Results 61 to 70 of about 187,835 (253)

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Utilization of the point load index method as an estimator of rock compressive strength in civil engineering [PDF]

E3S Web of Conferences
Lawa Cave is one of the geotourism sites located in Purbalingga, Central Java, specifically on the eastern slope of Mount Slamet. The large number of tourists visiting each year and the construction of several buildings inside the cave necessitate an ...
Asih Andrea Sumarah, Astuti Bernadeta Subandini   +1 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

STRUCTURAL STRENGTH ANALYSIS AND EXPERIMENTAL RESEARCH FOR WORKING DEVICE OF LOADER

Jixie qiangdu, 2016
In order to obtain the positions of load spectrum measuring points of the loader working device,the structural strength and fatigue strength of the working device were evaluated.
WAN YiPin, JIA Jie, LIANG Jia, SONG XuDing   +3 more
doaj  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A study on surrounding rock characteristics inducing severe large deformation in tunnels and methods for determining its strength

Scientific Reports
The Haba Snow Mountain Tunnel experienced severe deformation caused by foliated metamorphic basalt. This rock has high metamorphism, easy weathering, and low strength.
Zhongsheng Tan, Jinpeng Zhao, Zonglin Li, Baojin Zhang   +3 more
doaj   +1 more source

Velocity effects on slip evolution of faults subjected to constant and cyclic normal stress derived from laboratory tests

Rock Mechanics Bulletin
Understanding the slip-style evolution of tectonic faults is important for exploring the earthquake mechanisms. To reveal the fault slip characteristics under a complex stress state, we conducted a series of laboratory friction tests on saw-cut granite ...
Kang Tao, Wengang Dang, Heinz Konietzky, Yu Liu, Wenhao Zhang, Xingling Li   +5 more
doaj   +1 more source

Experimental Study on the Effect of Offset Notch on Fracture Properties of Rock under Three-Point Bending Beam

Advances in Materials Science and Engineering, 2020
To investigate the effects of offset notch on the fracture properties of rock beam under bending load, granite beam specimens with “one single offset notch” and “central and offset double notches” are made.
Qifeng Guo, Xinghui Wu, Meifeng Cai, Shengjun Miao   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source