Results 81 to 90 of about 19,338 (290)

Lymphangiogenesis and angiogenesis during human fetal pancreas development [PDF]

, 2014
Background: The complex endocrine and exocrine functionality of the human pancreas depends on an efficient fluid transport through the blood and the lymphatic vascular systems. The lymphatic vasculature has key roles in the physiology of the pancreas and
Carlotti, Françoise, Chuva de Sousa Lopes, Susana Marina, de Koning, Eelco JP, de Melo Bernardo, Ana, Mummery, Christine L, Roost, Matthias S, van Iperen, Liesbeth   +6 more
core   +1 more source

CLEC-2 and podoplanin, partners again [PDF]

Blood, 2016
In this issue of Blood, Tamura et al reveal a novel function for podoplanin on periarteriolar stromal cells in the bone marrow: promoting megakaryocyte growth and proplatelet formation by interaction with C-type lectin-like receptor 2 (CLEC-2).
Jianxin Fu, Lijun Xia
openaire   +3 more sources

Prognostic value of podoplanin expression in intratumoral stroma and neoplastic cells of uterine cervical carcinomas

Clinics, 2010
OBJECTIVE: To investigate the clinicopathological significance of podoplanin expression in the intratumoral stroma and neoplastic cells of early stage uterine cervical cancer.
Filomena M Carvalho, Fabricia L Zaganelli, Bernardo G L Almeida, Joao Carlos Sampaio Goes, Edmund C Baracat, Jesus P Carvalho   +5 more
doaj   +1 more source

Novel circulating tumor cell-detection chip combining conventional podoplanin and EGFR antibodies for all histological malignant pleural mesothelioma

Oncology Letters, 2021
In our previous study, a microfluidic system was developed based on podoplanin detection for capturing circulating tumor cells (CTCs), derived from malignant pleural mesothelioma (MPM). However, non-epithelioid MPM shows low podoplanin protein expression
Masatoshi Kanayama, Rintaro Oyama, Masataka Mori, A. Taira, S. Shinohara, T. Kuwata, M. Takenaka, K. Yoneda, K. Kuroda, Takashi Ohnaga, Y. Kato, F. Tanaka   +11 more
semanticscholar   +1 more source

Der Einfluss endogener und exogener Faktoren auf Podozyten und Nierenfunktion [PDF]

, 2018
Einleitung: Humane Podozyten (hPC) stellen hochdifferenzierte Zellen dar, die einen elementaren Bestandteil der renalen Filtrationsbarriere bilden. Ihre intensive Erforschung in vitro ist erst seit wenigen Jahren möglich.
Langer, Sebastian
core   +1 more source

Prospective validation of podoplanin expression as a diagnostic biomarker of acute promyelocytic leukemia

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva, Carla Roberta Peachazepi Moraes, Bruno Kosa Lino Duarte, Gislaine Borba Oliveira, Herton Luiz Alves Sales Filho, Paula de Melo Campos, Sara Teresinha Olalla Saad, Erich Vinicius De Paula   +7 more
wiley   +1 more source

Novel Combination of Surface Markers for the Reliable and Comprehensive Identification of Human Thymic Epithelial Cells by Flow Cytometry: Quantitation and Transcriptional Characterization of Thymic Stroma in a Pediatric Cohort

Frontiers in Immunology, 2021
Thymic epithelial cells (TECs) are essential in supporting the development of mature T cells from hematopoietic progenitor cells and facilitate their lineage-commitment, proliferation, T-cell receptor repertoire selection and maturation.
Veronika Haunerdinger, Maria Domenica Moccia, Lennart Opitz, Stefano Vavassori, Hitendu Dave, Mathias M. Hauri-Hohl   +5 more
doaj   +1 more source

Targeted Phototherapy for Malignant Pleural Mesothelioma: Near-Infrared Photoimmunotherapy Targeting Podoplanin

Cells, 2020
Malignant pleural mesothelioma (MPM) has extremely limited treatment despite a poor prognosis. Moreover, molecular targeted therapy for MPM has not yet been implemented; thus, a new targeted therapy is highly desirable.
Yuko Nishinaga, Kazuhide Sato, H. Yasui, S. Taki, Kazuomi Takahashi, Misae Shimizu, Rena Endo, Chiaki Koike, Noriko Kuramoto, S. Nakamura, T. Fukui, H. Yukawa, Y. Baba, Mika K. Kaneko, T. Chen-Yoshikawa, Hisataka Kobayashi, Y. Kato, Y. Hasegawa   +17 more
semanticscholar   +1 more source

T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions. [PDF]

, 2017
T cells are the most abundant cell type found in afferent lymph, but their migration through lymphatic vessels (LVs) remains poorly understood. Performing intravital microscopy in the murine skin, we imaged T cell migration through afferent LVs in vivo ...
Coles, Marc, Debes, Gudrun F., Detmar, Michael, Frei, Thomas, Halin, Cornelia, Hunter, Morgan C., Melero, Ignacio, Proulx, Steven T, Rouzaut, Ana, Russo, Erica, Teijeira, Alvaro   +10 more
core   +3 more sources

Malignant Transformation of Oral Leukoplakia and Proliferative Verrucous Leukoplakia and Its Biomarker Predictors: A Systematic Umbrella Review

Head &Neck, EarlyView.
ABSTRACT Background Oral leukoplakia (OL) represents the most common oral potentially malignant disorder globally, with highly variable reported malignant transformation (MT) rates creating challenges for evidence‐based clinical management. Objective To systematically synthesize evidence on MT prevalence in OL and evaluate potential predictive ...
Mohammed Taib Fatih, Mohammed Khalid Mahmood, Balkees Taha Garib, Yad Mariwan Mohammed Amin, Ranjdar Mahmood Talabani, Tara Ali Rasheed, Handren Ameer Kurda, Balen Hamid Qadir, Zana Fuad Noori, Mohammed Aso Abdulghafor, Ariwan Othman Saeed, Herve Tassery, Delphine Tardivo, Romain Lan   +13 more
wiley   +1 more source