Results 91 to 100 of about 33,221 (207)

How Many Ways Can a Podocyte Die? [PDF]

, 2012
SummaryPodocytes are highly specialized epithelial cells that line the urinary surface of the glomerular capillary tuft. To maintain kidney filtration, podocytes oppose the high intraglomerular hydrostatic pressure, form a molecular sieve, secrete ...
Huber, Tobias B., Tharaux, Pierre-Louis
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[Podocyte dysfunction and proteinuria] [PDF]

, 2004
Contains fulltext : 58931.pdf (Publisher’s version ) (Open Access)Podocytes play a central role in the pathogenesis of several glomerular diseases.
Berden, J.H.M., Vlag, J. van der, Rietjens, S.J., Vogtländer, N.P.J.   +3 more
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Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses

Cell Reports
Summary: Signal-regulatory protein alpha (SIRPα) has recently been found to be highly expressed in podocytes and is essential for maintaining podocyte function. However, its immunoregulatory function in podocytes remains elusive.
Bin Qian, Rui Lu, Shuya Mao, Yang Chen, Miao Yang, Wenxuan Zhang, Mingchao Zhang, Dihan Zhu, Zhihong Liu, Ke Zen, Limin Li   +10 more
doaj   +1 more source

Influence of Podocyte Injury on the Development of Class IV Lupus Nephritis [PDF]

Cyntia Camilo Franco Borges Zago,1 Bruna de Freitas Oliveira,1 Giovanna Uehara,1 Ana Laura Carvalho da Silva,1 Laura Penna Rocha,1 Fabiano Bichuette Custódio,2 Liliane Silvano Araújo,1 Crislaine Aparecida da Silva,1 Marlene Antônia Reis,1 Juliana Reis ...
Zago CCFB, Uehara G, Reis MA, Custódio FB, Oliveira BDF, Rocha LP, Araújo LS, da Silva CA, Machado JR, da Silva ALC   +9 more
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Reduction of Proteinuria through Podocyte Alkalinization

, 2014
Podocytes are highly differentiated cells and critical elements for the filtration barrier of the kidney. Loss of their foot process (FP) architecture (FP effacement) results in urinary protein loss.
Reiser, Jochen, Altintas, Mehmet M., Moriwaki, Kumiko, Kerjaschki, Dontscho, Yaddanapudi, Suma, Flesche, Jan, Li, Jing, Preston, Richard A, Jiang, Jean X., Huber, Tobias B., Jiang, Jean X, Huber, Tobias B, Altintas, Mehmet M, Möller, Clemens C, Faridi, Mohd Hafeez, Möller, Clemens C., Preston, Richard A., Sever, Sanja, Wei, Changli, Gödel, Markus   +19 more
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Ferroptosis in Podocytes: An Emerging Focus in Kidney Diseases

Biology
Ferroptosis is a mechanism of programmed cell death that is characterized by iron-dependent lipid peroxidation, and it is closely associated with organismal metabolism.
Jun Feng, Yiqiong Ma, Chunyun Zhang
doaj   +1 more source

Activation of podocyte Notch mediates early Wt1 glomerulopathy [PDF]

, 2018
The Wilms' tumor suppressor gene, WT1, encodes a zinc finger protein that regulates podocyte development and is highly expressed in mature podocytes. Mutations in the WT1 gene are associated with the development of renal failure due to the formation of ...
Tahoun, Mona M., Robert D. Sampson, Mona M. Tahoun, Alex K. Virasami, Miller-Hodges, Eve V., Asfahani, Rowan I., Hohenstein, Peter, Peter J. Scambler, Moulding, Dale, Sebire, Neil J., Aoife M. Waters, Neil J. Sebire, Waters, Aoife M., Rowan I. Asfahani, Dale Moulding, Virasami, Alex K., Jack Bellerby, Bellerby, Jack, Eve V. Miller-Hodges, Sampson, Robert D., Scambler, Peter J., Peter Hohenstein   +21 more
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Targeting podocyte-associated diseases☆

, 2010
Injury to the podocytes is the initiating cause of many renal diseases, leading to proteinuria with possible progression to end-stage renal disease. Podocytes are highly specialized cells, with an important role in maintaining the glomerular filtration ...
Jan Willem Leeuwis, Tri Q. Nguyen, Nguyen, Tri Q., Amélie Dendooven, Kok, Robbert J., Goldschmeding, Roe, Robbert J. Kok, Roel Goldschmeding, Leeuwis, Jan Willem, Dendooven, Amélie   +9 more
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Podocytes [PDF]

The American Journal of Pathology, 2020
Marica Giliberti, Adele Mitrotti, Loreto Gesualdo   +2 more
openaire   +1 more source

REGULATION OF PODOCYTE DEVELOPMENT INXENOPUS

, 2010
Podocytes are highly specified cells present in the glomus/glomerulus of vertebrate kidney. They are part of a size-exclusion barrier and crucial for the kidney function. Defects in podocyte always cause for the loss of kidney function.
White, Jeffrey, Zhang, Bo, Tran, Uyen, Cerqueira, Debora   +3 more
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