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Development of a Multiplexed LC-MS/MS Assay for the Quantitation of Podocyte Injury Biomarkers Nephrin, Podocalyxin, and Podocin in Human Urine. [PDF]
Morales-Betanzos CA +4 more
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Focal segmental glomerulosclerosis associated with long-term treatment with zoledronate in a myeloma patient [PDF]
Amico, Patrizia +6 more
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THSD7A-associated membranous nephropathy involves both complement-mediated and autonomous podocyte injury. [PDF]
Liu J +5 more
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Aldosterone and glomerular podocyte injury
Clinical and Experimental Nephrology, 2008Aldosterone is traditionally viewed as a hormone regulating electrolyte and blood pressure homeostasis by acting on the distal nephron. Accumulating evidence suggests that aldosterone also plays pathogenetic roles in cardiovascular and renal injury. For example, aldosterone is a potent inducer of proteinuria.
Miki, Nagase, Toshiro, Fujita
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Parthenolide ameliorates tweak-induced podocytes injury
Molecular Biology Reports, 2020Parthenolide (PTL) is a natural product from the shoots of Tanacetum parthenium, which has immunomodulatory effects in multiply type of diseases. This study aimed to explore the effect and the underlying mechanism of PTL on the anti-apoptotic and anti- inflammatory ability of tweak-induced podocytes.
Lichun Yu +5 more
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Urinary Biomarkers of Podocyte Injury
Biomarkers in Medicine, 2008Podocyturia may be an expression of glomerular disease and is evaluated using urinary podocyte-specific molecules. This article discusses the technical problems of detection and quantification of podocyturia using immunofluorescent staining of specific proteins, urinary podocyte culture, flow cytometry and urinary podocyte-specific molecules (including
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2014
Background: The podocyte is central to the glomerular filtration barrier and is particularly important in the disease process of focal segmental glomerulosclerosis (FSGS). The podocyte is injured in two main ways in idiopathic nephrotic syndrome. The first is by single gene disorders, such as NPHS1, NPHS2, CD2AP and TRPC6, which has led to a focus on ...
Wen Yi Ding, Moin A. Saleem
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Background: The podocyte is central to the glomerular filtration barrier and is particularly important in the disease process of focal segmental glomerulosclerosis (FSGS). The podocyte is injured in two main ways in idiopathic nephrotic syndrome. The first is by single gene disorders, such as NPHS1, NPHS2, CD2AP and TRPC6, which has led to a focus on ...
Wen Yi Ding, Moin A. Saleem
openaire +1 more source
Immunohistochemical and urinary markers of podocyte injury
Pediatric Nephrology, 1998Renal podocytes play an important role in glomerular filtration. We estimated podocyte injury by light microscopic examination of kidney specimens or by urinary excretion of substances related to podocytes. Fresh kidney sections from 69 patients and urinary sediments from 84 patients with various renal diseases were examined immunohistochemically using
M, Hara +4 more
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