Results 11 to 20 of about 10,942 (165)
Swiss Survey on current practices and opinions on clinical constellations triggering the search for PNH clones [PDF]
Frontiers in Medicine, 2023 This national survey investigated the current practice in Switzerland by collecting participants' opinions on paroxysmal nocturnal hemoglobinuria (PNH) clone assessment and clinical practice.AimThis study aimed to investigate clinical indications ...
Alicia Rovó +15 more
doaj +3 more sources
DETECTION AND FOLLOW UP OF PNH CLONE BY MEASURING CD55 AND CD59 EXPRESSION ON NEUTROPHILS [PDF]
Zdravniški Vestnik, 2004 Background. Paroxysmal nocturnal haemoglobinuria (PNH) is an acquired clonal haematopoietic stem cell disorder characterised by intravascular haemolysis, bone marrow failure and increased tendency to thrombosis.
Uroš Mlakar, Darja Žontar
doaj +1 more source
"A translational investigastion on unmet clinical needs in PNH" [PDF]
, 2022 Intravascular hemolytic crisis (IVH) triggered by infection and inflammation is a classical clinical feature of Paroxysmal Nocturnal Hemoglobinuria (PNH) and it is an unmet clinical need of PNH patients on complement (C) inhibitors.
Federica Barone
core +1 more source
Insights Into the Emergence of Paroxysmal Nocturnal Hemoglobinuria
Frontiers in Immunology, 2022 Paroxysmal Nocturnal Hemoglobinuria (PNH) is a disease as simple as it is complex. PNH patients develop somatic loss-of-function mutations in phosphatidylinositol N-acetylglucosaminyltransferase subunit A gene (PIGA), required for the biosynthesis of ...
Melissa A. Colden +7 more
doaj +1 more source
Laboratorial characteristics of PNH patients.
, 2023 IntroductionParoxysmal nocturnal hemoglobinuria (PNH) is a clonal disease of hematopoietic cells with a variable clinical spectrum characterized by intravascular hemolysis, high risk of thrombosis, and cytopenias.
Patricia Eiko Yamakawa (16726338) +7 more
core +1 more source
Clinical characteristics of PNH patients.
, 2023 IntroductionParoxysmal nocturnal hemoglobinuria (PNH) is a clonal disease of hematopoietic cells with a variable clinical spectrum characterized by intravascular hemolysis, high risk of thrombosis, and cytopenias.
Patricia Eiko Yamakawa (16726338) +7 more
core +1 more source
Newborn Periventricular Nodular Heterotopia with Persistent Feeding Cyanosis and Apneic Spell: A Case Report [PDF]
Neonatal Medicine, 2022 Periventricular nodular heterotopia (PNH) is a neuronal migration disorder that occurs during early brain development. Patients with PNH may be asymptomatic and have normal intelligence; however, PNH is also known to cause various symptoms such as ...
Seok Jin Hong +5 more
doaj +1 more source
Angewandte Chemie, EarlyView.Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma +5 more
wiley +2 more sources
Hematology, Transfusion and Cell Therapy, 2021 Introduction: Paroxysmal nocturnal hemoglobinuria (PNH) may occur as classical hemolytic disease or a small PNH clone found in a patient with bone marrow failure. Purpose: To describe clinical features and long-term follow-up of 167 patients with PNH and
AP Azambuja +6 more
doaj +1 more source
Pesg PNH diagnosis, follow-up and treatment guidelines
, 2016 PNH Education and Study Group ( PESG) have been established in December 2013 as a non-profit, independent, medical organization www.pesg.org. Paroxysmal Nocturnal Hemoglobinuria ( PNH) is a multi-systemic disease that should be treated with a ...
Ertop, Sehmus +17 more
core +4 more sources