Results 61 to 70 of about 11,879 (214)

Biomarkers Correlating With the Development of Oral Squamous Cell Carcinoma From Leukoplakia

Oral Diseases, EarlyView.
ABSTRACT Background We assessed protein biomarkers expressed in oral leukoplakia (OL) that are associated with the risk of transformation into oral squamous cell carcinoma (OSCC). Methods Tissue sections of OL transforming into OSCC (leuko‐ca), the corresponding OSCC and OL that did not progress to OSCC (leuko‐nonca) were analyzed with global relative ...
Daniel Giglio, Divya Ganesh, Bishwa Prakash Bhattarai, Tine Merete Søland, Jonas Sundberg, Annika Thorsell, Jenny Öhman, Dipak Sapkota, Bengt Hasséus   +8 more
wiley   +1 more source

The role of podoplanin in cutaneous wound healing [PDF]

, 2011
Die vorliegende Arbeit befasst sich mit der Funktion welche Podoplanin, ein 43kDa mucin-artiges transmembranes Sialoglycoprotein während der kutanen Wundheilung erfüllt.
Koban, Florian
core  

Mouse podoplanin supports adhesion and aggregation of platelets under arterial shear: A novel mechanism of haemostasis

Platelets, 2018
The podoplanin-CLEC-2 axis is critical in mice for prevention of hemorrhage in the cerebral vasculature during mid-gestation. This raises the question as to how platelets are captured by podoplanin on neuroepithelial cells in a high shear environment. In
Stephanie E. Lombard, Alice Y. Pollitt, Craig E. Hughes, Ying Di, Tom Mckinnon, Chris A. O’callaghan, Steve P. Watson   +6 more
doaj   +1 more source

TNFSF14/LIGHT responses in intestinal and oesophageal fibroblasts are differentially modulated by hydroxylase inhibitors

The Journal of Physiology, EarlyView.
Abstract figure legend LIGHT is a mutual mediator of intestinal and oesophageal fibroblast inflammation with common as well as tissue‐specific effects. Hydroxylase inhibitors can selectively suppress inflammatory factors in both cell types, albeit targeting different signalling pathways.
Cian M. Ohlendieck, Carlos Matellan, Cristina Bauset, Bella Raphael, Mary Nwaezeigwe, Emer Flynn, Kevin Okamoto, Desmond Winter, Colm Collins, Katie Doogan, Seán T. Martin, Glen Doherty, Seema S. Aceves, Mario C. Manresa   +13 more
wiley   +1 more source

Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2

Retrovirology, 2010
Background Platelets are associated with HIV in the blood of infected individuals and might modulate viral dissemination, particularly if the virus is directly transmitted into the bloodstream.
Münch Jan, Schmökel Jan, Kato Yukinari, Glowacka Ilona, Bertram Stephanie, Tsegaye Theodros, Steffen Imke, Chaipan Chawaree, Simmons Graham, Gerardy-Schahn Rita, Pöhlmann Stefan   +10 more
doaj   +1 more source

Maternal protein restriction programs the ageing kidney: Proteomic signatures of early‐life origin renal and metabolic dysfunction

The Journal of Physiology, EarlyView.
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires, Matheus Naia Fioretto, Marcel Rodrigues Ferreira, Isabelle Tenori Ribeiro, Luísa Annibal Barata, Flávia Alessandra Maciel, Lucas Sobrinho Lemos, Renato Mattos, Luiz Marcos Frediane Portela, Patrick Vieira de Souza, Luisa Correia Gomes, Gustavo Monezzi Cordeiro, Wellerson Rodrigo Scarano, Patrícia Aline Boer, Jose Antonio Rocha Gontijo, Luis Antonio Justulin   +15 more
wiley   +1 more source

Role of podoplanin expression in deciding the invasive potential of ameloblastoma – A retrospective IHC study

Journal of Oral Biology and Craniofacial Research, 2016
Background: The aim of this study was to investigate the podoplanin expression in epithelial odontogenic tumors both non-aggressive and aggressive, tumors with and without ectomesenchyme and remnants of the odontogenic epithelium from dental follicles ...
Sindhu M. Ganvir, Pratima G. Khobragade, Swati A. Bamane, Ramnivas Kumavat, Amit Dalmia   +4 more
doaj   +1 more source

Enrichment and Proteomic Profiling of Stromal‐Associated Extracellular Vesicle Subpopulations From Arthritic Synovial Fluid by Size‐Exclusion Chromatography Coupled to CD90‐Directed Immunocapture

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Synovial fluid contains heterogeneous EV populations reflecting stromal and immune‐associated cellular inputs from the arthritic joint. SEC‐UF enrichment coupled to CD90‐targeted immunocapture enables recovery of stromal‐associated EV subpopulation from complex patient synovial fluid, while focused LC‐MS/MS and cell‐of‐origin analysis enable molecular ...
Stefanie Kurth, Edveena Hanser, Simone Häner‐Massimi, Stavros Giaglis, Florian Geier, Dominik Burri, Katarzyna Buczak, Ute Heider, Stefan Wild, Yves P. Acklin, Christian Egloff, André N. Tiaden, Diego Kyburz   +12 more
wiley   +1 more source

Is podoplanin expression associated with the proliferative activity of ameloblastomas?

, 2012
Oral Diseases (2012) 18, 673679 Objectives: The aim of this study was to investigate the relationship between podoplanin expression and proliferative activity of ameloblastomas and remnants of the odontogenic epithelium from dental follicles (DF) of ...
Lauris, J. R. P., Oliveira, D. T., Soares, C. T., Damante, J. H., Tjioe, K. C.   +4 more
core   +1 more source

Podoplanin-Fc burns out platelets [PDF]

Blood, 2010
In this issue of Blood, Cueni and colleagues have demonstrated that podoplanin-Fc not only displays an inhibitory effect on lymphatic vessel formation, but also induces platelet aggregation and disseminated intravascular coagulation (DIC) in transgenic mice.
Kim, HS Kim, Hon-Soul, Koh, GY Koh, Gou-Young   +1 more
openaire   +3 more sources