Results 81 to 90 of about 2,353 (181)

Pyrazinamide Resistance and Mutation Patterns Among Multidrug-Resistant Mycobacterium tuberculosis from Henan Province

open access: yesInfection and Drug Resistance, 2020
Jie Shi, Ruyue Su, Danwei Zheng, Yankun Zhu, Xiaoguang Ma, Shaohua Wang, Hui Li, Dingyong Sun Henan Province Center for Disease Control and Prevention, Zhengzhou, Henan Province, People’s Republic of ChinaCorrespondence: Jie Shi; Dingyong Sun Tel ...
Shi J   +7 more
doaj  

Preparation, Structural, Morphological, Thermal, Mechanical Properties Antibacterial Activity of Polyvinyl Alcohol/Cellulose Nanocrystal/Eryngium planum Extract/Barberry Anthocyanin Smart Film

open access: yesJournal of Food Quality, Volume 2025, Issue 1, 2025.
Indicator nanocomposite films were prepared by 1% anthocyanin, nanocellulose, and aqueous extract of Eryngium planum with 1%, 2%, and 3% concentrations. According to the results of FTIR, new interactions were observed between the components of the film.
Behrouz Dast Peyman   +5 more
wiley   +1 more source

Internal Tissue Expansion Induces Outward Migration of ADSCs From the Subcutaneous Fat Flap to Promote Skin Regeneration of the Expanded Area

open access: yesStem Cells International, Volume 2025, Issue 1, 2025.
Repair of large soft tissue defects by tissue expansion often faces difficulties in skin expansion. Particularly in those who have lost a significant amount of skin and subcutaneous tissue due to total mastectomy, tissue expansion may result in skin breakdown and exposure of the expander.
Haojing Tang   +5 more
wiley   +1 more source

Novel Prodrug Strategies for the Treatment of Tuberculosis

open access: yesChemistry – An Asian Journal, Volume 19, Issue 23, December 2, 2024.
This review summarises the prodrugs that are currently used in tuberculosis treatment regimens. In particular, nitroimidazole prodrugs that are bioactivated by the hypoxic intracellular environment of Mycobacterium tuberculosis are discussed in detail. Abstract The emergence of drug‐resistant strains of Mycobacterium tuberculosis (M.tb), the causative ...
Christine G. Kim   +3 more
wiley   +1 more source

Pyrazinamide resistance in Swedish multidrug-resistant tuberculosis 2003–2013

open access: yesInternational Journal of Mycobacteriology, 2015
Aims and objectives: The aim of this study is to determine the prevalence of pyrazinamide (PZA) resistance among multidrug-resistant Mycobacterium tuberculosis (MDR-TB) strains isolated in Sweden between 2003 and 2013 and to study the correlation between
M Mansjö, J Werngren, S Hoffner
doaj  

Absence of the Genetic Marker IS6110 from a Strain of Mycobacterium tuberculosis Isolated in Ontario

open access: yesCanadian Journal of Infectious Diseases, 1998
A 35-year-old female patient from Waterloo, Ontario was diagnosed with pulmonary tuberculosis in June 1995. Records indicated that the patient had emigrated from Laos circa 1990.
Susan T Howard   +3 more
doaj   +1 more source

Aspartate decarboxylase (PanD) as a new target of pyrazinamide in Mycobacterium tuberculosis

open access: yesEmerging Microbes and Infections, 2014
Pyrazinamide (PZA) is a frontline anti-tuberculosis drug that plays a crucial role in the treatment of both drug-susceptible and multidrug-resistant tuberculosis (MDR-TB). PZA is a prodrug that is converted to its active form, pyrazinoic acid (POA), by a
Wanliang Shi   +7 more
doaj   +1 more source

Mycobacterium tuberculosis: The Mechanism of Pathogenicity, Immune Responses, and Diagnostic Challenges

open access: yesJournal of Clinical Laboratory Analysis, Volume 38, Issue 23, December 2024.
Mycobacterium tuberculosis acts as the causative agent of human tuberculosis and is regarded as one of the most adaptable human pathogens. M. tuberculosis possesses several virulence factors that help the bacterium evade mucous barriers. The infection caused by M.
Noura Mohammadnabi   +8 more
wiley   +1 more source

Mycobacterium tuberculosis isolates from Rio de Janeiro reveal unusually low correlation between pyrazinamide resistance and mutations in the pncA gene

open access: yesInfection, Genetics and Evolution, 2013
It has been widely accepted, that pyrazinamide (PZA) resistance in Mycobacterium tuberculosis is correlated with mutations in the pncA gene. But since years researchers have been puzzled by the fact that up to 30% of PZA resistant strains do not show any correlation between PZA resistance and mutations in the pncA gene, and thus may vary with ...
Bhuju, Sabin   +7 more
openaire   +3 more sources

Hepatocyte‐derived extracellular vesicles regulate liver regeneration through a negative feedback mechanism

open access: yesJournal of Extracellular Biology, Volume 3, Issue 11, November 2024.
Abstract While significant progress has been made in understanding various aspects of liver regeneration, the molecular mechanisms responsible for the initiation and termination of cell proliferation in the liver following massive tissue loss or injury of liver remain unknown.
Mina McGinn   +3 more
wiley   +1 more source

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