Results 131 to 140 of about 27,990 (228)

Reduced Pathogen‐Specific T Cell Response With BCMA‐Targeted T Cell‐Engaging Therapy to Multiple Myeloma

open access: yeseJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Introduction Bispecific antibody (BsAb) treatment can lead to increased infections in myeloma patients. Methods We used ELISpot and flow cytometry to test the T cell response to BCMA‐CD3‐bispecific T cell engager (BiTE) pavurutamab (PAV) and BCMA‐expressing myeloma cells after in vitro culture.
Ida Steiro   +9 more
wiley   +1 more source

Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management

open access: yesMedComm, Volume 7, Issue 10, October 2026.
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley   +1 more source

Dispensing Patterns of Influenza and Pneumococcal Vaccines in the Private Healthcare Sector in South Africa for 2017 to 2021: A Longitudinal Study

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose The primary aim was to conduct a longitudinal pharmacoepidemiological study on the dispensing patterns of the influenza and pneumococcal vaccines in a section of the private healthcare sector in South Africa in the presence of the COVID‐19 vaccine to document the dispensing of these two respiratory vaccines alongside COVID‐19 vaccines.
I. Truter   +4 more
wiley   +1 more source

Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 10, October 2026.
COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Sasha Raman   +3 more
wiley   +1 more source

Prevalence of nasopharyngeal carriage of pneumococcus by infant age category in a peri urban Nigerian Community.

open access: yes, 2012
Prevalence of nasopharyngeal carriage of pneumococcus by infant age category in a peri urban Nigerian Community.
David Nsekpong (118575)   +7 more
core   +1 more source

Risk Factors of Blood Culture Positivity and Mortality in Bloodstream Infections: A Population‐Based Study of Patients With B‐Cell Malignancies

open access: yesEuropean Journal of Haematology, Volume 117, Issue 4, Page 1061-1071, October 2026.
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen   +7 more
wiley   +1 more source

Subtotal Versus Total Splenectomy in Children With Sickle Cell Disease: Clinical Outcomes and Splenic Function Assessed by Pocked Red Blood Cell Count

open access: yes
American Journal of Hematology, Volume 101, Issue 10, Page 2654-2658, October 2026.
Alma Al Sibaaie   +12 more
wiley   +1 more source

A Machine Learning–Derived Risk Scorecard for Pneumonia Hospitalization in Japanese Old‐Old Adults

open access: yesGeriatrics &Gerontology International, Volume 26, Issue 10, October 2026.
In 1 098 404 community‐dwelling Japanese adults aged ≥ 75 years, a 20‐learner Super Learner using routinely collected health checkup and claims data predicted 1‐year pneumonia hospitalization (test‐set AUC 0.823). An independently developed, well‐calibrated 17‐feature scorecard showed AUC 0.786 and a 15.9‐fold low‐to‐high risk gradient; external ...
Akio Shimizu   +5 more
wiley   +1 more source

Data and R codes associated with the paper "Unraveling the seasonal epidemiology of pneumococcus"

open access: yes, 2019
The zipped folder contains the data and the R codes needed to perform the estimation of the models described in Domenech de Cellès et al., "Unraveling the seasonal epidemiology of pneumococcus ...
Didier Guillemot (69521)   +15 more
core   +1 more source

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