Results 11 to 20 of about 6,527,208 (145)

Elastin genetic point mutation and the risk of pelvic organ prolapse

open access: yesClinical and Experimental Obstetrics & Gynecology, 2020
Aim: A missense mutation in the elastin gene (g28197A > G) is associated with an increased risk for inguinal hernias. Due to the shared epidemiological and pathophysiological features between pelvic organ prolapse (POP) and inguinal hernias, the authors ...
N. Haya   +5 more
doaj   +1 more source

Types of 23S Ribosomal RNA Point Mutations and Therapeutic Outcomes for Helicobacter pylori

open access: yesGut and Liver, 2021
Background/Aims: Point mutations in the 23S ribosomal RNA gene have been associated with Helicobacter pylori clarithromycin resistance. This study aimed to detect the prevalence of these point mutations and to investigate the role of different point ...
Sang Yoon Kim   +7 more
doaj   +1 more source

Effectiveness of 7-day triple therapy with half-dose clarithromycin for the eradication of Helicobacter pylori without the A2143G and A2142G point mutations of the 23S rRNA gene in a high clarithromycin resistance area

open access: yesFrontiers in Medicine, 2023
BackgroundTailored therapy has been widely used for patients with Helicobacter pylori (H. pylori) infection in South Korea. Herein, we evaluated the treatment outcomes of tailored clarithromycin-based triple therapy (TT) in patients infected with H ...
Seong Hyun Cho   +5 more
doaj   +1 more source

Recombinant Escherichia coli BL21 with LngA Variants from ETEC E9034A Promotes Adherence to HT-29 Cells

open access: yesPathogens, 2023
The CS21 pilus produced by enterotoxigenic Escherichia coli (ETEC) is involved in adherence to HT-29 intestinal cells. The CS21 pilus assembles proteins encoded by 14 genes clustered into the lng operon. Aim. This study aimed to determine whether E. coli
Karina Espinosa-Mazariego   +9 more
doaj   +1 more source

Pyruvic Acid Production from Sucrose by Escherichia coli Pyruvate Dehydrogenase Variants

open access: yesFermentation, 2023
Sucrose is an abundant, cheap, and renewable carbohydrate which makes it an attractive feedstock for the biotechnological production of chemicals. Escherichia coli W, one of the few safe E.
W. Chris Moxley, Mark A. Eiteman
doaj   +1 more source

[Point mutation].

open access: yesNihon rinsho. Japanese journal of clinical medicine, 2019
A point mutation is when a single base pair is altered. Point mutations can have one of three effects. First, the base substitution can be a silent mutation where the altered codon corresponds to the same amino acid.
Y. Yuasa
semanticscholar   +1 more source

Dominant point mutation in a tetraspanin gene associated with field-evolved resistance of cotton bollworm to transgenic Bt cotton

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Crops genetically engineered to produce insecticidal proteins from the bacterium Bacillus thuringiensis (Bt) kill some major pests and reduce use of insecticide sprays.
Lin Jin   +14 more
semanticscholar   +1 more source

OsCIPK7 point-mutation leads to conformation and kinase-activity change for sensing cold response.

open access: yesJournal of Integrative Plant Biology, 2019
Calcineurin B-like interacting protein kinases (CIPKs) play important roles via environmental stress. However, less is known how to sense the stress in molecular structure conformation level.
Dajian Zhang   +9 more
semanticscholar   +1 more source

Target-Site Mutations and Glutathione S-Transferases Are Associated with Acequinocyl and Pyridaben Resistance in the Two-Spotted Spider Mite Tetranychus urticae (Acari: Tetranychidae)

open access: yesInsects, 2020
The two-spotted spider mite Tetranychus urticae is a difficult-to-control pest due to its short life cycle and rapid resistance development. In this study, we characterized field strains collected in 2001 and 2003 that were selected for acequinocyl ...
Jihye Choi   +5 more
doaj   +1 more source

STRUM: structure-based prediction of protein stability changes upon single-point mutation

open access: yesBioinform., 2016
MOTIVATION Mutations in human genome are mainly through single nucleotide polymorphism, some of which can affect stability and function of proteins, causing human diseases.
Lijun Quan, Q. Lv, Yang Zhang
semanticscholar   +1 more source

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