Results 121 to 130 of about 10,528,066 (300)
Dark Energy Survey Year 6 Results: Point-Spread Function Modeling
We present the point-spread function (PSF) modeling for weak lensing shear measurement using the full six years of the Dark Energy Survey (DES Y6) data.
T. Schutt +73 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Aperture Photometric Accuracy of Point-spread-function-deconvolved Astronomical Images
This paper introduces an improved Richardson–Lucy (RL) framework utilizing negative backfilling (NB) and the novel filtered image deconvolution and noise backfilling (FiDNoBa) algorithm. By integrating a low-pass prefiltering stage—specifically employing
Shen Zhang +13 more
doaj +1 more source
Study of the Properties of Image Formation by an Optical System Consisting of a Diffractive Lens
Diffractive lenses form images based on the principle of light diffraction, unlike conventional lenses that rely on the phenomenon of refraction to form images.
Raghda Z. Khuder, Alaa B. Hasan
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A Novel 3D Probe for Near-Field Scanning Microwave Microscopy
Near-field scanning microwave microscopy (NSMM) offers the ability to probe local electromagnetic properties beyond the classical Abbe diffraction limit, but achieving high resolution over practical scan areas remains challenging.
Ali M. Almuhlafi, Omar M. Ramahi
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

