Results 11 to 20 of about 517 (110)

Transcriptome Analysis of ‘Kyoho’ Grapevine Leaves Identifies Heat Response Genes Involved in the Transcriptional Regulation of Photosynthesis and Abscisic Acid

Agronomy, 2022
Grapevine is a popular cultivated fruit throughout the world and heat stress is one of the most serious threats to viticulture. However, transcriptional responses, such as molecular properties of photosynthesis and abscisic acid biosynthesis, metabolism ...
Rongrong Guo, Ling Lin, Guiyuan Huang, Xiaofang Shi, Rongfu Wei, Jiayu Han, Sihong Zhou, Ying Zhang, Taili Xie, Xianjin Bai, Xiongjun Cao   +10 more
doaj   +2 more sources

Genes of the de novo and salvage biosynthesis pathways of vitamin B6 are regulated under oxidative stress in the plant pathogen Rhizoctonia solani

Frontiers in Microbiology, 2016
B6 is recognized as an important cofactor required for numerous metabolic enzymes, and has been shown to act as an antioxidant and play a role in stress responses. It can be synthesized through two different routes: salvage and de novo pathways. However,
Jamil eSamsatly, Rony eChamoun, Emile eGluck-Thaler, Suha eJabaji   +3 more
doaj   +2 more sources

Polynucleotides HPT for Asian Skin Regeneration and Rejuvenation [PDF]

Clinical, Cosmetic and Investigational Dermatology
Ting Song Lim,1 ShaoRong Liew,1 Xiang Jie Tee,1 Ian Chong,1 Fui Jun Lo,1 Meng Jun Ho,1 KuokTjun Ong,1 Maurizio Cavallini2 1Clique Clinic, Petaling Jaya, Selangor, Malaysia; 2Dermatology and Dermatosurgery Department, CDI Centro Diagnostico Italiano ...
Lim TS, Liew S, Tee XJ, Chong I, Lo FJ, Ho MJ, Ong K, Cavallini M   +7 more
doaj   +2 more sources

Prospective Multicentre Real-World Study of a Bioregenerative Combination Therapy with Polynucleotide High-Purification Technology (PN HPT™) and Hyaluronic Acid for Moderate-to-Severe Atrophic Facial Acne Scars

Cosmetics
Background: Facial atrophic acne scars have a significant impact on patients’ psychosocial well-being and remain a therapeutic challenge. Existing treatments options are frequently limited by modest efficacy and adverse effects.
Ting Song Lim, Chong Ian, Nurul Ain Abdullah, Tristan Tan, Kuok Tjun Ong, Leda Moro, Maria Tomat, Carmen De Luca, Simona Piscopo, Carolina Prussia, Carlotta Bortoletti   +10 more
doaj   +2 more sources

Polynucleotides Suppress Inflammation and Stimulate Matrix Synthesis in an In Vitro Cell-Based Osteoarthritis Model. [PDF]

Int J Mol Sci, 2023
Osteoarthritis (OA) is characterized by degeneration of the joint cartilage, inflammation, and a change in the chondrocyte phenotype. Inflammation also promotes cell hypertrophy in human articular chondrocytes (HC-a) by activating the NF-κB pathway.
Kuppa SS, Kim HK, Kang JY, Lee SC, Yang HY, Sankaranarayanan J, Seon JK.   +6 more
europepmc   +2 more sources

A Real-Life Assessment of Injectable Polynucleotides High Purification Technology in Aesthetic Medicine for Skin Rejuvenation. [PDF]

J Cosmet Dermatol
ABSTRACT Background Polynucleotides (PN) are innovative polymers that improve skin hydration and elasticity, serving as alternatives to traditional dermal fillers. Medical devices based on PN High Purification Technology (PN HPT) represent a new generation of injectable products designed to restore hydration, elasticity, and overall tissue quality.
Eliana L, Anna P, Stefania B, Concetta S, Luisa C, Agnieszka D, Andrea B, Laura B, Carolina P, Simone S.   +9 more
europepmc   +2 more sources

Prospective Observational Study of Polynucleotide Injections for Periorbital Rhytides. [PDF]

J Cosmet Dermatol
ABSTRACT Introduction Polynucleotides (PN), derived from salmon sperm DNA, are highly purified DNA fragments with reported tissue‐repair and anti‐inflammatory properties mediated through adenosine A2A receptor activation. These agents have been increasingly used in aesthetic dermatology for skin rejuvenation and scar treatment.
Ziade G, Keyrouz E, El Maalouf J, Swaidan D, Karam D, Daou D, Fidawi G.   +6 more
europepmc   +2 more sources

The promising potential of polynucleotide injections for knee osteoarthritis: A systematic review of literature and meta-analysis of randomized control trials. [PDF]

J Exp Orthop
Abstract Purpose The present study aims to synthesize and evaluate the evidence on the effectiveness of intra‐articular polynucleotides (PNs) for knee osteoarthritis (OA). Methods In March 2024, we searched MEDLINE, Emcare, Web of Science and Cochrane Library for studies involving PNs for knee OA in human subjects. Inclusion criteria consisted of human
Elphingstone J, Bowler M, Conte P, Anzillotti G, Kon E.   +4 more
europepmc   +2 more sources

Reduced Descending Itch Inhibition in Peripheral Neuropathy Patients With Chronic Pruritus. [PDF]

Eur J Pain
ABSTRACT Background Peripheral neuropathies (PNP) cause a wide range of symptoms of which pruritus and pain are a major burden to patients. Clarifying their mechanisms will facilitate the adequate symptom management. In contrast to neuropathic pain, neuropathic pruritus has long been understudied.
Eck J, Bigalke S, Schmelz M, Rosenberger DC, Pradier B, Rutsch F, Sommer C, Birklein F, Segelcke D, Pogatzki-Zahn E.   +9 more
europepmc   +2 more sources

Acute intermittent hypoxia in neonatal rodent central nervous system facilitates respiratory frequency through the recruitment of hypothalamic areas. [PDF]

Exp Physiol
Abstract Moderate and acute intermittent hypoxia (IH) facilitates respiration in adults, mostly by recruiting peripheral chemo‐/baroreceptors. As central chemoreceptors are widely expressed in immature brains, we hypothesized that IH modulates respiration at birth through a purely neurogenic mechanism involving the hypothalamus.
Apicella R, Mazzone GL, Taccola G.
europepmc   +2 more sources