Results 51 to 60 of about 49,384 (274)
CD4+ T-cell independent secondary immune responses to Pneumocystis pneumonia
Pneumocystis pneumonia is a major cause of morbidity and mortality among immunocompromised patients, especially in the context of HIV/AIDS. In the murine model of Pneumocystis pneumonia, CD4+ T-cells are required for clearance of a primary infection of ...
Nicholas M de la Rua+4 more
doaj +1 more source
In liver transplant recipients with coexistent inflammatory bowel disease, incidence of infectious events observed between those exposed to ‘gut‐specific’ and ‘systemic’ biologics were similar. Biologic choice should not be influenced by concerns regarding their co‐prescription with transplant immunosuppression.
Simone Chin+8 more
wiley +1 more source
Not COVID-19, Don’t Overlook Pneumocystis in Patients on Gefitinib!
An 82-year-old woman treated for advanced lung cancer with gefitinb was admitted to the emergency unit complaining of dyspnea. Chest computed tomography found abnormalities classified as possible diffuse COVID-19 pneumonia.
Jérémy Barben+4 more
doaj +1 more source
The overall survival of patients receiving an allogeneic haematopoietic stem cell transplant (HSCT) for GATA2 deficiency was significantly better if they were transplanted recently, with a bone marrow or cord blood graft and if the transplant was performed before the onset of excess blast. Excess blast before HSCT was the only factor associated with an
Flore Sicre de Fontbrune+20 more
wiley +1 more source
Integrating tuberculosis and HIV services in low- and middle-income countries: a systematic review.
OBJECTIVES: Given the imperative to scale up integrated tuberculosis (TB) and HIV services in settings where both are of major public health importance, we aimed to synthesise knowledge concerning implementation of TB/HIV service integration.
Atun+36 more
core +1 more source
Pneumocystis jirovecii pneumonia is a very uncommon complication in lung cancer patients. We report the case of a 59-year-old, Stage IIIB non-small cell lung cancer (epidermoid) patient who was receiving concurrent chemotherapy scheme (cisplatin ...
Kevin Doello+3 more
doaj +1 more source
CD4+ tissue‐resident memory T cells and their role in immunity
In this article, we review and discuss the role of CD4+ tissue‐resident memory T (TRM) cells and their role in immune protection in tissues, such as the lungs, by facilitating pathogen clearance through cytokine production and local immune interactions.
Margarida Kirkby, Marc Veldhoen
wiley +1 more source
AIDS-defining illnesses at initial diagnosis of HIV in a large Guatemalan cohort [PDF]
BackgroundAnecdotal evidence suggests that a high proportion of patients diagnosed with HIV in Guatemala present with AIDS. There remain limited data on the epidemiology of AIDS-defining illnesses (ADIs) in Central America.MethodsWe conducted a ...
Cordon, Andrea Alonzo+6 more
core +2 more sources
Out of 274 lung transplant (LTx) patients, 89 (32%) developed invasive aspergillosis IA. Factors associated with IA were mycophenolate mofetil use, airway stenosis, Aspergillus cultured pre‐LTx, chronic lung allograft dysfunction (CLAD), and acute rejection. The role of nebulized amphotericin B and statins for prevention of IA remains unclear. ABSTRACT
Johanna P. van Gemert+7 more
wiley +1 more source
Bacteremia in Pediatric Solid Organ Transplant Recipients within 1 Year of Transplant
We retrospectively reviewed bloodstream infections (BSI) in pediatric recipients of solid organ transplants over a 14‐year period. Overall BSI rates were significant but decreased over time. Risk factors for BSI were identified which may help identify interventions which further decrease rates.
Mario M. Landa+8 more
wiley +1 more source