Results 71 to 80 of about 1,205,800 (294)

Vaccination for the control of childhood bacterial pneumonia - Haemophilus influenzae type b and pneumococcal vaccines

, 2013
Pneumonia in childhood is endemic in large parts of the world and in particular, in developing countries, as well as in many indigenous communities within developed nations.
Allan W Cripps, Cripps, Allan W, Otczyk, Diana C, Diana C Otczyk   +3 more
core   +1 more source

Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease. [PDF]

, 2014
BACKGROUND: Inhaled corticosteroids (ICS) are anti-inflammatory drugs that have proven benefits for people with worsening symptoms of chronic obstructive pulmonary disease (COPD) and repeated exacerbations.
Seniukovich, A, Alieksei Seniukovich, Kew, KM, Kayleigh M Kew   +3 more
core   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Rational Design of a Synthetic Galliphore for the Diagnostic Nuclear Imaging and Treatment of Bacterial Infections

Angewandte Chemie, EarlyView.
KO‐NH2 is a synthetic metallophore that preferentially binds Ga3+ over Fe3+ and is recognized by bacterial transporters. Photocrosslinking identifies CirA and Fiu as key uptake proteins in E. coli. KO‐NH2 enables targeted imaging and treatment of E. coli soft tissue infections.
Phuong Nguyen Tran, Axia Marlin, Edith K. Amason, Marie Huynh, Hannah Carlisle, Eszter Boros   +5 more
wiley   +2 more sources

Accurately Discriminating COVID-19 from Viral and Bacterial Pneumonia According to CT Images Via Deep Learning

, 2021
Computed tomography (CT) is one of the most efficient diagnostic methods for rapid diagnosis of the widespread COVID-19. However, reading CT films brings a lot of concentration and time for doctors.
Chen, Z, Li, L, Wu, J, Shen, J, Huang, Z, Zha, Y, Zheng, F, Yang, Y, Zhao, H, Zhang, X, Zhu, H, Chen, W, Lu, Y, Song, Y, Chong, Y   +14 more
core   +1 more source

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

What Does it Mean When a Child is Diagnosed with Pneumonia?

Pediatric Respirology and Critical Care Medicine, 2019
Pneumonia is a frequent diagnosis without adequate consideration of the etiology. Pneumonia implies the presence of inflammation of the lung parenchyma with consolidation. That inflammation may be from infectious or noninfectious causes.
Miles Weinberger
doaj   +1 more source

Atypical bacterial pneumonia in the HIV-infected population

, 2017
Human immunodeficiency virus (HIV)-infected individuals are more susceptible to respiratory tract infections by other infectious agents (viruses, bacteria, parasites, and fungi) as their disease progresses to acquired immunodeficiency syndrome.
Adriana Trajtman, Trajtman, Adriana, Rueda Vallejo, Zulma Vanessa, Breanne M. Head, Yoav Keynan, Vélez Giraldo, Lazaro Agustín, Lázaro Vélez, Head, Breanne, Zulma V. Rueda, Head, Breanne M, Vélez, Lázaro, Rueda, Zulma V, Keynan, Yoav   +12 more
core   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Clinical and Etiological Features of Community-acquired Pneumonia in Children in Vladivostok

Детские инфекции (Москва), 2015
A survey of 991 with community-acquired pneumonia. The disease is most proceeded in the average severity (97.2 %). In 99.4 % of cases diagnosed focal, polysegmental pneumonia in 0.6% of cases.
L. G. Erokhina, O. G. Savina, T. O. Svirinkova, M. A. Terpugova   +3 more
doaj   +1 more source