Results 31 to 40 of about 3,636 (153)
Community and Hospital-Based Laboratory Surveillance for Influenza, Respiratory Syncytial Virus, and SARS-CoV-2 During the 2023-2024 Season, Lyon, France. [PDF]
ABSTRACT Influenza, respiratory syncytial virus (RSV) and SARS‐CoV‐2 are among the main respiratory viruses circulating in the population, with a significant burden on public health. While individuals at higher risk are more likely to develop severe symptoms leading to hospitalization, viral circulation in the community remains less extensively ...
Chauvel C +18 more
europepmc +2 more sources
Prevention of severe lower respiratory tract infections in infants caused by the human respiratory syncytial virus (hRSV) remains a major public health priority. Currently, the major focus of vaccine development relies on the RSV fusion (F) protein since
Annelies Leemans +12 more
doaj +1 more source
Avian Metapneumovirus Review: A Focus on Broilers [PDF]
Avian Metapneumovirus infection first emerged in South African turkeys, followed by respiratory problems in chickens with a swollen head syndrome. The etiological agent is a Metapneumovirus in the Pneumoviridae family and the first pneumovirus identified
Amine Mernizi +6 more
doaj +1 more source
Glucocorticoid Administration Accelerates Mortality of Pneumovirus‐Infected Mice [PDF]
The use of glucocorticoids for the treatment of symptoms associated with respiratory syncytial virus (RSV) infection has been questioned. To evaluate the sequelae of glucocorticoid administration in the setting of pneumovirus infection in vivo, hydrocortisone was administered to mice infected with pneumonia virus of mice (PVM), a pneumovirus and ...
J B, Domachowske +5 more
openaire +2 more sources
The Changing Landscape of Respiratory Syncytial Virus Infections
Respiratory syncytial virus (RSV), a negative-sense, enveloped RNA virus of the family Paramyxoviridae, subfamily Pneumovirinae, and genus Pneumovirus, is the single most important respiratory pathogen affecting infants and young children [...]
Reinout A. Bem, Job B. M. van Woensel
doaj +1 more source
Human respiratory syncytial virus (hRSV) infection brings a wide spectrum of clinical outcomes, from a mild cold to severe bronchiolitis or even acute interstitial pneumonia. Among the known factors influencing this clinical diversity, genetic background
Gautier Gilliaux, Daniel Desmecht
doaj +1 more source
Host Cell Restriction Factors of Paramyxoviruses and Pneumoviruses
The paramyxo- and pneumovirus family includes a wide range of viruses that can cause respiratory and/or systemic infections in humans and animals. The significant disease burden of these viruses is further exacerbated by the limited therapeutics that are
Rubaiyea Farrukee +4 more
doaj +1 more source
Pneumovirus-Induced Lung Disease in Mice Is Independent of Neutrophil-Driven Inflammation. [PDF]
The human pneumovirus respiratory syncytial virus (RSV) is the most common pathogen causing lower respiratory tract disease in young children worldwide.
Bart Cortjens +4 more
doaj +1 more source
Interferon-Mediated Response to Human Metapneumovirus Infection
Human metapneumovirus (HMPV) is one of the leading causes of respiratory diseases in infants and children worldwide. Although this pathogen infects mainly young children, elderly and immunocompromised people can be also seriously affected. To date, there
Ifeanyi K. Uche +1 more
doaj +1 more source
Structure of the RSV Polymerase Complex Reveals a Tentacular Arrangement of the Viral Phosphoprotein
Numerous interventions are currently in the process of clinical development for respiratory syncytial virus (RSV) infection, including the use of small molecules that target viral transcription and replication.
Jason S. McLellan
doaj +1 more source

