In vivo Neutralization of Pro-inflammatory Cytokines During Secondary Streptococcus pneumoniae Infection Post Influenza A Virus Infection [PDF]
, 2019 An overt pro-inflammatory immune response is a key factor contributing to lethal pneumococcal infection in an influenza pre-infected host and represents a potential target for therapeutic intervention.
Boehme, Julia D. +8 more
core +1 more source
Pneumonia: Regional experience with prevention programs [PDF]
Терапевтический архив, 2016 Aim. To generalize the regional experience in implementing a package of organizational and methodical and antiepidemic measures for preventing pneumococcal infections. Materials and methods.
A G Chuchalin +7 more
doaj +1 more source
Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]
, 2016 Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST +5 more
core +1 more source
Frontiers in Pharmacology, 2022 Asthmatics are highly susceptible to developing lower respiratory tract infections caused by Streptococcus pneumoniae (SPN, the pneumococcus). It has recently emerged that underlying allergic airway disease creates a lung microenvironment that is ...
Angelica Papanicolaou +9 more
doaj +1 more source
A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]
, 2011 The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Bewley, M.A. +10 more
core +5 more sources
International Journal of Infectious Diseases, 2019 Objectives: The aim of this study was to estimate the impact of antimicrobial resistance (AMR) in secondary pneumococcal pneumonia infections on global mortality during the 2009 influenza pandemic, to estimate future pandemic mortality risk and to inform
Carrie E. Barnes, C. Raina MacIntyre
doaj +1 more source
Coinfection of Leishmania (Viannia) braziliensis and Streptococcus pneumoniae in multiple cutaneous lesions [PDF]
, 2016 Key learning points Cutaneous leishmaniasis is the most common clinical disease caused by all the Leishmania species that are pathogenic to humans. Other bacterial coinfections of Leishmania lesions have been described, but this is the first report of ...
Chiapello, Laura Silvina +6 more
core +2 more sources
Prevention of pneumococcal diseases in the post-seven valent vaccine era: A European perspective
BMC Infectious Diseases, 2012 Background The burden of invasive pneumococcal disease in young children decreased dramatically following introduction of the 7-valent pneumococcal conjugate vaccine (PCV7). The epidemiology of S.
Weil-Olivier Catherine +4 more
doaj +1 more source
BMC Infectious Diseases, 2016 BackgroundIncidence, manifestations and case-fatality rate (CFR) of invasive pneumococcal disease (IPD) vary with age and comorbidities. New vaccines, changing age distribution, prolonged survival among immunocompromised patients and improved sepsis ...
E. Backhaus +7 more
semanticscholar +1 more source
New Vaccines for the Prevention of Pneumococcal Infections
Emerging Infectious Diseases, 1996 Streptococcus pneumoniae is a major cause of acute otitis media, pneumonia, bacteremia, and meningitis. Because in recent years antibiotic-resistant pneumococcal strains have been emerging throughout the world, vaccination against pneumococcal infections
Helena Käyhty, Juhani Eskola
doaj +1 more source