Results 141 to 150 of about 5,147 (230)
PLoS Pathogens, 2019 Numerous Gram-negative pathogens use a Type III Secretion System (T3SS) to promote virulence by injecting effector proteins into targeted host cells, which subvert host cell processes.
Maria Kusmierek +8 more
doaj +1 more source
An analytic approximation of the feasible space of metabolic networks
, 2017 Assuming a steady-state condition within a cell, metabolic fluxes satisfy an under-determined linear system of stoichiometric equations. Characterizing the space of fluxes that satisfy such equations along with given bounds (and possibly additional ...
Braunstein, Alfredo +2 more
core +1 more source
BiomoleculesThe exosome multiprotein complex plays a critical role in RNA processing and degradation. This system governs the regulation of mRNA quality, degradation in the cytoplasm, the processing of short noncoding RNA, and the breakdown of RNA fragments.
Seonha Park +7 more
doaj +1 more source
EF-hand protein Ca²⁺ buffers regulate Ca²⁺ influx and exocytosis in sensory hair cells [PDF]
, 2015 EF-hand Ca²⁺-binding proteins are thought to shape the spatiotemporal properties of cellular Ca²⁺ signaling and are prominently expressed in sensory hair cells in the ear.
Gabrielaitis, Mantas +6 more
core
LncRNA Binding to Mitochondrial PNPase
Long non-coding RNAs (lncRNAs) are relatively novel RNAs with increasingly prominent roles in regulating genetic expression, mainly in the nucleus but more recently in regions such as the mitochondrion. This study explores how lncRNAs interact with PNPase, a protein that regulates RNA import into the mitochondrion.
openaire +1 more source
A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression [PDF]
, 2017 The p.N478D missense mutation in human mitochondrial poly(A) polymerase (mtPAP) has previously been implicated in a form of spastic ataxia with optic atrophy. In this study, we have investigated fibroblast cell lines established from family members.
Baslé, Arnaud +17 more
core
PNPase is a key player in the regulation of small RNAs that control the expression of outer membrane proteins [PDF]
, 2008 José M. Andrade, Cecília M. Arraiano
openalex +1 more source
Bacillus subtilis trp Leader RNA: RNase J1 endonuclease cleavage specificity and PNPase processing.
The Journal of biological chemistry, 2009 In the presence of ample tryptophan, transcription from the Bacillus subtilis trp operon promoter terminates to give a 140-nucleotide trp leader RNA. Turnover of trp leader RNA has been shown to depend on RNase J1 cleavage at a single-stranded, AU-rich region just upstream of the 3' transcription terminator.
Gintaras, Deikus, David H, Bechhofer
openaire +1 more source
The Origin of Primitive Cells, Nutrient Intake, and Non-Enzymatic Elongation of Encapsulated Nucleotides [PDF]
Fatty acids and fatty alcohols are commonly found in experiments simulating the prebiotic 'soup'. These amphiphiles can be synthesized under prebiotic conditions, at least as long as the molecules are chemically relatively simple and do not need to be ...
Dworkin, Jason P. +4 more
core +1 more source