Results 21 to 30 of about 42,790 (192)

Obesity, leptin and host defence of Streptococcus pneumoniae: the case for more human research

European Respiratory Review, 2022
Pneumococcal pneumonia is the leading cause of community-acquired pneumonia. Obesity is a risk factor for pneumonia. Host factors play a critical role in susceptibility to pulmonary pathogens and outcome from pulmonary infections.
Caz Hales, Laura Burnet, Maureen Coombs, Andrea M. Collins, Daniela M. Ferreira   +4 more
doaj   +1 more source

Serotype Distribution and Antimicrobial Susceptibility Pattern of Streptococcus pneumoniae in COVID-19 Pandemic Era in Brazil

Microorganisms
Despite the introduction of the pneumococcal vaccine, Streptococcus pneumoniae remains a cause of invasive diseases in Brazil. This study provides the distribution of serotypes and antimicrobial susceptibility patterns for pneumococcal isolates before ...
Samanta C. G. Almeida, Ana Paula S. de Lemos, Ana Luiza Bierrenbach, José Cássio de Moraes, Maria Cristina de Cunto Brandileone   +4 more
doaj   +1 more source

Emerging invasive nonvaccine pneumoccocal serotype 25

Annals of Saudi Medicine, 2013
Streptococcus pneumoniae (pneumococcus) is a bacterial pathogen that causes invasive infections, including septicemia and meningitis, as well as noninvasive infections such as community-acquired pneumonia, sinusitis and acute otitis media.
Badria Rashid Al Waili, Suleiman Alola, Esam Albanyan   +2 more
doaj   +1 more source

Modern Approaches to Vaccinal Prevention of a Pneumococcal Infection in Adults Patients with Diabetes Mellitus (Literature Review)

Эпидемиология и вакцинопрофилактика, 2018
At present, pneumococcal infections remain a major cause of morbidity and mortality around the world, being one of the ten leading causes of death worldwide.
J. A. Paramonova, L. B. Postnikova, M. P. Kostinov, A. A. Tarasova, V. A. Pogrebetzkaya   +4 more
doaj   +1 more source

PNEUMOCOCCAL INFECTION IN RUSSIA: EPIDEMIOLOGICAL SITUATION

Педиатрическая фармакология, 2010
The article features an analysis of available literature on the incidence, etiological characteristics, clinical forms of pneumococcal infections in the Russian Federation with a break-down by age group highlighting risk factors. It provides clinical and
I.S. Koroleva, S.M. Kharit, A.A. Ruleva, A.L. Perova, S.V. Sidorenko   +4 more
doaj   +2 more sources

Pathogenesis of pneumococcal infection [PDF]

Journal of Medical Microbiology, 2000
The pathogenesis of pneumococcal infection is a complex interplay between pneumococcal virulence determinants and the host immune response. Molecular studies have considerably advanced our knowledge and understanding of the precise structures and functions of the different determinants and their pathogenic roles. This review describes the mechanisms by
S H, Gillespie, I, Balakrishnan
openaire   +2 more sources

Impact of preceding flu-like illness on the serotype distribution of pneumococcal pneumonia.

PLoS ONE, 2014
BackgroundEven though the pathogenicity and invasiveness of pneumococcus largely depend on capsular types, the impact of serotypes on post-viral pneumococcal pneumonia is unknown.Methods and findingsThis study was performed to evaluate the impact of ...
Joon Young Song, Moon H Nahm, Hee Jin Cheong, Woo Joo Kim   +3 more
doaj   +1 more source

The Saudi Thoracic Society pneumococcal vaccination guidelines-2016

Annals of Thoracic Medicine, 2016
Streptococcus pneumoniae (pneumococcus) is the leading cause of morbidity and mortality worldwide. Saudi Arabia is a host to millions of pilgrims who travel annually from all over the world for Umrah and the Hajj pilgrimages and are at risk of developing
N S Alharbi, A M Al-Barrak, M S Al-Moamary, M O Zeitouni, M M Idrees, M O Al-Ghobain, A A Al-Shimemeri, Mohamed S Al-Hajjaj   +7 more
doaj   +1 more source

Optimal age targeting for pneumococcal vaccination in older adults; a modelling study

Nature Communications, 2023
Vaccination against invasive pneumococcal disease is recommended for older adults but the optimal age group to target has not been determined and may vary by epidemiological setting.
Deus Thindwa, Samuel Clifford, Jackie Kleynhans, Anne von Gottberg, Sibongile Walaza, Susan Meiring, Todd D. Swarthout, Elizabeth Miller, Peter McIntyre, Nick Andrews, Zahin Amin-Chowdhury, Norman Fry, Kondwani C. Jambo, Neil French, Samanta Cristine Grassi Almeida, Shamez N. Ladhani, Robert S. Heyderman, Cheryl Cohen, Maria Cristina de Cunto Brandileone, Stefan Flasche   +19 more
doaj   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source