Results 51 to 60 of about 46,971 (258)

Elucidating the impact of the pneumococcal conjugate vaccine programme on pneumonia, sepsis and otitis media hospital admissions in England using a composite control

BMC Medicine, 2018
BackgroundThe seven-valent pneumococcal conjugate vaccine (PCV) was introduced in England in September 2006, changing to the 13-valent vaccine in April 2010.
D. Thorrington, N. Andrews, J. Stowe, E. Miller, A. V. van Hoek   +4 more
semanticscholar   +1 more source

Vaccination in dermatology 2025: Update considering current recommendations of the German Standing Committee on Vaccination

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The immunosuppressive and immunomodulatory treatment of dermatological patients necessitates the regular review and updating of standard vaccinations and vaccines indicated for specific conditions. The German Standing Committee on Vaccination (STIKO) at the Robert Koch Institute regularly publishes evidence‐based vaccination recommendations ...
Johanna Stoevesandt, Marc Schmalzing, Sophia Mohme, Matthias Goebeler   +3 more
wiley   +1 more source

Human monoclonal antibodies isolated from a primary pneumococcal conjugate Vaccinee demonstrates the expansion of an antigen-driven Hypermutated memory B cell response

BMC Infectious Diseases, 2018
Background Community-acquired pneumonia is a leading infectious cause of hospitalization. A few vaccines exist to prevent pneumococcal disease in adults, including a pneumococcal polysaccharide unconjugated vaccine and a protein conjugated polysaccharide
Zhifeng Chen, Kara S. Cox, Aimin Tang, Jeanette Roman, Malorie Fink, Robin M. Kaufhold, Liming Guan, Andy Xie, Melissa A. Boddicker, Debra Mcguinness, Xiao Xiao, Hualin Li, Julie M. Skinner, Thorsten Verch, Mary Retzlaff, Kalpit A. Vora   +15 more
doaj   +1 more source

Analysis of pneumococcal serotypes distribution to determine a model composition for a Russian pneumococcal conjugate vaccine

Биопрепараты: Профилактика, диагностика, лечение, 2022
Diseases caused by Streptococcus pneumoniae, as well as antibiotic resistance of its serotypes, are the leading cause of death amongst children worldwide.
V. P. Trukhin, A. E. Evtushenko, E. L. Salimova, A. D. Konon, M. R. Khaitov, V. A. Merkulov   +5 more
doaj   +1 more source

Public health impact of pneumococcal conjugate vaccine infant immunization programs: assessment of invasive pneumococcal disease burden and serotype distribution

Expert Review of Vaccines, 2018
Introduction: Pneumococcal conjugate vaccine (PCV) impact studies have reported substantial reductions in the incidence of invasive pneumococcal disease (IPD) after implementation of childhood PCV programs.
P. Izurieta, Priti Bahety, R. Adegbola, Christopher Clarke, B. Hoet   +4 more
semanticscholar   +1 more source

Vaccination in Multiple Myeloma: Challenges and Strategies

European Journal of Haematology, EarlyView.
ABSTRACT Background Multiple myeloma (MM) is a hematological malignancy characterized by profound immunosuppression resulting from both disease‐related mechanisms and treatment‐induced immune dysfunction. This compromised immune status markedly increases susceptibility to infections, a leading cause of morbidity and mortality in MM patients.
Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Santino Caserta, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

INTERNATIONAL EXPERIENCE WITH 7-VALENT PNEUMOCOCCAL CONJUGATE VACCINE

Педиатрическая фармакология, 2009
The article is devoted to one of the serious problems of the today's medicine — pneumococcal infection. The authors show its importance for public health in terms of its influence upon infant and child mortality and in validization.
David G. McIntosh
doaj   +2 more sources

Outbreak of Serotype 1 Invasive Pneumococcal Disease, Kibera Urban Informal Settlement, Nairobi, Kenya, 2023

Emerging Infectious Diseases
Use of 10-valent pneumococcal conjugate vaccine in Kenya has led to substantial reductions in vaccine-type pneumococcal carriage and invasive pneumococcal disease.
Terry Komo, Patrick K. Munywoki, Maria da Gloria Carvalho, Joshua Auko, Alice Ouma, Allan Audi, George O. Agogo, Daniel Omondi, Arthur Odoyo, Herine Odiembo, Newton Wamola, Mike Osita, Clayton Onyango, Naomi Lucchi, Peninah Munyua, Amy Herman-Roloff, Shanda Larson, Sopio Chochua, Fabiana C. Pimenta, Godfrey Bigogo, Jennifer R. Verani   +20 more
doaj   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

Immunology, EarlyView.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder, Md. Mijanur Rahman, Md. Sifat Rahi, Dean L. Pountney, Ming Q. Wei   +4 more
wiley   +1 more source

The 13-Valent Pneumococcal Conjugate Vaccine Elicits Serological Response and Lasting Protection in Selected Patients With Primary Humoral Immunodeficiency

Frontiers in Immunology, 2021
BackgroundPatients with primary humoral immunodeficiency are more prone to invasive as well as recurrent pneumococcal infections. Therefore, anti-pneumococcal vaccination including the 13-valent conjugate vaccine is recommended. Nevertheless, to date, no
Ailsa Robbins, Ailsa Robbins, Mathilde Bahuaud, Maxime Hentzien, Quentin Maestraggi, Coralie Barbe, Delphine Giusti, Delphine Giusti, Richard Le Naour, Frederic Batteux, Amélie Servettaz, Amélie Servettaz   +11 more
doaj   +1 more source