Characterization of human metapneumoviruses isolated from patients in North America. [PDF]
Human metapneumovirus (HMPV) was recently identified in The Netherlands and was linked to acute respiratory tract illness. In this study, 11 isolates from 10 patients with respiratory disease from Quebec, Canada, were tested by a reverse-transcriptase ...
Anderson, L.J. (Larry) +7 more
core +4 more sources
Pneumovirus-Induced Lung Disease in Mice Is Independent of Neutrophil-Driven Inflammation. [PDF]
The human pneumovirus respiratory syncytial virus (RSV) is the most common pathogen causing lower respiratory tract disease in young children worldwide.
Bart Cortjens +4 more
doaj +1 more source
Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases [PDF]
Respiratory tract disease can be associated with primary or secondary bacterial infections in dogs and cats and is a common reason for use and potential misuse, improper use, and overuse of antimicrobials.
Allen +101 more
core +4 more sources
Human metapneumovirus: Mechanisms and molecular targets used by the virus to avoid the immune system [PDF]
Indexación: Scopus.This work was supported by Comisión Nacional de Investigación Científica y Tecnolígica (CONICYT) N◦21151028 and FONDECYT (N◦1070352 and N◦1170964) and the Millennium Institute on Immunology and Immunotherapy (P09/016-F).Human ...
Benavente, F.M. +8 more
core +1 more source
Molecular assays for detection of human metapneumovirus [PDF]
The recent description of the respiratory pathogen human metapneumovirus (hMPV) has highlighted a deficiency in current diagnostic techniques for viral agents associated with acute lower respiratory tract infections.
Mackay, Ian M. +8 more
core +2 more sources
Interferon-Mediated Response to Human Metapneumovirus Infection
Human metapneumovirus (HMPV) is one of the leading causes of respiratory diseases in infants and children worldwide. Although this pathogen infects mainly young children, elderly and immunocompromised people can be also seriously affected. To date, there
Ifeanyi K. Uche +1 more
doaj +1 more source
Structure of the RSV Polymerase Complex Reveals a Tentacular Arrangement of the Viral Phosphoprotein
Numerous interventions are currently in the process of clinical development for respiratory syncytial virus (RSV) infection, including the use of small molecules that target viral transcription and replication.
Jason S. McLellan
doaj +1 more source
Nasally administered Lactobacillus rhamnosus strains differentially modulate respiratory antiviral immune responses and induce protection against respiratory syncytial virus infection [PDF]
Some studies have shown that nasally administered immunobiotics had the potential to improve the outcome of influenza virus infection. However, the capacity of immunobiotics to improve protection against respiratory syncytial virus (RSV) infection was ...
Alvarez, Gladis Susana +7 more
core +2 more sources
Investigations into the utility of real-time PCR for the detection, quantitation and characterisation of clinically relevant viruses [PDF]
The use of PCR as a tool for the diagnostic virology and viral research laboratories has greatly increased in recent years, however the use of conventional PCR and amplicon detection systems can be a complex and relatively slow process that increases the
Mackay, Ian M.
core +1 more source
Critical Adverse Impact of IL-6 in Acute Pneumovirus Infection [PDF]
Abstract Severe respiratory virus infections feature robust local host responses that contribute to disease severity. Immunomodulatory strategies that limit virus-induced inflammation may be of critical importance, notably in the absence of antiviral vaccines.
Caroline M Percopo +6 more
openaire +5 more sources

