Results 21 to 30 of about 127,152 (125)

Prospective Observational Study of Polynucleotide Injections for Periorbital Rhytides. [PDF]

J Cosmet Dermatol
ABSTRACT Introduction Polynucleotides (PN), derived from salmon sperm DNA, are highly purified DNA fragments with reported tissue‐repair and anti‐inflammatory properties mediated through adenosine A2A receptor activation. These agents have been increasingly used in aesthetic dermatology for skin rejuvenation and scar treatment.
Ziade G, Keyrouz E, El Maalouf J, Swaidan D, Karam D, Daou D, Fidawi G.   +6 more
europepmc   +2 more sources

Polynucleotides HPT‐Based Dermal Filler for Skin Rejuvenation: A Prospective Clinical Investigation [PDF]

J Cosmet Dermatol
ABSTRACT Background Polynucleotides (PN)‐based dermal fillers are increasingly used for skin rejuvenation due to their biocompatibility and regenerative properties. Aims This study aimed to confirm the efficacy and safety of Plinest (Mastelli) in improving skin hydration of the face, neck, and décolleté over 4 months follow‐up.
Teramo C, Mattioli A, Prussia C.
europepmc   +2 more sources

Randomised, double-blind comparison of a fixed co-formulation of intra-articular polynucleotides and hyaluronic acid versus hyaluronic acid alone in the treatment of knee osteoarthritis: two-year follow-up

BMC Musculoskeletal Disorders, 2021
Background A first-year interim analysis of this two-year study suggested that intra-articular injections of highly purified, natural-origin polynucleotides and hyaluronic acid (HA) as a fixed combination (PNHA) might improve knee function and joint pain
Cesare Stagni, Martina Rocchi, Alessandro Mazzotta, Nicolandrea Del Piccolo, Nicola Rani, Marco Govoni, Leonardo Vivarelli, Francesca Veronesi, Milena Fini, Dante Dallari   +9 more
doaj   +1 more source

Long‐Term Safety of Intradermal Polynucleotides in the Periocular Region: A Retrospective Study [PDF]

J Cosmet Dermatol
ABSTRACT Background The use of polynucleotides (PN) has increased significantly in aesthetic medicine due to their regenerative properties and favorable short‐term safety profile. However, evidence regarding their long‐term safety, particularly in real‐world clinical practice, remains limited.
Miana E.
europepmc   +2 more sources

Reduced Descending Itch Inhibition in Peripheral Neuropathy Patients With Chronic Pruritus. [PDF]

Eur J Pain
ABSTRACT Background Peripheral neuropathies (PNP) cause a wide range of symptoms of which pruritus and pain are a major burden to patients. Clarifying their mechanisms will facilitate the adequate symptom management. In contrast to neuropathic pain, neuropathic pruritus has long been understudied.
Eck J, Bigalke S, Schmelz M, Rosenberger DC, Pradier B, Rutsch F, Sommer C, Birklein F, Segelcke D, Pogatzki-Zahn E.   +9 more
europepmc   +2 more sources

Acute intermittent hypoxia in neonatal rodent central nervous system facilitates respiratory frequency through the recruitment of hypothalamic areas. [PDF]

Exp Physiol
Abstract Moderate and acute intermittent hypoxia (IH) facilitates respiration in adults, mostly by recruiting peripheral chemo‐/baroreceptors. As central chemoreceptors are widely expressed in immature brains, we hypothesized that IH modulates respiration at birth through a purely neurogenic mechanism involving the hypothalamus.
Apicella R, Mazzone GL, Taccola G.
europepmc   +2 more sources

Intradermal "Skin Boosters": Are We Targeting Too Superficially? [PDF]

J Cosmet Dermatol
Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
Lim TS, Lee S, Haykal D, Yi KH.
europepmc   +2 more sources

Genes of the de novo and salvage biosynthesis pathways of vitamin B6 are regulated under oxidative stress in the plant pathogen Rhizoctonia solani

Frontiers in Microbiology, 2016
B6 is recognized as an important cofactor required for numerous metabolic enzymes, and has been shown to act as an antioxidant and play a role in stress responses. It can be synthesized through two different routes: salvage and de novo pathways. However,
Jamil eSamsatly, Rony eChamoun, Emile eGluck-Thaler, Suha eJabaji   +3 more
doaj   +1 more source

HPT design and drawing upgrades [PDF]

, 2003
This item relates to the HPT (High Pressure/High Temperature) apparatus, designed by Professor Mervyn Paterson, Research School of Earth Sciences, Australian National University and Paterson Instruments Pty Ltd, later Australian Scientific Instruments ...
Mervyn Paterson
core   +1 more source

Involvement of the hypothalamic-pituitary-thyroid axis and its interaction with the hypothalamic-pituitary-adrenal axis in the ontogeny of avian thermoregulation: a review [PDF]

, 2008
The emergence of thermoregulation in avian species is a complex matter in which neural as well as hormonal processes are involved. In a previous paper, the neural aspects of primary avian thermoregulation were discussed.
Brand, H., van den, Kemp, B., Bruggeman, V., Debonne, M., Decuypere, E., Baarendse, P.J.J.   +5 more
core   +1 more source