Results 121 to 130 of about 47,897 (254)

The protective effect and mechanism of catalpol on high glucose-induced podocyte injury [PDF]

, 2019
Yan Chen, Qingpu Liu, Zengfu Shan, Yingying Zhao, Meng Li, Baiyan Wang, Xiaoke Zheng, Weisheng Feng   +7 more
openalex   +1 more source

Impact of Endothelial Diversity and Dysfunction on Cardiovascular Disease

Comprehensive Physiology, Volume 15, Issue 6, December 2025.
The vascular endothelium is highly diverse, regulating permeability, vascular tone, repair, and inter‐organ communication. Endothelial heterogeneity supports tissue‐specific needs, but dysfunction drives cardiovascular disease. Transcriptomics, in vitro models, and redox signaling studies reveal therapeutic targets for precision treatment of ...
Anna E. Williams, Luke S. Dunaway, Zuzanna J. Juśkiewicz, Wyatt J. Schug, Miriam M. Cortese‐Krott, Michael Koval, Brant E. Isakson   +6 more
wiley   +1 more source

For the eye altering, alters the all [PDF]

, 2015
C
Boey, Olivier, Bogaert, Anne-Marie, De Scheerder, Marie-Angélique, Mahieu, Elien, Vanuytsel, Johan   +4 more
core   +1 more source

Lipid Autophagy: An Idea for the Treatment of Diabetic Nephropathy With Ginseng and Its Active Compounds

eFood, Volume 6, Issue 6, December 2025.
In light of the steadily increasing incidence of diabetic nephropathy (DN), this review explores the potential of edible natural products to slow disease progression, addressing the limitations of conventional clinical drug therapies. Key findings show that ginsenosides, the active compounds in edible ginseng, regulate lipid autophagy, reducing ...
Rui Zhang, Xushan Lan, Chenguang Wu, Jingjing Wang, Chengqian Yin, Lifan Wang, Peng Liu, Ping Li   +7 more
wiley   +1 more source

Effects of BSF on Podocyte Apoptosis via Regulating the ROS-Mediated PI3K/AKT Pathway in DN

Journal of Diabetes Research, 2019
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD). The ROS-mediated PI3K/AKT pathway plays a key role in podocyte apoptosis and DN progression. Our previous study demonstrated that Baoshenfang (BSF) can decrease proteinuria
Fang-qiang Cui, Yue-Fen Wang, Yan-bin Gao, Yuan Meng, Zhen Cai, Cun Shen, Zhi-qiang Liu, Xin-can Jiang, Wen-jing Zhao   +8 more
doaj   +1 more source

CKAP4 in Extracellular Vesicle‐Derived From Podocyte Serves as a Non‐Invasive Diagnostic Biomarker for Diabetic Nephropathy and Promotes Vascular Calcification

Journal of Extracellular Vesicles, Volume 14, Issue 12, December 2025.
CKAP4 in uEVs serves as a robust diagnostic indicator for DN and promotes vascular calcification. ABSTRACT Reliable non‐invasive biomarkers for early detection of diabetic nephropathy (DN), a leading cause of chronic kidney disease, remain limited.
Heng Zhang, Kaibin Lou, Li Qian, Min Zhang, Jie Li, Lizhi Lv, Fang Lu, Guiyang He, Chong Wu, Junxiang Wu, Meng Jia, Yang Bai, Shuang Qu, Meng Liu, Laping Chu, Yangtian Wang, Dafa Ding, Ke Zen, Yanggang Yuan, Hongwei Liang   +19 more
wiley   +1 more source

Cell biology of diabetic nephropathy: Roles of endothelial cells, tubulointerstitial cells and podocytes [PDF]

, 2014
Yoshiro Maezawa, Minoru Takemoto, Koutaro Yokote   +2 more
openalex   +1 more source

#6883 PROTECTIVE ROLE OF THE PODOCYTE IL-15 / STAT5 PATHWAY IN EXPERIMENTAL FOCAL AND SEGMENTAL GLOMERULOSCLEROSIS [PDF]

, 2023
Aïssata Niasse, Kévin Louis, Olivia Lenoir, Laurent Mesnard, Juliette Hadchouel, Yosu Luque   +5 more
openalex   +1 more source

Identification and characterization of novel glomerulus-associated genes and proteins [PDF]

, 2010
The kidney is responsible for sieving the circulating blood to eliminate water-soluble waste products and potentially toxic substances from the body. The filtration step occurs in specialized filtration units called glomeruli.
Xiao, Zhijie
core  

Ovarian Aging: Mechanisms, Age‐Related Disorders, and Therapeutic Interventions

MedComm, Volume 6, Issue 12, December 2025.
A comprehensive overview of the molecular mechanisms underlying ovarian aging, its association with age‐related diseases, and potential therapeutic interventions. Ovarian aging involves DNA damage, mitochondrial dysfunction, oxidative stress, telomere attrition, and follicular depletion, driving age‐related infertility, menopause, and multiple systemic
Xingyu Liu, Yuanqu Zhao, Yanzhi Feng, Shixuan Wang, Jinjin Zhang   +4 more
wiley   +1 more source