Results 51 to 60 of about 2,422 (163)

Plasma IL‐6/IL‐10 Ratio and IL‐8, LDH, and HBDH Level Predict the Severity and the Risk of Death in AIDS Patients with Pneumocystis Pneumonia

Journal of Immunology Research, Volume 2016, Issue 1, 2016., 2016
Objective. To identify blood biomarkers to predict severity and mortality in AIDS PCP patients. Methods. Biomarkers including clinical parameters and plasma inflammatory cytokines were assessed in 32 HIV‐infected patients with Pneumocystis pneumonia (PCP) at time of admission.
Jia Sun, Junwei Su, Yirui Xie, Michael T. Yin, Ying Huang, Lijun Xu, Qihui Zhou, Biao Zhu, Paola Nistico   +8 more
wiley   +1 more source

Identification of Orthosteric and Allosteric Pharmacological Chaperones for Mucopolysaccharidosis Type IIIB

ChemBioChem, Volume 25, Issue 15, August 1, 2024.
We modeled substrate interactions in NAGLU′s active site and predicted allosteric sites. Virtual screening against a human‐tested molecule database identified potential pharmacological chaperones (PCs). In vitro evaluations confirmed their binding to NAGLU and ability to restore enzymatic activity in MPS IIIB fibroblasts with mutant enzymes.
Juan Camilo Losada, Heidy Triana, Egdda Vanegas, Angela Caro, Alexander Rodríguez‐López, Angela Johana Espejo‐Mojica, Carlos Javier Alméciga‐Diaz   +6 more
wiley   +1 more source

Pneumocystis jirovecii pneumonija u imunokompromitiranih [PDF]

, 2018
Pneumocystis pneumonija je infekcija uzrokovana gljivom Pneumocystis jirovecii. Mjesto ulaska u čovjeka je respiratorni sustav. Pneumocystis jirovecii (ranije P. carinii) je čest uzrok pneumonije u imunokompromitiranih bolesnika, posebno u zaraženih
Devčić, Gabrijela
core  

Molecular Evidence of Interhuman Transmission of Pneumocystis Pneumonia among Renal Transplant Recipients Hospitalized with HIV-Infected Patients

Emerging Infectious Diseases, 2004
Ten Pneumocystis jirovecii pneumonia (PCP) cases were diagnosed in renal transplant recipients (RTRs) during a 3-year period. Nosocomial transmission from HIV-positive patients with PCP was suspected because the these patients shared the same hospital ...
Meja Rabodonirina, Philippe Vanhems, Sandrine Couray-Targe, René-Pierre Gillibert, Christell Ganne, Nathalie Nizard, Cyrille Colin, Jacques Fabry, Jean-Louis Touraine, Guy van Melle, Aimable Nahimana, Patrick Francioli, Philippe M. Hauser   +12 more
doaj   +1 more source

Drug‐induced pneumonitis risk in diffuse large B‐cell/follicular lymphoma patients treated with R‐CHOP‐like regimen is associated with the use of granulocyte colony‐stimulating growth factors

Cancer Medicine, Volume 13, Issue 1, January 2024.
Our findings suggest that the use of granulocyte colony‐stimulating factors increases the incidence of drug‐induced pneumonitis in patients with diffuse large cell lymphoma and follicular lymphoma receiving R‐CHOP‐type treatment. Abstract Background Rituximab‐based combinations are the standard of care in diffuse large B‐cell lymphoma (DLBCL) and ...
Elina Kaprio, Roosa Prusila, Susanna Tokola, Milla E. L. Kuusisto, Esa Jantunen, Hanne Kuitunen, Taina Turpeenniemi‐Hujanen, Outi Kuittinen   +7 more
wiley   +1 more source

Characterization of p57, a Stage-Specific Antigen of Pneumocystis murina [PDF]

, 2017
<p>Phylogenetic analysis of p57 homologs in the genome of <em>Pneumocystis jirovecii</em>, <em>Pneumocystis carinii</em> and <em>Pneumocystis murina</em></p ...
Bradshaw, Kaitlyn, Kovacs, Joseph A., Davis, Sally A., Liang, Ma, Gamez, Monica, Bishop, Lisa R., Cisse, Ousmane H., Wang, Honghui   +7 more
core   +1 more source

Pneumocystis jirovecii Pneumonia in Children [PDF]

, 2017
Pneumocystis jirovecii (previously known as Pneumocystis carinii), a yeast-like, atypical fungus, is an important human pathogen especially in the immunocompromised hosts. It primarily causes pneumonia (P.
Dhulika Dhingra, Anirban Mandal, Amitabh Singh   +2 more
core   +1 more source

Pneumocystis jirovecii pneumonia: an old disease with a new name. [PDF]

, 2006
Pneumocystis jirovecii pneumonia has historically been one of the most common opportunistic pneumonias and life-threatening infectious complications in HIV-infected patients.
Aleksonienė, Regina,, Matulionytė, Raimonda,, Ambrozaitis, Arvydas,, Paulauskienė, Rasute,   +3 more
core  

Functional characterization of the Pneumocystis jirovecii potential drug targets dhfs and abz2 involved in folate biosynthesis [PDF]

, 2015
Pneumocystis species are fungal parasites colonizing mammal lungs with strict host specificity. Pneumocystis jirovecii is the human-specific species and can turn into an opportunistic pathogen causing severe pneumonia in immunocompromised individuals ...
Hauser, P.M., Pagni, M., Cissé, O H, Monod, M., Luraschi, A, Luraschi, A., Pagni, M, Monod, M, Hauser, P M, Cissé, O.H.   +9 more
core   +1 more source

FungalRV: adhesin prediction and immunoinformatics portal for human fungal pathogens

BMC Genomics, 2011
Background The availability of sequence data of human pathogenic fungi generates opportunities to develop Bioinformatics tools and resources for vaccine development towards benefitting at-risk patients.
Ramachandran Srinivasan, Raghunandanan Muthukurussi, Ansari Faraz, Chaudhuri Rupanjali   +3 more
doaj   +1 more source