayman J. Oweida, Houda Bahig, Daniel Taussky   +3 more
wiley   +1 more source

Preterm birth skews the developmental trajectory of myeloid-derived suppressor cells in the first 48 hours of life: single-cell transcriptomics and inferred intercellular communication. [PDF]

Mol Med
Hernández-Ríos M, Rincon J, Balzano-Nogueira L, Polcz V, Wang D, Wiggins W, Rodhouse C, Yoham A, Xiao F, Ungaro R, Dirain M, Moldawer L, Maile R, Cai G, Efron P, Larson S.   +15 more
europepmc   +1 more source

Current Status of Kidney Xenotransplantation in Basic Research

Organ Medicine, Volume 3, Issue 2, Page 87-101, June 2026.
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley   +1 more source

Development and Qualification of a Pseudotyped Virus-Based Microneutralisation Assay for Influenza D Virus. [PDF]

Influenza Other Respir Viruses
Marotta MG, Mapulanga T, Maina M, Daly J, Camero M, Diemen PM, Everett HE, Montomoli E, da Costa K, Temperton N, Trombetta CM.   +10 more
europepmc   +1 more source

Strategic positioning and accelerating regulatory clearance for new ventures

Strategic Management Journal, Volume 47, Issue 6, Page 1730-1763, June 2026.
Abstract Research Summary How do new ventures strategically position their products to accelerate regulatory clearance? We investigate this question in the medical device industry, where regulatory clearance is a prerequisite for market entry. We examine 239 new firms' 510(k) device clearances by the FDA between 2001 and 2019.
Emily Cox Pahnke, Tiona Zuzul, Michael Howard   +2 more
wiley   +1 more source

Diagnostic accuracy of serum and synovial biomarker thresholds for diagnosing periprosthetic joint infection: a QUADAS-C-guided systematic review and meta-analysis. [PDF]

Arthroplasty
Sartori M, Brogini S, Contartese D, Rosa F, Lo Presti M, Neri MP, Romagnoli M, Dallari D, Toscano A, Zaffagnini S, Fini M, Giavaresi G.   +11 more
europepmc   +1 more source

Hippocampal subfield differences in people with and without recreational ketamine use: Insights from multi‐modal neuroimaging

Addiction, Volume 121, Issue 6, Page 1541-1556, June 2026.
Abstract Background and aims Recreational ketamine use has increased globally and is associated with psychiatric and cognitive concerns. The hippocampus in preclinical models shows damage and working‐memory disruption with repeated dosing. However, whether specific hippocampal subregions may differ in people with chronic ketamine use remains unclear ...
Yi‐Hsuan Liu, Chia‐Chun Hung, Marc N. Potenza, Kun‐Hsien Chou, Pei‐Lin Lee, Chu‐Chung Huang, Chiang‐Shan R. Li, Tony Szu‐Hsien Lee, Ching‐Po Lin   +8 more
wiley   +1 more source

Potentiation of a Porous Silicon Therapeutic Vaccine in Colorectal Cancer via Oxaliplatin-Mediated Regulation of Myeloid-Driven Immunosuppression. [PDF]

J Funct Biomater
Liu Y, Akay Hacan B, Zheng J, Ge X, Yu D, Chen Z, Xu Y, Shao N, Shen H, Liu X, Pettigrew RI, Pan PY, Chen SH, Mai J.   +13 more
europepmc   +1 more source

Disordered Bile Acid Metabolism in Alcohol‐Related Hepatitis

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 12, Page 1658-1672, June 2026.
Serum conjugated primary bile acids accumulate in alcohol‐related hepatitis due to downregulation of hepatocyte bile acid transporters. Hepatocyte growth factor is elevated in alcohol‐related hepatitis and downregulates BSEP expression. This detrimentally affects the hepatoprotective adaptive reduction in NTCP/increase in BSEP seen in cholestasis ...
Luke D. Tyson, Stephen Atkinson, Benjamin H. Mullish, Alexandros Pechlivanis, Michael Allison, Andrew Austin, Katie Chappell, Stuart J. Forbes, Ewan H. Forrest, Alastair M. Kilpatrick, Tong Liu, Laura Martinez‐Gili, Steven Masson, Mark J. W. McPhail, Joao Nunes, Paul Richardson, Daniel Rodrigo‐Torres, Stephen D. Ryder, Mark Wright, Vishal C. Patel, Nikhil Vergis, Elaine Holmes, Mark R. Thursz   +22 more
wiley   +1 more source

Systematic Evaluation of Physicochemical Properties of PEGylated Gold Nanorods Reveals Cell-Specific Uptake Determinants in Human Immune Cell Subsets. [PDF]

Small Sci
Roy Chaudhuri T, Giesler H, Kovacevic Sarmiento M, Lamers K, Hechler M, Erkelenz M, Haferkamp M, Schirrmann R, Nachev M, Bosnjakovic R, Sures B, Schlücker S, Brandau S.   +12 more
europepmc   +1 more source