Results 31 to 40 of about 10,942 (165)

Clinicopathological Profile of Paroxysmal Nocturnal Hemoglobinuria among Omani Patients: A Case Series

open access: yesOman Medical Journal, 2022
We aimed to estimate the nature and prevalence of paroxysmal nocturnal hemoglobinuria (PNH) among Omani patients. We performed a retrospective review of all patients who were tested for PNH by flow cytometry at the Sultan Qaboos University Hospital ...
Arwa Z. Al-Riyami   +7 more
doaj   +1 more source

Laboratory studies for paroxysmal nocturnal hemoglobinuria, with emphasis on flow cytometry

open access: yesPractical Laboratory Medicine, 2020
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired clonal hematopoietic stem cell disorder caused by somatic mutations in the PIG-A gene, leading to the production of blood cells with absent or decreased expression of ...
Margarida Lima
doaj   +1 more source

Exploring individualized crovalimab dosing in PNH through in silico modelling: Potential for improved convenience and cost efficiency

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, acquired haematopoietic stem cell disorder. Crovalimab, a complement C5‐inhibitor, is approved for PNH and can be self‐administered subcutaneously every 4 weeks, offering a more convenient route than intravenous C5‐inhibitors.
Mendy ter Avest   +4 more
wiley   +1 more source

Normal and PNH red blood cell (RBC) lysis by 1–12 fold dilutions of normal and PNH serum.

open access: yes, 2014
Serum complement was activated by zymosan. Note that PNH serum, which contained eculizumab, was less active than normal serum. However addition of C5 protein at a final concentration of 100 µg/ml increased PNH RBC lysis to the same levels as control RBCs.
Edith G. McGeer (516358)   +3 more
core   +1 more source

Paroxysmal nocturnal hemoglobinuria: Pandora’s box?

open access: yesJournal of Mind and Medical Sciences, 2020
Introduction. Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired non-malignant hematological disorder which affects the pluripotent hematopoietic stem cell.
Mihnea-Alexandru Găman   +2 more
doaj   +1 more source

THE USE OF COMMERCIAL ENZYMES TO IMPROVE DIETS CONTAINED PEANUT HAY ON PERFORMANCE OF GROWING RABBITS. [PDF]

open access: yesJournal of Animal and Poultry Production, 2008
This experiment was conducted to evaluate the effects of partial or complete replacement of clover hay by PNH (33.3, 66.7 and 100%) with or without adding enzymes in the diets of growing rabbits.
M. Yacout   +3 more
doaj   +1 more source

Economic and environmental implications of the development of UASB reactors in Mexico for sustainable industrial wastewater treatment

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract The objective of this work is to demonstrate that the inclusion of an up‐flow anaerobic sludge bed (UASB reactor) within an industrial wastewater treatment plant reduces the plant's investment and operating costs compared to a system based solely on conventional complete‐mix activated sludge (CMAS), operating under the same design principles ...
Juan Manuel Morgan‐Sagastume   +1 more
wiley   +1 more source

Fetal Hydronephrosis in the Second and Third Trimester of Pregnancy and Six Months Follow-up after Birth [PDF]

open access: yesIranian Journal of Neonatology
Background: Prenatal hydronephrosis (PNH) may be associated with congenital abnormalities in the urinary tract. This study aimed to determine and follow up on the fetus diagnosed with PNH until the first six months after birth.Methods: This prospective ...
Zahra Akbarian-rad   +8 more
doaj   +1 more source

Venous Thromboembolism in Hematologic Malignancies: Incidence, Risk Factors, and the Role of Direct Oral Anticoagulants

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Thrombotic events, particularly venous thromboembolism (VTE), are a significant source of morbidity and mortality among patients with hematologic malignancies. These patients face unique challenges due to treatment‐related complications such as thrombocytopenia, coagulopathy, and heightened bleeding risk.
Mario Biglietto   +12 more
wiley   +1 more source

Cogestão e processo de intervenção de apoiadores da Política Nacional de Humanização em Santa Catarina [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Saúde Coletiva, Florianópolis, 2013.O cenário que se desenhava no campo da saúde no Brasil, segundo a proposta que deu origem à PNH,
Calderon, Daniela Baumgart de Liz
core  

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