Results 91 to 100 of about 10,942 (165)

A machine learning algorithm for the detection of paroxysmal nocturnal haemoglobinuria (PNH) in UK primary care electronic health records

Orphanet Journal of Rare Diseases
Background Paroxysmal Nocturnal Haemoglobinuria (PNH) is an ultra-rare, acquired disorder that is challenging to diagnose due to varied symptoms, heterogeneous patient presentations, and lack of awareness among healthcare professionals.
Amanda Worker, Hadley Mahon, Jack Sams, Freya Boardman-Pretty, Elena Marchini, Rand Dubis, Alan Warren, Jez Stockdale, Jyothika Kumar, Elizabeth Varones, Daniel Ollerenshaw, Calum Grant, Peter Fish, Richard J. Kelly   +13 more
doaj   +1 more source

Paroxysmal nocturnal haemoglobinuria: a case presenting with isolated thrombocytopenia

Biotechnology & Biotechnological Equipment, 2016
Paroxysmal nocturnal haemoglobinuria (PNH) is a rare disease characterized by intravascular haemolysis, haemoglobinuria and thrombosis. The present study reported PNH patients presenting with isolated thrombocytopenia.
Mustafa Yilmaz, Beyhan Guvercin, Ceren Konca   +2 more
doaj   +1 more source

Real-World Prevalence and Outcomes of Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with C5 Inhibitors in the US: A Retrospective Claims Database Analysis

Journal of Health Economics and Outcomes Research
# Background Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disorder with C5 inhibitors (C5i), eculizumab and ravulizumab, being part of current treatment options.
Srinivas K Tantravahi, Dominick Latremouille-Viau, Raj Desai, Soyon Lee, Jincy Paulose, Anumaxine Geevarghese, Annie Guérin, Shravanthi Seshasayee, Mohin Chanpura, Glorian Yen   +9 more
doaj   +1 more source

Εργαστηριακά ευρήματα της παροξυντικής νυκτερινής αιμοσφαιρινουρίας (PNH)

Η Παροξυντική Νυκτερινή Αιμοσφαιρινουρία (PNH) ή Marchiafava-Micheli σύνδρομο, είναι μία σπάνια επίκτητη, κλωνική διαταραχή του αρχέγονου αιμοποιητικού κυττάρου, που χαρακτηρίζεται από την εμφάνιση αιμολυτικής αναιμίας, μυελικής ανεπάρκειας και θρόμβωσης.
Goulou Christina, Γούλου Χριστίνα   +1 more
core  

Addressing Inequality of Access to Biologics: What Is Your Role? A Patient (Advocate)’s Perspective on Biosimilars

HemaSphere, 2022
Maria M. Piggin
doaj   +1 more source

A Systemic Lupus Erythematosus Patient with Isolated Neutropenia and Diminished Expression of CD55 and CD59 Similar to Paroxysmal Nocturnal Hemoglobinuria

Turkish Journal of Hematology, 2014
Abdülkerim Yıldız, Merih Kızıl Çakar, Elif Suyanı, Gülsan Türköz Sucak   +3 more
doaj   +1 more source

A Game of Clones: The Complex Interplay of Aplastic Anaemia, Myelodysplastic Syndrome, and Paroxysmal Nocturnal Haemoglobinuria

European Medical Journal, 2018
Although idiopathic aplastic anaemia (AA), myelodysplastic syndrome (MDS), and paroxysmal nocturnal haemoglobinuria (PNH) are all associated with bone marrow failure, they have traditionally been understood as distinct diseases with sharply contrasting ...
Hayeong Rho, Richard A Wells
doaj  

PO60 | Asymptomatic PNH clone in acquired aplasia (AA)

Bleeding, Thrombosis and Vascular Biology
Background: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired clonal hematopoietic cell disease characterized by destruction of hematopoietic cells through the activation of the complement system with manifestations that can be life ...
doaj   +1 more source

FACIT-fatigue score and treatment quality assessment for paroxysmal nocturnal hemoglobinuria patients treated with Eculizumab in Türkiye. [PDF]

PLoS One
Narlı Özdemir Z, Keklik Karadağ F, Acar NG, Aydoğan M, Yavaşoğlu F, Temiz F, Güneş A, Akyol G, Erol HA, Mehtap Ö, Okan V, Kakçı M, Kendir İC, Köksal T, Iltar U, Esen R, Korkmaz G, Ayer M, Oğuz E, Salim O, Tombak A, Özet G, Sönmez M, Güler N, Yilmaz M, Özcan MA, Ünal A, Tuğlular T, Toprak SK, Güvenç B, Yenerel MN, İlhan O, Saydam G, Şahin F.   +33 more
europepmc   +1 more source

A highly selective pyrazole-hydrazide-based colorimetric and "turn on" fluorometric sensor for fluoride with portable device applications. [PDF]

RSC Adv
Nesaragi AR, Alsaad AMS, Iqbal M, Nagalik J, Benni S, T M S, Bansal N, Gurjeet Singh T, Verma A, Majumder P, Inamdar SR, Imam F.   +11 more
europepmc   +1 more source