Results 41 to 50 of about 3,571 (170)

Safety of sulfamethoxazole–trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta‐analysis with active comparator disproportionality analysis

British Journal of Clinical Pharmacology, Volume 91, Issue 6, Page 1632-1648, June 2025.
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Rebecca Preyra, Lujain Ez Eddin, Fatemeh Ahmadi, Atefeh Jafari, Flory T. Muanda   +4 more
wiley   +1 more source

Abstract Book for the 27th Congress of the European Hematology Association

, 2022
HemaSphere, Volume 6, Issue S3, Page 1-4130, June 2022.
wiley   +1 more source

P neumocystis jirovecii pneumonia is rare in renal transplant recipients receiving only one month of prophylaxis [PDF]

, 2011
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/89470/1/tid692 ...
Arend, Batiuk, Calderón, Clark, de Boer, EBPG Expert Group on Renal Transplantation, Fishman, Fox, Gianella, Gordon, Hibberd, Kotton, Martin, Neff, Oz, Peleg, Ponce, Rabodonirina, Radisic, Schmoldt, Sollinger, Yazaki   +21 more
core   +1 more source

Pneumocystis jirovecii pneumonia–Immune reconstitution inflammatory syndrome: A review of published cases

HIV Medicine, Volume 26, Issue 6, Page 839-848, June 2025.
Abstract Background Immune reconstitution inflammatory syndrome (IRIS) can occur in patients with HIV after commencing antiretroviral therapy. Tuberculosis–IRIS is the most common, and Pneumocystis jirovecii pneumonia (PJP)–IRIS accounts for only 2.7%–4% of IRIS cases.
Natasha Marcella Vaselli, Kris Salaveria, James Winearls, Katherine Garnham   +3 more
wiley   +1 more source

Diagnosis of Granulomatosis With Polyangiitis in a 39‐Year‐Old Woman With a Recent History of Traveling to Malaria‐Endemic Region: A Case Report

Clinical Case Reports, Volume 13, Issue 3, March 2025.
ABSTRACT Granulomatosis with Polyangiitis (GPA) is a rare vasculitis that can complicate the diagnostic process, especially in patients with complex medical histories. This case report details a 39‐year‐old woman with situs inversus totalis, Kartagener syndrome, and hypothyroidism, who presented to the emergency department with intermittent petechiae ...
Hanie Forouzandeh, Ahmadreza Rajabi, Abbas Ali Torfeh Esfahani, Farzin Khorvash, Mansoor Karimifar   +4 more
wiley   +1 more source

Strongyloidosis Hyperinfection Syndrome in an HIV‐Infected Patient: A Rare Manifestation of Immune Reconstitution Inflammatory Syndrome

Case Reports in Infectious Diseases, Volume 2018, Issue 1, 2018., 2018
Parasitic infections such as Strongyloides stercoralis and HIV have been reported to coexist, particularly in resource‐limited settings such as India. In an immunocompromised host, S. stercoralis can progress to strongyloidiasis hyperinfection syndrome (SHS). However, SHS is not common in patients with advanced HIV disease.
Kartik Natrajan, Mahenderkumar Medisetty, Raviraj Gawali, Ajit Tambolkar, Divya Patel, Vinay Thorat, Nachiket Dubale, Vrushali Khirid, Chinmay Saraf, Ameet Dravid, Larry M. Bush   +10 more
wiley   +1 more source

A Case of Trimethoprim‐Sulfamethoxazole Associated Aseptic Meningitis

Clinical Case Reports, Volume 13, Issue 2, February 2025.
ABSTRACT Most cases of aseptic meningitis, or nonsuppurative meningitis, are caused by viruses or systemic diseases. Nonetheless, drug‐induced aseptic meningitis should be considered in the differential diagnosis, particularly with the recent use of antibiotics and nonsteroidal anti‐inflammatory drugs.
Malik W. Z. Khan, Abdul Moeez, Sameen Farooq, Adam Saeed, Salma Qudrat, Farishta Ali, Faheemullah Khan   +6 more
wiley   +1 more source

Plasma IL‐6/IL‐10 Ratio and IL‐8, LDH, and HBDH Level Predict the Severity and the Risk of Death in AIDS Patients with Pneumocystis Pneumonia

Journal of Immunology Research, Volume 2016, Issue 1, 2016., 2016
Objective. To identify blood biomarkers to predict severity and mortality in AIDS PCP patients. Methods. Biomarkers including clinical parameters and plasma inflammatory cytokines were assessed in 32 HIV‐infected patients with Pneumocystis pneumonia (PCP) at time of admission.
Jia Sun, Junwei Su, Yirui Xie, Michael T. Yin, Ying Huang, Lijun Xu, Qihui Zhou, Biao Zhu, Paola Nistico   +8 more
wiley   +1 more source

Prognostic factors for severe Pneumocystis jiroveci pneumonia of non-HIV patients in intensive care unit: a bicentric retrospective study [PDF]

, 2016
PJP diagnosis by methenamine and PCR in participating centers.
Bin Du, Chun-Yao Wang, Jin-Min Peng, Li Weng, Li-Qin Feng, Lie Chen, Qing-Yuan Zhan, Wei Jiang, Xiao-Yun Hu, Xu Huang   +9 more
core   +2 more sources

Identification of Orthosteric and Allosteric Pharmacological Chaperones for Mucopolysaccharidosis Type IIIB

ChemBioChem, Volume 25, Issue 15, August 1, 2024.
We modeled substrate interactions in NAGLU′s active site and predicted allosteric sites. Virtual screening against a human‐tested molecule database identified potential pharmacological chaperones (PCs). In vitro evaluations confirmed their binding to NAGLU and ability to restore enzymatic activity in MPS IIIB fibroblasts with mutant enzymes.
Juan Camilo Losada, Heidy Triana, Egdda Vanegas, Angela Caro, Alexander Rodríguez‐López, Angela Johana Espejo‐Mojica, Carlos Javier Alméciga‐Diaz   +6 more
wiley   +1 more source