Results 101 to 110 of about 2,353 (181)

A Case of Pulmonary Tuberculosis with Initial PZA Monoresistance Associated with Total Deletion of the <i>pncA </i>Gene

, 2021
Masahiro Kobayashi, Yuya Motoki, Akio Aono, Satoshi Mitarai, Takefumi Saito   +4 more
openalex   +2 more sources

Use of genetic mutations for prediction of resistance to pyrazinamide in M. tuberculosis strains

International Journal of Mycobacteriology, 2015
Pyrazinamide (PZA) is a prodrug that is converted to the active compound pyrazinoic acid by the pyrazinamidase enzyme (encoded by the pncA gene in Mycobacterium tuberculosis) at low pH.
Daniela M Cirillo, Paolo Miotto, Stefan Niemann   +2 more
doaj  

Summary of non-drug resistance associated mutations detected in pncA gene of DNA isolated from direct AFB smears from Ghana, Kenya, Uganda, and Zambia.

, 2020
Mazhgan Rowneki, Naomi Aronson, Peicheng Du, Paige Sachs, Robert J. Blakemore, Soumitesh Chakravorty, Shawn Levy, Angela Jones, Geetika Trivedi, Sheilla Chebore, Dennis Addo, Denis K. Byarugaba, Panganani Njobvu, Frederick Wabwire-Mangen, Bernard Erima, Eric Ramos, Carlton A. Evans, Braden Hale, James D. Mancuso, David Alland   +19 more
openalex   +2 more sources

Study of Mycobacterium bovis genotypes in human and bovine isolates using spoligotyping, MIRUVNTR and RFLP-PCR

International Journal of Mycobacteriology, 2015
Aims and objectives: The aim of this study is to investigate and detect the prevalence of Mycobacterium bovis subtypes (Mycobacterium bovis subtype bovis and Mycobacterium bovis subtype caprae) in humans and compare the genetic diversity of Mycobacterium
Pooyan Khaleghian, Parisa Farnia, Keivan Tadayon, Nader Mosavari, Mohadeseh Mozafari, Zahra Derakhshani Nejad, Rouollah Keshavarz, Shojaat Dashtipour, Mohamad Reza Masjedi, Ali Akbar Vellayati, Rainak Ghaderi, Samed Boroumandfar   +11 more
doaj  

Comparative evaluation of <em>pncA</em> gene, IS6110 and 12.7-Kb fragment based PCR assays for simultaneous detection of Mycobacterium tuberculosis complex (<em>M. tuberculosis</em> and <em>M. bovis</em>) in cultured strains and clinical specimens

, 2022

openalex   +1 more source

Rapid Detection of Mycobacterium tuberculosis and Pyrazinamide Susceptibility Related topncAMutations in Sputum Specimens through an Integrated Gene-to-Protein Function Approach [PDF]

, 2013
Heng Li, Jun Chen, Man Zhou, Xuelei Geng, Junping Yu, Weihua Wang, Xian‐En Zhang, Hongping Wei   +7 more
openalex   +1 more source

Detecting Mutations in the Mycobacterium tuberculosis Pyrazinamidase Gene pncA to Improve Infection Control and Decrease Drug Resistance Rates in Human Immunodeficiency Virus Coinfection [PDF]

, 2016
Matthew Z. Dudley, Patricia Sheen, Robert H. Gilman, Eduardo Ticona, Jon S. Friedland, Daniela E. Kirwan, Luz Caviedes, Richard Rodríguez, Lilia Cabrera, Jorge Coronel, Louis Grandjean, David Moore, Carlton A. Evans, Luz Huaroto, Víctor Chávez-Pérez, Mirko Zimic   +15 more
openalex   +1 more source

Systematic identification of bacterial factors driving Staphylococcus aureus intracellular lifestyle in non-professional phagocytes. [PDF]

Nat Commun
Rodrigues Lopes I, Alcantara LM, Lopez-Bravo M, Liu Y, Larrouy-Maumus G, Lopez D, Mano M, Eulalio A.   +7 more
europepmc   +1 more source

Sequencing of the pncA Gene in Members of the Mycobacterium tuberculosis Complex Has Important Diagnostic Applications: Identification of a Species-Specific pncA Mutation in “ Mycobacterium canettii ” and the Reliable and Rapid Predictor of Pyrazinamide Resistance

, 2006
Ákos Somoskövi, Jillian Dormandy, Linda M. Parsons, Michel Kaswa, Khye Seng Goh, Nalin Rastogi, Max Salfinger   +6 more
openalex   +2 more sources

The impact of CwlM depletion on the susceptibility of Mycobacterium smegmatis to anti-tuberculosis drugs. [PDF]

PLoS One
Yang S, Ren Y, Wu Y, Li X, Liu X, Deng G.   +5 more
europepmc   +1 more source