Results 41 to 50 of about 24,868 (172)

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

Pediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia, Jie Zheng, Meng Yuan, Hongbo He, Yibo Fan, Bin Wang, Guanghua Zhu, Jun Yang, Yanhui Luo, Lixiao Cai, Pan Zhang, Yanlong Duan, Maoquan Qin   +12 more
wiley   +1 more source

A New Name for Pneumocystis from Humans and New Perspectives on the Host-Pathogen Relationship

Emerging Infectious Diseases, 2002
The disease known as Pneumocystis carinii pneumonia (PCP) is a major cause of illness and death in persons with impaired immune systems. While the genus Pneumocystis has been known to science for nearly a century, understanding of its members remained ...
James R. Stringer, Charles B. Beard, Robert F. Miller, Ann E. Wakefield   +3 more
doaj   +1 more source

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija, Fiona Kerr, Hazel Gough, Johnathan Soggee, Laurence C. Cheung, Rishi S. Kotecha, Shanti Ramachandran   +6 more
wiley   +1 more source

UK Infected Blood Inquiry–An Historical Appraisal

Haemophilia, EarlyView.
ABSTRACT Introduction This appraisal considers the 2018 UK Infected Blood Inquiry and its Report (2024) in the context of the history of haemophilia treatment developments over the past fifty‐five years, and the tragic impacts of the AIDS pandemic. Aim The paper appraises the conduct and findings of the IBI and its Report in relation to HIV and AIDS ...
Christopher A. Ludlam
wiley   +1 more source

Risk of urinary tract infection with SGLT2 inhibitor initiation in patients with immune‐mediated inflammatory diseases and type 2 diabetes: A target trial emulation using a Japanese hospital‐based claims database

Journal of Diabetes Investigation, EarlyView.
In this target trial emulation of patients with immune‐mediated inflammatory diseases and type 2 diabetes, SGLT2 inhibitor initiation was not associated with a clear increase in UTI risk versus metformin, including across immunosuppressive therapy strata.
Hiroshi Tsushima, Nobuyuki Yajima, Takashi Nomiyama, Ryoko Sakai, Hisashi Noma, Akira Katagiri, Naoto Tamura   +6 more
wiley   +1 more source

Outcomes of a Routine Screening Protocol to Prevent Metamycoplasma and Ureaplasma Infection in Lung Transplant Recipients

Transplant Infectious Disease, EarlyView.
This study analyzed outcomes of an early Mollicute (Mycoplasma hominis and Ureaplasma spp.) screening protocol using BAL PCR with preemptive treatment and ammonia monitoring in lung transplant recipients. This appears to be a practical and reasonably effective approach for preventing early Mollicute infection and hyperammonemia syndrome.
Lalithaa Thirunavukarasu Murugan, Anika Sasidharan Nair, Marie M. Budev, Maureen Converse, Nabin K. Shrestha, Christine E. Koval   +5 more
wiley   +1 more source

An Update on Invasive Fungal Infections in Solid Organ Transplant Recipients

Transplant Infectious Disease, EarlyView.
ABSTRACT Invasive fungal infections (IFI) remain a significant infection‐related complication in solid organ transplant recipients (SOTRs), the incidence of which has not changed overtime. With a focus on studies and data published after 2019, this narrative review provides an update on the epidemiology and prevention of IFIs in SOTRs and highlights ...
Tina Marinelli, Shahid Husain
wiley   +1 more source

Diagnostic Performance of Bronchoalveolar Lavage (1,3)-β-d-Glucan Assay for Pneumocystis jirovecii Pneumonia

Journal of Fungi, 2020
We evaluated the performance of the (1,3)-β-d-glucan (BDG) assay on bronchoalveolar lavage fluid (BALF) as a possible aid to the diagnosis of Pneumocystis jirovecii pneumonia.
Shiwei Zhou, Kathleen A. Linder, Carol A. Kauffman, Blair J. Richards, Steve Kleiboeker, Marisa H. Miceli   +5 more
doaj   +1 more source

Bridging the Gap Between General and Transplant Infectious Disease Practice

Transplant Infectious Disease, EarlyView.
ABSTRACT The population of iatrogenic immunocompromised individuals is steadily rising as we continue to improve in our ability to manage diseases, including cancer, autoimmune disease, and end‐organ dysfunction, with increasing access to novel agents and transplantation.
Jeremey Walker, Emily Eichenberger, Steven Pergam, Maricar Malinis, Andrea J. Zimmer   +4 more
wiley   +1 more source

Optimizing Pneumocystis jirovecii Prophylaxis in Immunocompromised Patients: Defining the Clinical Role of Atovaquone

Transplant Infectious Disease, EarlyView.
In a retrospective cohort study of 149 patients receiving atovaquone for PJP prophylaxis, increased usage was related to broader indications, uptake in new patient groups, difficulty tolerating or accessing alternatives, and longer durations used per patient.
To N. Pham, Kelly A. Cairns, Adithi Ramachandra, Susan G. Poole, Carmela E. Corallo, Bradley J. Gardiner   +5 more
wiley   +1 more source