Results 11 to 20 of about 3,561 (170)
Co‐trimoxazole prophylaxis for children who are HIV‐exposed and uninfected: a systematic review
Abstract Introduction Co‐trimoxazole prophylaxis is recommended for children born to women with HIV to protect those who acquire HIV from opportunistic infections, severe bacterial infections and malaria. With scale‐up of maternal antiretroviral therapy, most children remain HIV‐exposed uninfected (HEU) and the benefits of universal co‐trimoxazole are ...
Catherine J. Wedderburn +6 more
wiley +1 more source
Chinese expert consensus on the multidisciplinary management of pneumonitis associated with immune checkpoint inhibitor. Abstract Immune checkpoint inhibitors (ICIs) have successfully treated a number of different types of cancer, which is of great significance for cancer treatment.
Wenxian Wang +79 more
wiley +1 more source
Bendamustine and pneumocystis pneumonia: A systematic review
Abstract Background Bendamustine, a bifunctional mechlorethamine alkylating agent, is used in the treatment of patients with hematologic malignancies. Myelosuppression and cytotoxic effect arises quite often after bendamustine treatment. To date, there have been no recommendations for routine chemoprophylaxis for Pneumocystis carinii pneumonia (PCP) in
Atousa Hakamifard +3 more
wiley +1 more source
Comorbidities in women living with HIV: A systematic review
Abstract Objectives Effective antiretroviral therapy (ART) has improved the life expectancy of women living with HIV (WLWH). This population is now experiencing age‐related comorbidities. This systematic review presents the current understanding of the prevalence and impact of comorbidities in WLWH in the modern ART era. Methods MEDLINE and Embase were
Sonia Raffe +4 more
wiley +1 more source
The origin and emergence of resistance to antifungal compounds are evaluated and potential “hot spots” identified for major life‐theatening fungal human pathogens in medical and environmental settings. Abstract Fungal propagules existing in the natural environment can easily be transmitted to the human body, mostly by inhalation of contaminated air or ...
Ulrich Gisi
wiley +1 more source
Functional characterization of the Pneumocystis jirovecii potential drug targets dhfs and abz2 involved in folate biosynthesis. [PDF]
Pneumocystis species are fungal parasites colonizing mammal lungs with strict host specificity. Pneumocystis jirovecii is the human-specific species and can turn into an opportunistic pathogen causing severe pneumonia in immunocompromised individuals ...
Cissé, O.H. +4 more
core +1 more source
Unusual Radiographic Presentation of Pneumocystis Pneumonia in a Patient with AIDS. [PDF]
Pneumocystis jirovecii pneumonia (PCP) typically presents as an interstitial and alveolar process with ground glass opacities on chest computed tomography (CT).
Block, Brian L +6 more
core +3 more sources
Scaling-up co-trimoxazole prophylaxis in HIV-exposed and HIV-infected children in high HIV-prevalence countries. [PDF]
Co-trimoxazole (trimethoprim-sulfamethoxazole) is a widely available antibiotic that substantially reduces HIV-related morbidity and mortality in both adults and children.
Abdel-Haq +33 more
core +2 more sources
Case Reports in Infectious Diseases, Volume 2023, Issue 1, 2023.
Gilles Nevez +3 more
wiley +1 more source
Comparative genomics suggests that the human pathogenic fungus Pneumocystis jirovecii acquired obligate biotrophy through gene loss. [PDF]
Pneumocystis jirovecii is a fungal parasite that colonizes specifically humans and turns into an opportunistic pathogen in immunodeficient individuals. The fungus is able to reproduce extracellularly in host lungs without eliciting massive cellular death.
Cissé, O.H., Hauser, P.M., Pagni, M.
core +1 more source

