Results 61 to 70 of about 15,328 (206)

Toxoplasmosis Beyond Transplantation: Diagnostic and Prevention Challenges in a Patient Receiving Targeted Immunomodulators

Transplant Infectious Disease, EarlyView.
ABSTRACT Toxoplasmosis has long been recognized as a serious complication in immunocompromised host, particularly those with advanced HIV/AIDS, hematopoietic stem‐cell transplantation (HSCT), solid‐organ transplant (SOT), and hematological malignancies. The rapid expansion of targeted immunomodulators, including chimeric antigen receptor T‐cell (CAR‐T)
Joy Mouanes‐Abelin, Christelle Pomares, José G. Montoya, Morgane Pondrom, Lucille DE MARIA, Andrea J. Zimmer, Carlos A. Gomez   +6 more
wiley   +1 more source

Pneumocystis jirovecii infection in patients with acute interstitial pneumonia

, 2020
[ES] Objetivo: La neumonía intersticial aguda (NIA) es una enfermedad grave de etiología desconocida. Pneumocystis jirovecii es un hongo oportunista atípico capaz de colonizar pacientes con enfermedad pulmonar crónica e inducir la activación de los ...
Horra, Carmen de la, Martínez-Risquez M. T., Medrano, Francisco Javier, Friaza Patiño, Vicente, Calderón, Enrique J., Martín-Juan, José   +5 more
core   +1 more source

Differential composition of the pulmonary microbiome in HIV-positive versus HIV-negative patients with Pneumocystis jirovecii.

PLoS ONE
Pneumocystis jirovecii is frequently detected in HIV patients and individuals with compromised immune function. The clinical outcomes of these two groups differ significantly, yet the underlying reasons remain unclear, with limited studies addressing ...
Chang-Run Zhang, Mei Wang, Lei Wang, Li Liu, Yi-Dan Shen, Rui-Fang Chen, Shuai Ren, Wei-Zhong Jin, Hai-Cheng Tang, Qing-Guo Wu   +9 more
doaj   +1 more source

Newly formed cystic lesions for the development of pneumomediastinum in Pneumocystis jirovecii pneumonia

BMC Infectious Diseases, 2009
Background Pneumocystis jirovecii, formerly named Pneumocystis carinii, is one of the most common opportunistic infections in human immunodeficiency virus (HIV)-infected patients.
Yoon Sung, Kwon Yong, Kim Dong-Min, Cho Ju-Yeon, Lee Seung   +4 more
doaj   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6584-6594, August 2026.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Molecular detection of Pneumocystis jirovecii using polymerase chain reaction in immunocompromised patients with pulmonary disorders in northeast of Iran

Current Medical Mycology, 2015
Background and Purpose: Pneumocystis pneumonia, caused by Pneumocystis jirovecii, is a fatal disease threatening patients with AIDS or immunosuppression.
Mahmood Parian, Abdolmajid Fata, Mohammad Javad Najafzadeh, Fariba Rezaeitalab   +3 more
doaj  

Pneumocystis jiroveciiand cystic fibrosis [PDF]

Medical Mycology, 2010
Pneumocystis jirovecii is an atypical opportunistic fungus with lung tropism and worldwide distribution that causes pneumonia in immunosuppressed individuals. The development of sensitive molecular techniques has led to the recognition of a colonization or carrier state of P. jirovecii, in which low levels of the organism are detected in persons who do
Enrique J, Calderón, Vicente, Friaza, Francisco J, Dapena, Carmen, de La Horra   +3 more
openaire   +2 more sources

Pneumocystis jirovecii kann in pseudostratifizierten air-liquid-interface Zellkulturen produktiv gezüchtet werden

, 2014
Although Pneumocystis jirovecii is a well-known and serious pathogen, all previous attempts to isolate, cultivate, and propagate this fungus have failed. This serious challenge in microbiology was addressed in the present study.
Brockmann, M, Soumaya Khalfaoui, Lüsebrink, J, Mai, S, Ramona L. Tillmann, Michael Brockmann, Schildgen, O, Tillmann, RL, Stephanie Mai, Verena Schildgen, Khalfaoui, S, Jessica Lüsebrink, Oliver Schildgen, Monika Pieper, Pieper, M, Schildgen, V   +15 more
core   +1 more source

Coexistência de infeções oportunistas pulmonares num doente com infeção por vírus da imunodeficiência humana e uma forma persistente de pneumonia por Pneumocystis jirovecii: caso clínico

Revista Portuguesa de Pneumologia, 2013
Resumo: Como é sabido, nos doentes com infeção por vírus da imunodeficiência humana (VIH) existe um alto risco de ocorrência de infeções oportunistas (IO), tais como as infeções por Pneumocystis jirovecii, um agente patogénico com distribuição mundial ...
D. Ponces Bento, F. Esteves, O. Matos, A.C. Miranda, F. Ventura, C. Araújo, K. Mansinho   +6 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source