Results 61 to 70 of about 7,295,630 (273)

The Effects of Adding Attachments in Conventional Composite Hybrid Joints on Tensile Strength [PDF]

, 2010
Mechanical fasteners are commonly used in today’s composite aircraft adhesive joints. The primary purpose for using mechanical fasteners was to provide redundancy to the adhesive joints because of the uncertainties associated with an adhesive only joint.
Wang, Peng Hao
core   +1 more source

Numerical Investigations of Small Punch Tests for Determining Tensile Properties

Ubiquity Proceedings, 2018
Small punch tests were conducted for carbon steel specimens prepared with and without cold working. A digital image correlation technique was applied to measure displacement.
M. Kamaya
doaj   +1 more source

History-sensitive accumulation rules for life-time prediction under variable loading [PDF]

, 2011
This is the post-print version of the article. The official published version can be obtained from the link below - Copyright @ 2011 SpringerA general form of temporal strength conditions under variable creep loading is employed to formulate several new ...
Mikhailov, SE, S. E. Mikhailov, I. V. Namestnikova, Namestnikova, IV   +3 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Effect of Indenter Angle on Bearing Performance of Coal and Accompanying Rocks Under Point Load and Characterization of Mechanical Parameters

Energy Science & Engineering
Coal, mudstone, sandstone, and limestone, which are common in coal mines, were selected as research objects, and 60°, 90°, and 120° indenters were used to conduct point load tests to study the deformation and failure laws of rocks under point loads. This
Qian Wang, Yujiang Zhang, Delong Cui, Guorui Feng, Yunlou Du, Shuai Zhang, Haojie Cheng, Zhengjun Zhang   +7 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Stress-State-Based Failure Analysis and Modeling of UHPC Columns Confined with High-Strength Spiral Stirrups

Buildings
This study investigated the failure mechanism and load-bearing capacity of ultra-high-performance concrete (UHPC) columns confined with high-strength spiral stirrups under axial compression. Based on tests of 75 specimens, a structural stability analysis
Yan Zhao, Xiong Xie, Zhen Xu, Min Zhang, Xiaotian Lin, Wei Chang   +5 more
doaj   +1 more source

Point Load Test of Half-Cylinder Core Using the Numerical Model and Laboratory Tests: Size Suggestion and Correlation with Cylinder Core

Advances in Civil Engineering, 2018
The point load test (PLT) is intended as an index test for rock strength classification or estimations of other strength parameters because it is economical and simple to conduct in the laboratory and in field tests.
Fengyu Ren, Huan Liu, Rongxing He, Guanghui Li, Yang Liu   +4 more
doaj   +1 more source

Effects of weld bonding on bending performance and axial compression performance of hat-shaped members

Nihon Kikai Gakkai ronbunshu, 2016
This paper discusses the effects of weld bonding for flanges on the 3-point bending strength and axial compression strength of high strength hat-shaped steel sheet members. The effects of weld bonding were different depending on the loading direction and
Hiroki FUJIMOTO, Hideki UEDA
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source