LncRNA Binding to Mitochondrial PNPase
Long non-coding RNAs (lncRNAs) are relatively novel RNAs with increasingly prominent roles in regulating genetic expression, mainly in the nucleus but more recently in regions such as the mitochondrion. This study explores how lncRNAs interact with PNPase, a protein that regulates RNA import into the mitochondrion.
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EF-hand protein Ca²⁺ buffers regulate Ca²⁺ influx and exocytosis in sensory hair cells [PDF]
, 2015 EF-hand Ca²⁺-binding proteins are thought to shape the spatiotemporal properties of cellular Ca²⁺ signaling and are prominently expressed in sensory hair cells in the ear.
Gabrielaitis, Mantas +6 more
core
Synchrony of harmony and chaos in a dynamic, bacterial riboregulatory machine [PDF]
In all domains of life, proteins involved in the regulation of RNA lifetimes are often found to form multi-enzyme complexes, suggesting a common requirement to colocalise their activities to meet the demands of RNA metabolism 1,2.
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DEAD Box RhlB RNA Helicase Physically Associates with Exoribonuclease PNPase to Degrade Double-stranded RNA Independent of the Degradosome-assembling Region of RNase E [PDF]
, 2002 Gunn‐Guang Liou +3 more
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A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression [PDF]
, 2017 The p.N478D missense mutation in human mitochondrial poly(A) polymerase (mtPAP) has previously been implicated in a form of spastic ataxia with optic atrophy. In this study, we have investigated fibroblast cell lines established from family members.
Baslé, Arnaud +17 more
core
The Origin of Primitive Cells, Nutrient Intake, and Non-Enzymatic Elongation of Encapsulated Nucleotides [PDF]
Fatty acids and fatty alcohols are commonly found in experiments simulating the prebiotic 'soup'. These amphiphiles can be synthesized under prebiotic conditions, at least as long as the molecules are chemically relatively simple and do not need to be ...
Dworkin, Jason P. +4 more
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Evidence That the P\u3csub\u3ei\u3c/sub\u3e Release Event Is the Rate-Limiting Step in the Nitrogenase Catalytic Cycle [PDF]
, 2016 Nitrogenase reduction of dinitrogen (N2) to ammonia (NH3) involves a sequence of events that occur upon the transient association of the reduced Fe protein containing two ATP molecules with the MoFe protein that includes electron transfer, ATP hydrolysis,
Antony, Edwin +13 more
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Interplay of two small RNAs fine-tunes hierarchical flagella gene expression in Campylobacter jejuni
Nature CommunicationsLike for many bacteria, flagella are crucial for Campylobacter jejuni motility and virulence. Biogenesis of the flagellar machinery requires hierarchical transcription of early, middle (RpoN-dependent), and late (FliA-dependent) genes. However, little is
Fabian König +2 more
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Protein–Protein Interactions between Human Exosome Components Support the Assembly of RNase PH-type Subunits into a Six-membered PNPase-like Ring [PDF]
, 2002 Reinout Raijmakers +3 more
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