Results 71 to 80 of about 49,296 (330)

A low-cost culture- and DNA extraction-free method for the molecular detection of pneumococcal carriage in saliva

open access: yesMicrobiology Spectrum
Molecular methods have improved the sensitivity of the detection of pneumococcal carriage in saliva. However, they typically require sample culture enrichment and nucleic acid extraction prior to performing the detection assay and may limit scalability ...
Chikondi Peno   +10 more
doaj   +1 more source

Investigation into the Causes and Severity of the 1918 Influenza Pandemic [PDF]

open access: yes, 2018
The 1918 Influenza outbreak is regarded as one of the worst pandemics in human history due to its widespread effects across the globe and its high death rate.
Freedenberg, Alex T.
core   +1 more source

THE OCCURRENCE OF PEROXIDE IN CULTURES OF PNEUMOCOCCUS

open access: yesJournal of Experimental Medicine, 1924
1. Conditions which favor the formation and accumulation of peroxide in broth cultures of pneumococcus are free access of air, and the absence of catalase, peroxidase, and other catalysts capable of decomposing this compound.
O. Avery, H. J. Morgan
semanticscholar   +1 more source

Structural Basis of the Membrane Association by the Conserved RocS Membrane‐Targeting Sequence in Streptococcus

open access: yesAdvanced Science, EarlyView.
Chromosome segregation in Streptococcus pneumoniae depends on RocS, a bitopic protein whose membrane‐anchoring mechanisms were unclear. Using NMR and AFM, this study reveals that the widely conserved RocS anchor binds to membranes via a conserved kink‐helix motif which inserts into lipid nanodomains.
Ana Álvarez‐Mena   +11 more
wiley   +1 more source

The manufacture of antibodies in vitro [PDF]

open access: yes, 1942
A protein solution with the properties of a specific antiserum to the triphenylmethane dye methyl blue has been made by treating a solution of bovine gamma-globulin and the dye with alkali and then slowly neutralizing the alkali.
Campbell, Dan H., Pauling, Linus
core   +2 more sources

IMMUNOLOGICAL REACTIONS OF THE ISOLATED CARBOHYDRATE AND PROTEIN OF PNEUMOCOCCUS

open access: yesJournal of Experimental Medicine, 1925
The data presented in this paper clearly indicate that the isolated carbohydrate and nucleoprotein constituents of Pneumococcus differ both serologically and antigenically one from the other.
O. Avery, H. J. Morgan
semanticscholar   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

The interrelationship between phagocytosis, autophagy and formation of neutrophil extracellular traps following infection of human neutrophils by Streptococcus pneumoniae [PDF]

open access: yes, 2017
Neutrophils play an important role in the innate immune response to infection with Streptococcus pneumoniae, the pneumococcus. Pneumococci are phagocytosed by neutrophils and undergo killing after ingestion.
Evans, Tom J.   +2 more
core   +1 more source

Pneumolysin: Pathogenesis and Therapeutic Target

open access: yesFrontiers in Microbiology, 2020
Streptococcus pneumoniae is an opportunistic pathogen responsible for widespread illness and is a major global health issue for children, the elderly, and the immunocompromised population.
Andrew T. Nishimoto   +2 more
doaj   +1 more source

A QUANTITATIVE STUDY OF THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND PURIFIED HOMOLOGOUS ANTIBODY

open access: yesJournal of Experimental Medicine, 1929
1. A quantitative study of the reaction between the soluble specific substance of Type III pneumococcus and its homologous antibody has been made. 2.
M. Heidelberger, F. E. Kendall
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy