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Clonal expansion within pneumococcal serotype 6C after use of seven-valent vaccine [PDF]
Streptococcus pneumoniae causes invasive infections, primarily at the extremes of life. A seven-valent conjugate vaccine (PCV7) is used to protect against invasive pneumococcal disease in children.
Chan, Jacqueline +10 more
core +24 more sources
Streptococcus pneumoniae infection is the most common cause of high morbidity and mortality among children under 5 years of age, immunocompromised people, and the elderly.
M. V. Savkina +6 more
doaj +1 more source
Summary Streptococcus pneumoniae is a frequent cause of pneumonia and meningitis. This article looks at the pneumococcal vaccine, its uses, efficacy, and adverse effects and how vaccination may be improved. We also look at the role of the new conjugate vaccines.
K L, Hattotuwa, C R, Hind
openaire +2 more sources
Recent progress in pneumococcal protein vaccines
Pneumococcal infections continue to pose a significant global health concern, necessitating the development of effective vaccines. Despite the progress shown by pneumococcal polysaccharide and conjugate vaccines, their limited coverage and the emergence ...
Sha Li +4 more
doaj +1 more source
Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection
Streptococcus pneumoniae is a major pathogen causing pneumonia with over 2 million deaths annually, especially in young children and the elderly. To date, at least 98 different pneumococcal capsular serotypes have been identified. Currently, the vaccines
Malihe Masomian +3 more
doaj +1 more source
Efficacy and effectiveness of extended-valency pneumococcal conjugate vaccines [PDF]
The 7-valent pneumococcal protein conjugate vaccine (PCV7) has been shown to be highly efficacious against invasive pneumococcal diseases and effective against pneumonia and in reducing otitis media. The introduction of PCV7 has resulted in major changes
Hyunju Lee, Eun Hwa Choi, Hoan Jong Lee
doaj +1 more source
Pneumococcal disease is a global public health concern as it affects the young, aged and the immunocompromised. The development of pneumococcal vaccines and their incorporation in the immunization programs has helped to reduce the global burden of ...
Ahmed H. Radhi +4 more
doaj +1 more source
Pneumococcal Choline-Binding Proteins Involved in Virulence as Vaccine Candidates
Streptococcus pneumoniae is a pathogen responsible for millions of deaths worldwide. Currently, the available vaccines for the prevention of S.
Julio Sempere +5 more
doaj +1 more source
The COVID-19 pandemic increased the demand for pneumococcal vaccination in Japan
Although routine vaccinations in children decreased during the coronavirus disease 2019 (COVID-19) pandemic, pneumococcal vaccine coverage in older adults has remained unknown.
Akira Komori +2 more
doaj +1 more source
Adult pneumococcal vaccination – new opportunities
Pneumococcal infections (Streptococcus pneumoniae) remain a significant epidemiological problem globally. Although an invasive pneumo-coccal disease (IPD), which includes meningitis, sepsis and pneumonia with bacteremia, is the most severe form of ...
ERNEST KUCHAR +13 more
doaj +1 more source

