Results 91 to 100 of about 21,263 (258)

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Improving Early Identification of Microbial Etiology in Severe Pediatric Pneumonia by Using Inflammatory Profiles: A Cross-sectional Study

Güncel Pediatri
Introduction: Pediatric pneumonia can result from bacterial or viral pathogens, presenting with overlapping clinical features, which makes accurate differentiation challenging.
Quang Chi Ngo, Hung Do Tran, Nhan Thanh Thi Nguyen, My Le Hoang, Loan Kim Thi Duong   +4 more
doaj   +1 more source

Procalcitonin and C-reactive protein for invasive bacterial pneumonia diagnosis among children in Mozambique, a malaria-endemic area.

PLoS ONE, 2010
BackgroundPneumonia is the major cause of mortality and morbidity in children worldwide. Procalcitonin (PCT) and C-reactive protein (CRP) are used in developed countries to differentiate between viral and bacterial causes of pneumonia.
Núria Díez-Padrisa, Quique Bassat, Sonia Machevo, Llorenç Quintó, Luis Morais, Tacilta Nhampossa, Cristina O'Callaghan-Gordo, Antoni Torres, Pedro L Alonso, Anna Roca   +9 more
doaj   +1 more source

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc, Guillaume St‐Jean, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Pneumonija kod bolesnika sa imunskim deficitom [PDF]

Vojnosanitetski Pregled, 2002
Marinković Olivera, Aćimović Slobodan
doaj   +1 more source

Clinical characteristics and predictive models for hospitalized patients with COVID-19 combined with bacterial pneumonia.

PLoS ONE
BackgroundThis study aimed to analyze the clinical characteristics of hospitalized patients with COVID-19 combined with bacterial pneumonia and establish a predictive model to assist clinicians in the differential diagnosis and evaluation of the ...
Man Yuan, Mei Liang, Jian Xu, Da He, Yanfang Zhang, Xiaoran Li, Jinzhi He, Yang Yang, Zhiyong Zong, Junyan Qu   +9 more
doaj   +1 more source

The role of statins in prevention and treatment of community acquired pneumonia: a systematic review and meta-analysis.

, 2013
BACKGROUND: Emerging epidemiological evidence suggests that statins may reduce the risk of community-acquired pneumonia (CAP) and its complications. PURPOSE: Performed a systematic review to address the role of statins in the prevention or treatment ...
Imad M Tleyjeh, Khan Abdur Rahman, Mohamad A. Al-Tannir (104241), Imad M. Tleyjeh (104252), Tleyjeh, I. M., Patricia J Erwin, Muhammad Riaz, Abdur Rahman Khan (104234), Garbati, MA, Muhammad Riaz (104236), Bin Abdulhak, AA, Bin Abdulhak Aref A., Erwin, PJ, Baddour, LM, Riaz Muhammad, Musa A Garbati, Aref A. Bin Abdulhak (5648656), Patricia J. Erwin (104246), Abdur Rahman Khan, Al-Tannir Mohamad A., Riaz, M., Khan, AR, Al-Tannir, MA, Tleyjeh, IM, Erwin Patricia J., Larry M Baddour, Baddour Larry M., Khan, A. R., Garbati, M. A., Garbati Musa A., Al-Tannir, M. A., Larry M. Baddour (104249), Riaz, M, Aref A Bin Abdulhak, Mohamad A Al-Tannir, Bin Abdulhak, A. A., Tleyjeh Imad M., Erwin, P. J., Baddour, L. M., Musa A. Garbati (104244)   +39 more
core   +1 more source

Risk factors for chest infection in acute stroke: a prospective cohort study [PDF]

, 2007
<p><b>Background and Purpose:</b> Pneumonia is a major cause of morbidity and mortality after stroke. We aimed to determine key characteristics that would allow prediction of those patients who are at highest risk for poststroke ...
Tilston, J., Bowie, L., Hazel Miller, Sellars, C., David J. Stott, Jeremy Bagg, Peter Langhorne, Lynsey Bowie, Langhorne, P., Jennifer Tilston, Bagg, J., M. Petrina Sweeney, Stott, D.J., Cameron Sellars, Sweeney, M.P., Miller, H.   +15 more
core   +1 more source

Anti‐NMDA receptor autoimmune encephalitis associated with ovarian teratoma: A case series and literature review

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 23-30, April 2025.
Abstract Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra‐limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti‐NMDA (N‐methyl‐D‐aspartate) receptor encephalitis was first described in 2007
Pham Ba Nha, Nguyen Phuong Tu, Nguyen Viet Ha, Duong Thi Thu Hien, Nguyen Thi Thu Phuong, Nguyen Anh Son, Nguyen Tien Hoang   +6 more
wiley   +1 more source

Can clinical findings at admission allow withholding of antibiotics in patients hospitalized for community acquired pneumonia when a test for a respiratory virus is positive?

Pneumonia
Background Current guidelines recommend empiric antibiotic therapy for patients who require hospitalization for community-acquired pneumonia (CAP). We sought to determine whether clinical, imaging or laboratory features in patients hospitalized for CAP ...
Ryan Ward, Alejandro J. Gonzalez, Justin A. Kahla, Daniel M. Musher   +3 more
doaj   +1 more source