Results 51 to 60 of about 191,871 (207)

Clinical Significance of Organ Preservation Fluid Cultures in Pediatric Abdominal Solid Organ Transplantation

Transplant Infectious Disease, EarlyView.
In this pediatric abdominal solid organ transplant cohort, preservation fluid‐related infections were rare but occurred in infant liver transplant recipients whose preservation fluid cultures grew pathogenic organisms. These findings suggest that routine bacterial preservation fluid cultures may be most useful for identifying clinically significant ...
Hassan A. Jamal, Yong K. Kwon, Pamela L. Valentino, Jodi M. Smith, Patrick J. Healey, Zheyi Teoh   +5 more
wiley   +1 more source

Pneumocystis pneumonia mimicking COVID-19 [PDF]

, 2020
Background. The new coronavirus infection COVID-19 caused by a SARS-CoV-2 zoonotic beta-coronavirus has radically transformed the conventional concept of the immune systems participation in an infectious process.
Alexander V. Averyanov, Viktor N. Lesnyak, Anna G. Sotnikova   +2 more
core   +1 more source

Invasive Fungal Infections in Heart Transplants: A 10‐Year, Single Centre Retrospective Cohort Study From Subtropical Australia

Transplant Infectious Disease, EarlyView.
In this 10‐year retrospective cohort study of heart transplant recipients in subtropical Australia, we characterize the incidence and microbiological profile of invasive fungal infections, highlighting the underappreciated burden of late‐onset and non‐Aspergillus mold infections and the potential underdiagnosis of polymicrobial disease.
Angus Lane, Karen Hay, John McNamara, Alex Chaudhuri, Andrew Burke, Robert Horvath, Maryam Khorramshahi Bayat, Kanthi Vemuri   +7 more
wiley   +1 more source

Diagnostic Performance of Bronchoalveolar Lavage (1,3)-β-d-Glucan Assay for Pneumocystis jirovecii Pneumonia

Journal of Fungi, 2020
We evaluated the performance of the (1,3)-β-d-glucan (BDG) assay on bronchoalveolar lavage fluid (BALF) as a possible aid to the diagnosis of Pneumocystis jirovecii pneumonia.
Shiwei Zhou, Kathleen A. Linder, Carol A. Kauffman, Blair J. Richards, Steve Kleiboeker, Marisa H. Miceli   +5 more
doaj   +1 more source

Feasibility and Safety of Venetoclax for Cytoreduction During Induction Therapy in Newly Diagnosed Acute Promyelocytic Leukemia

European Journal of Haematology, Volume 117, Issue 5, Page 1258-1264, November 2026.
ABSTRACT Objective This study aimed to evaluate the feasibility and safety of venetoclax as a cytoreductive strategy during induction therapy in newly diagnosed acute promyelocytic leukemia (APL), and to provide an exploratory description of its early efficacy.
Yu Wang, Rong Xiao, Xiaobing Huang, Yi Xiao   +3 more
wiley   +1 more source

A case of spontaneous pneumothorax, pneumomediastinum & subcutaneous emphysema in Pneumocystis jirovecii pneumonia complicating HIV

Sri Lankan Journal of Infectious Diseases, 2015
Spontaneous pneumothorax and subcutaneous emphysema are well-known but less common complications of pneumocystis pneumonia, whereas pnuemomediastinum is rare.
S Chatterji, D Pal, MK Ghosh, A Naskar, S Pal, S Mullick, I Bhattacharya   +6 more
doaj   +1 more source

Virtual Screening of Phytochemicals to Novel Target (HAT) Rtt109 in Pneumocystis Jirovecii using Bioinformatics Tools [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Pneumocystis jirovecii is a fungus that causes Pneumocystis pneumonia in HIV and other immunosuppressed patients. Treatment of Pneumocystis pneumonia with the currently available antifungals is challenging and associated with ...
Ramya Sugumar, Abhinand Ponneri Adithavarman, Anusha Dakshinamoorthi, Darling Chellathai David, Padmavathi Kannan Ragunath   +4 more
doaj   +1 more source

Adverse Reactions Identified after Approval of Novel Medicines: Analysis of 339 New Molecular Entities and Therapeutic Biologics

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1120-1128, October 2026.
Postmarketing safety surveillance data identify safety issues not identified in preapproval clinical trials. We describe the frequency of new safety issues overall and by labeling section and the relationship of the most commonly added safety issues with the cumulative number of prescriptions dispensed via retail pharmacies.
Ellen Pinnow, Brendan Day, Esther H. Zhou, Corinne Woods, Nana Dwumfour, Jenni Y. Lee, Ilynn Bulatao, Sanae Cherkaoui, Manish Kalaria, Sonja Brajovic, Nabila Sadiq, Farideh Sistani, Maggie Lee, Grace Chai, Gerald Dal Pan   +14 more
wiley   +1 more source

Frequency of trichomonads as coinfecting agents in Pneumocystis pneumonia

OBJECTIVE: To investigate the incidence of the association of Trichomonas and Pneumocystis in the lung. STUDY DESIGN: Sixty-six bronchoalveolar lavage fluid (BALF) samples from immunocompromised patients with pneumocystosis were retrospectively examined ...
Durand-Joly I, Leclerc C, Capron M, Duboucher C, Viscogliosi E, Gerbod D, Pham S, Noel C, Delgado-Viscogliosi P, Dei-Cas E   +9 more
core   +5 more sources

CD4+ T-cell independent secondary immune responses to Pneumocystis pneumonia

Frontiers in Immunology, 2016
Pneumocystis pneumonia is a major cause of morbidity and mortality among immunocompromised patients, especially in the context of HIV/AIDS. In the murine model of Pneumocystis pneumonia, CD4+ T-cells are required for clearance of a primary infection of ...
Nicholas M de la Rua, Derrick Richard Samuelson, Tysheena P Charles, David Allen Welsh, Judd E. Shellito   +4 more
doaj   +1 more source