Results 111 to 120 of about 33,221 (207)

Activation of podocyte Notch mediates early Wt1 glomerulopathy [PDF]

, 2018
The Wilms' tumor suppressor gene, WT1, encodes a zinc finger protein that regulates podocyte development and is highly expressed in mature podocytes. Mutations in the WT1 gene are associated with the development of renal failure due to the formation of ...
Sebire, NJ, Hohenstein, P, Virasami, AK, Bellerby, J, Moulding, D, Scambler, PJ, Miller-Hodges, EV, Sampson, RD, Waters, AM, Asfahani, R, Tahoun, MM   +10 more
core  

WT-1 (podocyte) staining from STNx rats.

, 2015
As illustrated by representative photomicrographs, in comparison with sham rats (A), STNx rats (B) were associated with a significant increase in podocyte loss.
Elizabeth K. M. Johnstone (711520), Kevin D. G. Pfleger (176476), James H. Williams (489711), Mohammed Akli Ayoub (176430), Robyn S. Kelly (711519), Darren J. Kelly (252497), Heng B. See (587137), Elizabeth A. McCall (711521), Yuan Zhang (41832)   +8 more
core   +1 more source

Podocyte Detachment in Type 2 Diabetic Nephropathy

, 2011
<i>Background:</i> Glomerular podocyte number declines and urinary excretion of podocytes increases as kidney disease progresses in persons with type 2 diabetes mellitus (T2DM). <i>Methods:</i> Using high-power electron microscopy,
Meghan Richardson, Tracy Lovato, E. Jennifer Weil, Berne Yee, Robert G. Nelson, Kevin V. Lemley, Bryan D. Myers   +6 more
core   +1 more source

Podocyte specific knockout of the natriuretic peptide clearance receptor is podocyte protective in focal segmental glomerulosclerosis.

Natriuretic peptides (NPs) bind to glomerular podocytes and attenuate glomerular injury. The beneficial effects of NPs are negatively regulated by the NP clearance receptor (NPRC), which is highly expressed in podocytes.
Anne F Buckley, Yuping Tang, Robert F Spurney, Liming Wang   +3 more
core   +1 more source

Podocyte OTUD5 alleviates diabetic kidney disease through deubiquitinating TAK1 and reducing podocyte inflammation and injury

Recent studies have shown the crucial role of podocyte injury in the development of diabetic kidney disease (DKD). Deubiquitinating modification of proteins is widely involved in the occurrence and development of diseases.
Guang Liang, Wante Lin, Gaojun Wu, Julian Min, Ying Zhao, Zimin Fang, Qingqing Zhao, Diyun Xu, Shijie Fan, Xiang Hu, Liming Lin, Hong Zhu   +11 more
core   +1 more source

Elevated Prorenin Induces Podocyte Injury and Glomerular Fibrosis in cyp1a1-Prorenin Transgenic Rats. [PDF]

Int J Mol Sci
Gu C, Liu X, Wu J, Huang Y.
europepmc   +1 more source

Baseline podocyte-associated state and persistent cell-matrix transcriptional programs are associated with BALB/c substrain differences in adriamycin nephropathy. [PDF]

Animal Model Exp Med
Nakagawa R, Watanabe M, Kawamoto K, Hiratsuka M, Sasaki T, Sasaki N.   +5 more
europepmc   +1 more source

Biallelic pathogenic variants in <i>FLNB</i> are associated with paediatric steroid-resistant nephrotic syndrome via podocyte cytoskeletal dysfunction. [PDF]

J Med Genet
Gan Y, Yang X, Chan H, Yang S, Yang H, Li Q.   +5 more
europepmc   +1 more source

Podocyte [PDF]

, 2020
openaire   +1 more source

A novel redox signalling axis mediates nicotine-induced podocyte injury. [PDF]

Front Pharmacol
Rahman MA, Yellu R, Pavirala V, Datta S, Koka S, Boini KM.   +5 more
europepmc   +1 more source