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Focal segmental glomerulosclerosis associated with long-term treatment with zoledronate in a myeloma patient [PDF]

open access: yes, 2017
Amico, Patrizia   +6 more
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Aldosterone and glomerular podocyte injury

Clinical and Experimental Nephrology, 2008
Aldosterone is traditionally viewed as a hormone regulating electrolyte and blood pressure homeostasis by acting on the distal nephron. Accumulating evidence suggests that aldosterone also plays pathogenetic roles in cardiovascular and renal injury. For example, aldosterone is a potent inducer of proteinuria.
Miki, Nagase, Toshiro, Fujita
openaire   +2 more sources

Parthenolide ameliorates tweak-induced podocytes injury

Molecular Biology Reports, 2020
Parthenolide (PTL) is a natural product from the shoots of Tanacetum parthenium, which has immunomodulatory effects in multiply type of diseases. This study aimed to explore the effect and the underlying mechanism of PTL on the anti-apoptotic and anti- inflammatory ability of tweak-induced podocytes.
Lichun Yu   +5 more
openaire   +2 more sources

Urinary Biomarkers of Podocyte Injury

Biomarkers in Medicine, 2008
Podocyturia may be an expression of glomerular disease and is evaluated using urinary podocyte-specific molecules. This article discusses the technical problems of detection and quantification of podocyturia using immunofluorescent staining of specific proteins, urinary podocyte culture, flow cytometry and urinary podocyte-specific molecules (including
openaire   +3 more sources

Podocyte Injury in FSGS

2014
Background: The podocyte is central to the glomerular filtration barrier and is particularly important in the disease process of focal segmental glomerulosclerosis (FSGS). The podocyte is injured in two main ways in idiopathic nephrotic syndrome. The first is by single gene disorders, such as NPHS1, NPHS2, CD2AP and TRPC6, which has led to a focus on ...
Wen Yi Ding, Moin A. Saleem
openaire   +1 more source

Immunohistochemical and urinary markers of podocyte injury

Pediatric Nephrology, 1998
Renal podocytes play an important role in glomerular filtration. We estimated podocyte injury by light microscopic examination of kidney specimens or by urinary excretion of substances related to podocytes. Fresh kidney sections from 69 patients and urinary sediments from 84 patients with various renal diseases were examined immunohistochemically using
M, Hara   +4 more
openaire   +2 more sources

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