Results 81 to 90 of about 10,942 (165)

Cost-Utility Analysis Comparing Pegcetacoplan to Anti-C5 Monoclonal Antibodies in the Treatment of Paroxysmal Nocturnal Hemoglobinuria

ClinicoEconomics and Outcomes Research
Sergio Di Matteo,1 Roberto Freilone,2 Giacomo Matteo Bruno,1,3 Rosario Notaro,4 Sabrin Moumene,1 Nicoletta Martone,5 Cristina Teruzzi,5 Antonio Ciccarone,1 Giorgio Lorenzo Colombo1,3 1Center of Research, SAVE Studi - Health Economics and Outcomes ...
Di Matteo S, Freilone R, Bruno GM, Notaro R, Moumene S, Martone N, Teruzzi C, Ciccarone A, Colombo GL   +8 more
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Factor V Leiden mutation investigated by amplification created restriction enzyme site (ACRES) in PNH patients with and without thrombosis

Haematologica, 1996
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired chronic hemolytic anemia characterized by intravascular hemolysis, often associated with neutropenia and thrombocytopenia. Venous thrombosis, including the Budd-Chiari syndrome, is one of the major
K Nafa, M Bessler, P Mason, T Vulliamy, P Hillmen, H Castro-Malaspina, L Luzzatto   +6 more
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A PNH - ênfase na transversalidade

, 2012
Data: 30/08/2012 Palestrante: Patricia de Souza Campos da Silva Resumo: A PNH - ênfase na ...
Telessaúde SC
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Thrombosis in Paroxysmal Nocturnal Hemoglobinuria (PNH): From Pathogenesis to Treatment

Paroxysmal Nocturnal Hemoglobinuria (PNH) constitutes a rare bone marrow failure syndrome characterized by hemolytic anemia, thrombotic events (TEs), and bone marrow aplasia of variable degrees.
Tsakiris, Dimitrios A., Grouzi, Elisavet, Valsami, Serena, Evangelidis, Paschalis, Polyviou, Antri, Gavriilaki, Eleni, Gialeraki, Argyri, Tragiannidis, Konstantinos, Kokoris, Styliani   +8 more
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Treatment of paroxysmal nocturnal hemoglobinuria

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, life-threatening hematological disorder characterized by complement-mediated hemolysis, thrombosis, and bone marrow failure.
Cohen, Shay Shalom
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Diagnosis and management of PNH: review and recommendations from a Belgian expert panel.

, 2018
Despite its considerable morbidity and mortality, paroxysmal nocturnal haemoglobinuria (PNH) is still underdiagnosed. Patients with PNH can suffer from cardiovascular, gastro-intestinal, neurological or haematological symptoms and refer to several ...
Boeckx, N, Bérangère Devalet, Gothot, Andre, Nancy Boeckx, Bernard Chatelain, Deeren, Dries, Devalet, Bérangère, Timothy Devos, Meers, Stef, Chatelain, Bernard, Dries Deeren, Devos, T, Meers, S, Gothot, A, Andre Gothot, Chatelain, Christian, Devos, Timothy, Boeckx, Nancy, Christian Chatelain, Deeren, D, Stef Meers   +20 more
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Paroksismal nokturnal hemoglobinüri şüphesi olan hastalarda PNH klonu sıklığının değerlendirilmesi

, 2016
Paroksismal noktürnal hemoglobinüri (PNH), kronik intravasküler hemoliz bulguları, kemik iliği yetersizliği ve trombozla kendini gösteren klonal hemotopoetik kök hücre hastalığıdır.
Suna Bürkük
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Complement drives PNH red cell hemolysis independently of inflammasome activation

Paroxysmal Nocturnal Hemoglobinuria (PNH) is characterized by hemolysis due to the loss of GPI-anchored complement regulators. While terminal complement inhibitors improve survival, the precise intracellular mechanisms driving the destruction of PNH ...
Michael Arthur Cole, Shruti Chaturvedi, Gloria Gerber, Daniel Flores-Guerrero, Nikhil Ranjan, Robert Brodsky   +5 more
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Clinical significance of PNH clones in 3085 patients with cytopenia: a large single-center experience

, 2018
Background Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal disorder due to GPI anchored proteins deficiency on blood cells surface, resulting in complement activation and chronic intravascular hemolysis.
Judith Marsh, Ghulam Mufti, Shireen Kassam, Austin Kulasekararaj, Robin Ireland, Alan Dunlop, Bruno Fattizzo, Deborah Yallop   +7 more
core   +2 more sources

Economic Burden of Paroxysmal Nocturnal Hemoglobinuria (PNH) and Secondary Problems Caused by PNH

Journal of Pharmacoeconomics and Pharmaceutical Management, 2022
Background: Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare, acquired disorder of hematopoietic stem cells, in which red blood cells become susceptible to complement-mediated hemolysis.
Sina Dadfar, Meysam Seyedifar, Sahar Roozbahani, Fatemeh Soleymani   +3 more
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