Results 11 to 20 of about 3,561 (170)

Co‐trimoxazole prophylaxis for children who are HIV‐exposed and uninfected: a systematic review

open access: yesJournal of the International AIDS Society, Volume 26, Issue 6, June 2023., 2023
Abstract Introduction Co‐trimoxazole prophylaxis is recommended for children born to women with HIV to protect those who acquire HIV from opportunistic infections, severe bacterial infections and malaria. With scale‐up of maternal antiretroviral therapy, most children remain HIV‐exposed uninfected (HEU) and the benefits of universal co‐trimoxazole are ...
Catherine J. Wedderburn   +6 more
wiley   +1 more source

Chinese expert consensus on the multidisciplinary management of pneumonitis associated with immune checkpoint inhibitor

open access: yesThoracic Cancer, Volume 13, Issue 23, Page 3420-3430, December 2022., 2022
Chinese expert consensus on the multidisciplinary management of pneumonitis associated with immune checkpoint inhibitor. Abstract Immune checkpoint inhibitors (ICIs) have successfully treated a number of different types of cancer, which is of great significance for cancer treatment.
Wenxian Wang   +79 more
wiley   +1 more source

Bendamustine and pneumocystis pneumonia: A systematic review

open access: yesHealth Science Reports, Volume 5, Issue 3, May 2022., 2022
Abstract Background Bendamustine, a bifunctional mechlorethamine alkylating agent, is used in the treatment of patients with hematologic malignancies. Myelosuppression and cytotoxic effect arises quite often after bendamustine treatment. To date, there have been no recommendations for routine chemoprophylaxis for Pneumocystis carinii pneumonia (PCP) in
Atousa Hakamifard   +3 more
wiley   +1 more source

Comorbidities in women living with HIV: A systematic review

open access: yesHIV Medicine, Volume 23, Issue 4, Page 331-361, April 2022., 2022
Abstract Objectives Effective antiretroviral therapy (ART) has improved the life expectancy of women living with HIV (WLWH). This population is now experiencing age‐related comorbidities. This systematic review presents the current understanding of the prevalence and impact of comorbidities in WLWH in the modern ART era. Methods MEDLINE and Embase were
Sonia Raffe   +4 more
wiley   +1 more source

Crossover between the control of fungal pathogens in medicine and the wider environment, and the threat of antifungal resistance

open access: yesPlant Pathology, Volume 71, Issue 1, Page 131-149, January 2022., 2022
The origin and emergence of resistance to antifungal compounds are evaluated and potential “hot spots” identified for major life‐theatening fungal human pathogens in medical and environmental settings. Abstract Fungal propagules existing in the natural environment can easily be transmitted to the human body, mostly by inhalation of contaminated air or ...
Ulrich Gisi
wiley   +1 more source

Functional characterization of the Pneumocystis jirovecii potential drug targets dhfs and abz2 involved in folate biosynthesis. [PDF]

open access: yes, 2015
Pneumocystis species are fungal parasites colonizing mammal lungs with strict host specificity. Pneumocystis jirovecii is the human-specific species and can turn into an opportunistic pathogen causing severe pneumonia in immunocompromised individuals ...
Cissé, O.H.   +4 more
core   +1 more source

Unusual Radiographic Presentation of Pneumocystis Pneumonia in a Patient with AIDS. [PDF]

open access: yes, 2017
Pneumocystis jirovecii pneumonia (PCP) typically presents as an interstitial and alveolar process with ground glass opacities on chest computed tomography (CT).
Block, Brian L   +6 more
core   +3 more sources

Scaling-up co-trimoxazole prophylaxis in HIV-exposed and HIV-infected children in high HIV-prevalence countries. [PDF]

open access: yes, 2007
Co-trimoxazole (trimethoprim-sulfamethoxazole) is a widely available antibiotic that substantially reduces HIV-related morbidity and mortality in both adults and children.
Abdel-Haq   +33 more
core   +2 more sources

Comment on “Pneumocystis jirovecii Pneumonia in a HIV‐Infected Patient with a CD4 Count Greater Than 400 Cells/μL and Atovaquone Prophylaxis”

open access: yes, 2023
Case Reports in Infectious Diseases, Volume 2023, Issue 1, 2023.
Gilles Nevez   +3 more
wiley   +1 more source

Comparative genomics suggests that the human pathogenic fungus Pneumocystis jirovecii acquired obligate biotrophy through gene loss. [PDF]

open access: yes, 2014
Pneumocystis jirovecii is a fungal parasite that colonizes specifically humans and turns into an opportunistic pathogen in immunodeficient individuals. The fungus is able to reproduce extracellularly in host lungs without eliciting massive cellular death.
Cissé, O.H., Hauser, P.M., Pagni, M.
core   +1 more source

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