Results 61 to 70 of about 19,529 (208)

The role of blinatumomab in adult acute B lymphoblastic leukaemia

British Journal of Haematology, EarlyView.
Blinatumomab, a CD19‐directed bispecific T‐cell engager, has become a crucial part of BCP‐ALL therapy in r/r disease, MRD‐positive disease and has recently been implemented into first‐line therapy of BCP‐ALL. This review discusses important clinical trials with a focus on blinatumomab in first‐line therapy of adult BCP‐ALL.
Anne C. Wilke, Nicola Gökbuget
wiley   +1 more source

Molecular detection of Pneumocystis jirovecii using polymerase chain reaction in immunocompromised patients with pulmonary disorders in northeast of Iran

Current Medical Mycology, 2015
Background and Purpose: Pneumocystis pneumonia, caused by Pneumocystis jirovecii, is a fatal disease threatening patients with AIDS or immunosuppression.
Mahmood Parian, Abdolmajid Fata, Mohammad Javad Najafzadeh, Fariba Rezaeitalab   +3 more
doaj  

pneumonia in a healthy immunocompetent patient: A case report and literature review

SAGE Open Medical Case Reports
Pneumocystis jirovecii pneumonia, typically an opportunistic infection, is commonly associated with risk factors such as low CD4+ lymphocyte count, underlying malignancies, organ transplantation, or immunosuppressive medications.
Houda Rouis, Chirine Moussa, Yoldez Houcine, Ines Zendah, Hamida Kwas, Habib Ghedira, Sonia Maâlej   +6 more
doaj   +1 more source

Seasonal variation of Pneumocystis jirovecii infection: analysis of underlying climatic factors [PDF]

, 2009
Pneumocystis jirovecii causes severe pneumonia (PCP) in immunocompromised patients. Seasonal changes of PCP incidence may be associated with climate changes.
Heesemann, J., Laubender, R.P., Schmoldt, S., Sing, A., Sing, D., Wildner, M.   +5 more
core   +1 more source

Pneumocystis jirovecii Transmission from Immunocompetent Carriers to Infant

Emerging Infectious Diseases, 2008
We report a case of Pneumocystis jirovecii transmission from colonized grandparents to their infant granddaughter. Genotyping of P. jirovecii showed the same genotypes in samples from the infant and her grandparents. These findings support P.
Laura Rivero, Carmen de la Horra, Marco A. Montes-Cano, Alfonso Rodríguez-Herrera, Nieves Respaldiza, Vicente Friaza, Rubén Morilla, Sonia Gutiérrez, José M. Varela, Francisco J. Medrano, Enrique J. Calderón   +10 more
doaj   +1 more source

Point‐of‐Care Testing by Multiplex‐PCR in Different Compartments in Suspected Lower Respiratory Tract Infection After Lung Transplantation—Results of a Prospective Study

Transplant Infectious Disease, EarlyView.
Use of POCtmPCR with noninvasive samples (NPS and sputum) in LTx recipients with viral LRTI are a viable alternative to invasive BAL sampling, ABSTRACT Background Respiratory tract infections (RTIs) are a leading cause of morbidity and mortality following lung transplantation (LTx).
Susanne Simon, Merle Sophie Kaiser, Marcus Bachmann, Gérard Krause, Jens Gottlieb   +4 more
wiley   +1 more source

Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future. [PDF]

, 2017
The respiratory system consists of an integrated network of organs and structures that primarily function for gas exchange. In mammals, oxygen and carbon dioxide are transmitted through a complex respiratory tract, consisting of the nasal passages ...
Miller, Lisa, Pinkerton, Kent, Royer, Christopher, Schelegle, Edward   +3 more
core   +1 more source

The first live term birth following uterus transplantation in Australia

Medical Journal of Australia, EarlyView.
Abstract Objective To report the first live birth following uterus transplantation in Australia. Study design Case report. Setting, participant The first participant in the uterus transplantation research study program at the Royal Hospital for Women, the Prince of Wales Hospital, and Westmead Hospital in Sydney.
Rebecca Deans, Brigitte Gerstl, Antonia W Shand, Sarah Lyons, Aaron Budden, Helen L Barrett, Grant Luxton, Mangalee Fernando, Kenneth Yong, Karen Keung, Kaushalya Arulpragasam, Henry Pleass, King Man Wan, Eva Kehag, Jana‐Emily Pittman, Mianna Lotz, Maria Fenn, Erin Nesbitt‐Hawes, Lily Byun, Katrina Tang, Mats Brannstrom, Jason Abbott   +21 more
wiley   +1 more source

Interhuman Transmission as a Potential Key Parameter for Geographical Variation in the Prevalence of Pneumocystis jirovecii Dihydropteroate Synthase Mutations [PDF]

, 2017
Background. Pneumocystis jirovecii dihydropteroate synthase (DHPS) mutations are associated with failure of prophylaxis with sulfa drugs. This retrospective study sought to better understand the geographical variation in the prevalence of these mutations.
Bille, Jacques, Francioli, Patrick, Hauser, Philippe M., Nahimana, Aimable, Rabodonirina, Meja, Taffe, Patrick, Weber, Rainer   +6 more
core  

Allogeneic Haematopoietic Stem Cell Transplantation Using Reduced‐Intensity Fludarabine, Busulfan and Anti‐T‐Lymphocyte Globulin With Strategic Donor Lymphocyte Infusion in Older Patients With Myeloid Malignancy

European Journal of Haematology, Volume 115, Issue 1, Page 36-45, July 2025.
ABSTRACT Fludarabine, busulfan, and anti‐T‐lymphocyte globulin (FLUBU3+ATLG) reduced‐intensity conditioning is an established preparative regimen for allogeneic haematopoietic stem cell transplantation in older patients with myeloid malignancy. We examined its modern‐day performance in 175 sequentially treated patients on our national programme ...
Chris Armstrong, Eibhlin Conneally, Catherine Flynn, Paul Browne, Mairead Ni Chonghaile, Carmel Ann Galligan, Hayley Foy‐Stones, Nicola Gardiner, Greg Lee, Nina Orfali   +9 more
wiley   +1 more source