Results 11 to 20 of about 39,365 (191)
Insights into the Interaction between Influenza Virus and Pneumococcus
Jonathan A. McCullers
exaly +2 more sources
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multi‐disciplinary team‐based care. Clinical and insurance claims data were extracted to compare
Tarun Sharma +7 more
wiley +1 more source
ABSTRACT Although living‐donor liver transplantation (LDLT) has become the standard treatment for end‐stage liver disease, one of its major challenges is small‐for‐size syndrome (SFSS). SFSS is characterized by severe icterus and intractable ascites, although the severity of the condition can vary.
Toru Ikegami +6 more
wiley +1 more source
ABSTRACT Iptacopan is a first‐in‐class, oral, selective inhibitor of complement factor B that has demonstrated positive efficacy across several complement‐driven diseases. Here we evaluate the efficacy and safety of iptacopan monotherapy in adult patients with primary immune thrombocytopenia (ITP) and primary cold agglutinin disease (CAD). We performed
Alexander Röth +13 more
wiley +1 more source
The crystal structure of Pneumolysin at 2.0 Å resolution reveals the molecular packing of the pre-pore complex [PDF]
Pneumolysin is a cholesterol-dependent cytolysin (CDC) and virulence factor of Streptococcus pneumoniae. It kills cells by forming pores assembled from oligomeric rings in cholesterol-containing membranes.
Andrew, Peter W +8 more
core +1 more source
In a prospective, randomized study of high‐risk HF patients, simultaneous vaccination against influenza and RSV reduced the risk of the primary composite endpoint (hospitalization for HF, all‐cause death, or infection). The main driver of benefit was a lower incidence of infections.
Jan Biegus +14 more
wiley +1 more source
ABSTRACT Background COVAX was designed to support the discovery, development, and distribution of COVID‐19 vaccines globally, at scale and pace. This article examines how COVAX promoted vaccine equity and what lessons can be learnt. Methods Informed by a scoping review of lessons learnt from GHPs, we reviewed 109 documents related to COVAX and other ...
Charnele Nunes +3 more
wiley +1 more source
Antibody responses to nasopharyngeal carriage of Streptococcus pneumoniae in adults: A longitudinal household study [PDF]
Background. Natural immunity to Streptococcus pneumoniae is thought to be induced by exposure to S. pneumoniae or cross-reactive antigens. No longitudinal studies of carriage of and immune responses to S.
Andrews, N +12 more
core
The manufacture of antibodies in vitro [PDF]
A protein solution with the properties of a specific antiserum to the triphenylmethane dye methyl blue has been made by treating a solution of bovine gamma-globulin and the dye with alkali and then slowly neutralizing the alkali.
Campbell, Dan H., Pauling, Linus
core +2 more sources
Abstract HPV vaccination reduces the risk of developing HPV‐attributable cancers, including cervical cancer. However, an attenuation of HPV vaccine impact after the implementation of HPV vaccination may occur through clinical unmasking. Clinical unmasking is a distinct and complex phenomenon that arises in the absence of clinical interventions ...
Joseph E. Tota +8 more
wiley +1 more source

