Results 51 to 60 of about 6,527,208 (145)

Repeat-induced point mutation (RIP) as an alternative mechanism of evolution toward virulence in Leptosphaeria maculans.

open access: yesMolecular Plant-Microbe Interactions, 2009
Three avirulence genes, AvrLm1, AvrLm6, and AvrLm4-7, were recently identified in Leptosphaeria maculans and found to be localized as solo genes within large noncoding, heterochromatin-like regions mainly composed of retrotransposons, truncated and ...
I. Fudal   +7 more
semanticscholar   +1 more source

The Ser431Phe substitution in acetylcholinesterase associated with pirimicarb and organophosphorous insecticide resistance in the peach-potato aphid, Myzus persicae (Hem.: Aphididae) [PDF]

open access: yesنامه انجمن حشره‌شناسی ایران, 2010
The peach-potato aphid, Myzus pesicae Sulzer, is a globally distributed, economically important pest of a wide range of field crops and ornamentals. Due to extensive and repeated use of insecticide, this species has developed many different resistance ...
Y. Kono, Kh. Talebi, M. Ghadamyari
doaj  

Widespread Distribution of a Newly Found Point Mutation in Voltage-Gated Sodium Channel in Pyrethroid-Resistant Aedes aegypti Populations in Vietnam

open access: yesPLoS Neglected Tropical Diseases, 2009
Background Resistance of Aedes aegypti to photostable pyrethroid insecticides is a major problem for disease-vector control programs. Pyrethroids target the voltage-gated sodium channel on the insects' neurons.
H. Kawada   +8 more
semanticscholar   +1 more source

A Point Mutation in Sec61α1 Leads to Diabetes and Hepatosteatosis in Mice

open access: yesDiabetes, 2009
OBJECTIVE Type 2 diabetes is caused by both environmental and genetic factors. To better understand the genetic factors we used forward genetics to discover genes that have not previously been implicated in the development of hyperglycemia or diabetes ...
David J. Lloyd   +2 more
semanticscholar   +1 more source

Characterisation of the macular dystrophy in patients with the A3243G mitochondrial DNA point mutation with fundus autofluorescence

open access: yesBritish Journal of Ophthalmology, 2008
Introduction: The mitochondrial DNA A3243G point mutation is associated with a wide variety of systemic manifestations including a macular dystrophy. The characteristics of fundus autofluorescence (AF) in these patients are distinctive and have not been ...
P. P. Rath   +7 more
semanticscholar   +1 more source

Detection of HIV cDNA Point Mutations with Rolling-Circle Amplification Arrays

open access: yesMolecules, 2010
In this paper we describe an isothermal rolling-circle amplification (RCA) protocol to detect gene point mutations on chips. The method is based on an allele-specific oligonucleotide circularization mediated by a special DNA ligase.
Zhongwei Wu   +3 more
doaj   +1 more source

The Mutation Glu151Asp in the B-Component of the Bacillus cereus Non-Hemolytic Enterotoxin (Nhe) Leads to a Diverging Reactivity in Antibody-Based Detection Systems

open access: yesToxins, 2015
The ability of Bacillus cereus to cause foodborne toxicoinfections leads to increasing concerns regarding consumer protection. For the diarrhea-associated enterotoxins, the assessment of the non-hemolytic enterotoxin B (NheB) titer determined by a ...
Andrea Didier   +5 more
doaj   +1 more source

Detecting somatic point mutations in cancer genome sequencing data: a comparison of mutation callers

open access: yesGenome Medicine, 2013
Driven by high throughput next generation sequencing technologies and the pressing need to decipher cancer genomes, computational approaches for detecting somatic single nucleotide variants (sSNVs) have undergone dramatic improvements during the past 2 ...
Qingguo Wang   +8 more
semanticscholar   +1 more source

Development of a Novel Loop-Mediated Isothermal Amplification Method to Detect Guiana Extended-Spectrum (GES) β-Lactamase Genes in Pseudomonas aeruginosa

open access: yesFrontiers in Microbiology, 2019
Infections caused by multidrug-resistant Pseudomonas aeruginosa in hospitalized patients are often fatal, and nosocomial infections caused by Guiana extended-spectrum (GES) β-lactamase-producing strains are of growing concern.
Chika Takano   +9 more
doaj   +1 more source

Detection of Mutations of Antimutator Gene pfpI in Pseudomonas aeruginosa Species Isolated from Burn Patients in Tehran, Iran

open access: yesJournal of Medical Microbiology and Infectious Diseases, 2019
Introduction: Pseudomonas aeruginosa is an opportunistic pathogen of clinical importance, particularly in immunocompromised and burn patients. This bacterium is becoming resistant to many antibiotics via intrinsic or acquired mechanisms.
Maryam Khalili-Samani   +4 more
doaj  

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