Results 41 to 50 of about 2,422 (163)

Epidemiology of Pneumocystis jirovecii Pneumonia and (Non-)use of Prophylaxis

Frontiers in Cellular and Infection Microbiology, 2020
Objectives:Pneumocystis jirovecii pneumonia (PCP) is an AIDS-defining illness. In patients with HIV, the benefit of PCP prophylaxis is well-defined when the CD4 T-cell count decreases below 200 cells/μL.
Albert Dunbar, Alexander Schauwvlieghe, Alexander Schauwvlieghe, Alexander Schauwvlieghe, Sheruna Algoe, Jaap J. van Hellemond, Marijke Reynders, Stefaan Vandecasteele, Jerina Boelens, Pieter Depuydt, Bart Rijnders   +10 more
doaj   +1 more source

Establishment and Preliminary Application of a Multiplex TaqMan Real-Time Fluorescence Quantitative PCR Assay for the Detection of Pneumocystis Species

Microorganisms
Pneumocystis is an opportunistic fungal pathogen that causes severe Pneumocystis pneumonia (PCP) in immunocompromised individuals and laboratory animals. Three host-specific species—Pneumocystis murina (P. murina), Pneumocystis carinii (P.
Qiuyang Sun, Yuanzhi Xie, Yufang Feng, Qiang Gao, Rui Fu, Jin Xing   +5 more
doaj   +1 more source

Safety of sulfamethoxazole–trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta‐analysis with active comparator disproportionality analysis

British Journal of Clinical Pharmacology, Volume 91, Issue 6, Page 1632-1648, June 2025.
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Rebecca Preyra, Lujain Ez Eddin, Fatemeh Ahmadi, Atefeh Jafari, Flory T. Muanda   +4 more
wiley   +1 more source

Abstract Book for the 27th Congress of the European Hematology Association

, 2022
HemaSphere, Volume 6, Issue S3, Page 1-4130, June 2022.
wiley   +1 more source

Laboratory-based surveillance of Pneumocystis jirovecii pneumonia in South Africa, 2006–2010i

Southern African Journal of Infectious Diseases, 2016
Background: We aimed to establish the characteristics of patients with confirmed Pneumocystis jirovecii pneumonia recruited by passive, sentinel laboratory-based surveillance.
Desiree du Plessis, Bhavani Poonsamy, Veerle Msimang, Leigh Davidsson, Cheryl Cohen, Nelesh Govender, Halima Dawood, Alan Karstaedt, John Frean   +8 more
doaj   +1 more source

Pneumocystis jirovecii pneumonia–Immune reconstitution inflammatory syndrome: A review of published cases

HIV Medicine, Volume 26, Issue 6, Page 839-848, June 2025.
Abstract Background Immune reconstitution inflammatory syndrome (IRIS) can occur in patients with HIV after commencing antiretroviral therapy. Tuberculosis–IRIS is the most common, and Pneumocystis jirovecii pneumonia (PJP)–IRIS accounts for only 2.7%–4% of IRIS cases.
Natasha Marcella Vaselli, Kris Salaveria, James Winearls, Katherine Garnham   +3 more
wiley   +1 more source

Diagnosis of Granulomatosis With Polyangiitis in a 39‐Year‐Old Woman With a Recent History of Traveling to Malaria‐Endemic Region: A Case Report

Clinical Case Reports, Volume 13, Issue 3, March 2025.
ABSTRACT Granulomatosis with Polyangiitis (GPA) is a rare vasculitis that can complicate the diagnostic process, especially in patients with complex medical histories. This case report details a 39‐year‐old woman with situs inversus totalis, Kartagener syndrome, and hypothyroidism, who presented to the emergency department with intermittent petechiae ...
Hanie Forouzandeh, Ahmadreza Rajabi, Abbas Ali Torfeh Esfahani, Farzin Khorvash, Mansoor Karimifar   +4 more
wiley   +1 more source

Strongyloidosis Hyperinfection Syndrome in an HIV‐Infected Patient: A Rare Manifestation of Immune Reconstitution Inflammatory Syndrome

Case Reports in Infectious Diseases, Volume 2018, Issue 1, 2018., 2018
Parasitic infections such as Strongyloides stercoralis and HIV have been reported to coexist, particularly in resource‐limited settings such as India. In an immunocompromised host, S. stercoralis can progress to strongyloidiasis hyperinfection syndrome (SHS). However, SHS is not common in patients with advanced HIV disease.
Kartik Natrajan, Mahenderkumar Medisetty, Raviraj Gawali, Ajit Tambolkar, Divya Patel, Vinay Thorat, Nachiket Dubale, Vrushali Khirid, Chinmay Saraf, Ameet Dravid, Larry M. Bush   +10 more
wiley   +1 more source

Mechanisms of Surface Antigenic Variation in the Human Pathogenic Fungus Pneumocystis jirovecii

mBio, 2017
Microbial pathogens commonly escape the human immune system by varying surface proteins. We investigated the mechanisms used for that purpose by Pneumocystis jirovecii.
Emanuel Schmid-Siegert, Sophie Richard, Amanda Luraschi, Konrad Mühlethaler, Marco Pagni, Philippe M. Hauser   +5 more
doaj   +1 more source

A Case of Trimethoprim‐Sulfamethoxazole Associated Aseptic Meningitis

Clinical Case Reports, Volume 13, Issue 2, February 2025.
ABSTRACT Most cases of aseptic meningitis, or nonsuppurative meningitis, are caused by viruses or systemic diseases. Nonetheless, drug‐induced aseptic meningitis should be considered in the differential diagnosis, particularly with the recent use of antibiotics and nonsteroidal anti‐inflammatory drugs.
Malik W. Z. Khan, Abdul Moeez, Sameen Farooq, Adam Saeed, Salma Qudrat, Farishta Ali, Faheemullah Khan   +6 more
wiley   +1 more source