Results 71 to 80 of about 5,667,138 (292)
Mutations and Pointing for Brauer Tree Algebras
Osaka Journal of Mathematics, 2016 11 Figures. Version 2 is shorter, has some minor errors corrected, and contains a theorem relating the Aihara Algorithm to the Rickard tree-to-star complex with the left alternating pointing, which was not in version ...
Schaps, Mary, Zvi, Zehavit
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Helical ambivalency induced by point mutations [PDF]
BMC Structural Biology, 2013 Mutation of amino acid sequences in a protein may have diverse effects on its structure and function. Point mutations of even a single amino acid residue in the helices of the non-redundant database may lead to sequentially identical peptides which adopt different secondary structures in different proteins.
Bhattacharjee, Nicholus, Biswas, Parbati
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Disease Models & Mechanisms, 2020 Friedreich's ataxia (FRDA) is an autosomal recessive neurodegenerative disease caused by reduced expression of the mitochondrial protein frataxin (FXN).
Daniel Fil +9 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Mutation in Rh48: Assessment for possible mutation prone point [PDF]
Indian Journal of Hematology and Blood Transfusion, 2010 Rh antigen is a widely studied but not already known antigen. RH48 (JAL) is a low-incidence Rh antigen of unknown molecular background and is proposed for association with weakened expression of RhCE antigens. Here, the author performed a bioinformatics approach to study the probability of JAL mutation.
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Central Point Notice of Adopted Amendment (2008-12-29) [PDF]
, 2008 162 pp. Adopted 2008-12-29. Department of Land Conservation and Development Notice of Adopted AmendmentThe attached proposed amendment is the Central Point Transportation System Plan (TSP) which will be an element of the updated Central Point ...
Central Point (Or.)
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The p.M292T NDUFS2 mutation causes complex I-deficient Leigh syndrome in multiple families [PDF]
, 2010 Isolated complex I deficiency is the most frequently observed oxidative phosphorylation defect in children with mitochondrial disease, leading to a diverse range of clinical presentations, including Leigh syndrome.
Mazhor Al-Dosary +35 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source