Emerging Infectious Diseases, 2004 Ten Pneumocystis jirovecii pneumonia (PCP) cases were diagnosed in renal transplant recipients (RTRs) during a 3-year period. Nosocomial transmission from HIV-positive patients with PCP was suspected because the these patients shared the same hospital ...
Meja Rabodonirina +12 more
doaj +1 more source
Interhuman Transmission as a Potential Key Parameter for Geographical Variation in the Prevalence of Pneumocystis jirovecii Dihydropteroate Synthase Mutations [PDF]
, 2017 Background. Pneumocystis jirovecii dihydropteroate synthase (DHPS) mutations are associated with failure of prophylaxis with sulfa drugs. This retrospective study sought to better understand the geographical variation in the prevalence of these mutations.
Bille, Jacques +6 more
core
Identification and Functional Ascertainment of the Pneumocystis jirovecii Potential Drug Targets Gsc1 and Kre6 Involved in Glucan Synthesis. [PDF]
, 2017 The most efficient drug against the human pathogenic fungus Pneumocystis jirovecii is cotrimoxazole targeting the folate biosynthesis. However, resistance toward it is emerging and adverse effects occur in some patients.
Cissé, O.H. +3 more
core +1 more source
Interactions between HIV infection and chronic obstructive pulmonary disease: Clinical and epidemiological aspects [PDF]
, 2011 Introduction An association between HIV infection and chronic obstructive pulmonary disease (COPD) has been observed in several studies. Objective and methods we conducted a review of the literature linking HIV infection to COPD, focusing on clinical and
Christine Raynaud +2 more
core +2 more sources
Cancer Medicine, Volume 13, Issue 1, January 2024.Our findings suggest that the use of granulocyte colony‐stimulating factors increases the incidence of drug‐induced pneumonitis in patients with diffuse large cell lymphoma and follicular lymphoma receiving R‐CHOP‐type treatment. Abstract Background Rituximab‐based combinations are the standard of care in diffuse large B‐cell lymphoma (DLBCL) and ...
Elina Kaprio +7 more
wiley +1 more source
Consensus definitions of 14 severe acute toxic effects for childhood lymphoblastic leukaemia treatment: a Delphi consensus [PDF]
, 2016 Although there are high survival rates for children with acute lymphoblastic leukaemia, their outcome is often counterbalanced by the burden of toxic effects.
Attarbaschi, Andishe +20 more
core +2 more sources
FungalRV: adhesin prediction and immunoinformatics portal for human fungal pathogens
BMC Genomics, 2011 Background The availability of sequence data of human pathogenic fungi generates opportunities to develop Bioinformatics tools and resources for vaccine development towards benefitting at-risk patients.
Ramachandran Srinivasan +3 more
doaj +1 more source
Detection of Pneumocystis jirovecii by Two Staining Methods and Two Quantitative PCR Assays [PDF]
, 2018 : Background: : Pneumocystis jirovecii is an opportunistic pathogen that causes pneumonia, particularly in immunodeficient hosts. Materials and Methods: : We retrospectively compared the results obtained by two staining methods (toluidine blue and ...
Graf, J.-D +4 more
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Anti-Pneumocystis carinii and antiplasmodial activities of primaquine-derived imidazolidin-4-ones [PDF]
, 2008 A series of primaquine-derived imidazolidin-4-ones were screened for their in vitro activity against Pneumocystis carinii and Plasmodium falciparum W2 strain. Most compounds were active against P.
Jiri Gut +7 more
core +1 more source
Community-Acquired Pneumonia in Sub-Saharan Africa [PDF]
, 2016 Community-acquired pneumonia (CAP) in sub-Saharan Africa is a common cause of adult hospitalization and is associated with significant mortality. Human immunodeficiency virus (HIV) prevalence in the region leads to differences in CAP epidemiology ...
Aston, R J, Rylance, Jamie
core +3 more sources