Results 61 to 70 of about 6,527,208 (145)

Novel Mutations in K13 Propeller Gene of Artemisinin-Resistant Plasmodium falciparum

Emerging Infectious Diseases, 2015
We looked for mutations in the Plasmodium falciparum K13 propeller gene of an artemisinin-resistant parasite on islands in Lake Victoria, Kenya, where transmission in 2012–2013 was high. The 4 new types of nonsynonymous, and 5 of synonymous, mutations we
Rie Isozumi, Haruki Uemura, Isao Kimata, Yoshio Ichinose, John Logedi, Ahmeddin H. Omar, Akira Kaneko   +6 more
doaj   +1 more source

Clinical effect of point mutations in myelodysplastic syndromes.

New England Journal of Medicine, 2011
BACKGROUND Myelodysplastic syndromes are clinically heterogeneous disorders characterized by clonal hematopoiesis, impaired differentiation, peripheral-blood cytopenias, and a risk of progression to acute myeloid leukemia. Somatic mutations may influence
R. Bejar, K. Stevenson, O. Abdel-Wahab, N. Galili, B. Nilsson, G. Garcia-Manero, H. Kantarjian, A. Raza, R. Levine, D. Neuberg, B. Ebert   +10 more
semanticscholar   +1 more source

Compound heterozygosity for a Wolman mutation is frequent among patients with cholesteryl ester storage disease

Journal of Lipid Research, 2000
Cholesteryl ester storage disease and Wolman disease are rare autosomal recessive lipoprotein-processing disorders caused by mutations in the gene encoding human lysosomal acid lipase.
Peter Lohse, Sylke Maas, Pia Lohse, Milan Elleder, Jean M. Kirk, Guy T.N. Besley, Dietrich Seidel   +6 more
doaj  

Taqman-MGB nanoPCR for Highly Specific Detection of Single-Base Mutations

International Journal of Nanomedicine, 2021
Zhenrui Xue,1– 3,* Minli You,2,3,* Ping Peng,1– 3,* Haoyang Tong,2,3 Wanghong He,2– 4 Ang Li,4 Ping Mao,1– 3 Ting Xu,1 Feng Xu,2,3 Chunyan Yao1 1Department of Transfusion Medicine, Southwest Hospital, Third Military Medical ...
Xue Z, You M, Peng P, Tong H, He W, Li A, Mao P, Xu T, Xu F, Yao C   +9 more
doaj  

Development of herbicide resistant crops through induced mutations

Advancements in Life Sciences, 2015
Herbicide resistance is an innate characteristic of crop plants. It enables them to survive and propagate even in the presence of lethal doses of herbicides in the surroundings. Genetic tolerance in crops towards herbicides may have several benefits.
Muhammad Rizwan, Sajjad Akhtar, Muhammad Aslam, Muhammad Jawad Asghar   +3 more
doaj  

Repeat-Induced Point Mutation and Other Genome Defense Mechanisms in Fungi

Microbiology spectrum, 2017
Eugene Gladyshev
semanticscholar   +1 more source

Immunological Phenotyping of Mice with a Point Mutation in Cdk4. [PDF]

Biomedicines, 2023
Yabas M, Hoyne GF.
europepmc   +1 more source

The F204S mutation in adrenodoxin oxidoreductase drives salinomycin resistance in Eimeria tenella

Veterinary Research
Salinomycin is a polyether ionophore widely used for the treatment of coccidiosis in poultry. However, the emergence of coccidia strains resistant to salinomycin presents challenges for control efforts, and the mechanisms underlying this resistance in ...
Pei Sun, Chaoyue Wang, Fujie Xie, Linlin Chen, Yuanyuan Zhang, Xinming Tang, Dandan Hu, Yang Gao, Ning Zhang, Zhenkai Hao, Yonglan Yu, Jingxia Suo, Xun Suo, Xianyong Liu   +13 more
doaj   +1 more source

Production of Gene‐Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation

Stem Cells, 2015
Xiaosong Huang, Ying Wang, Wei Yan, Cory J. Smith, Zhaohui Ye, Jing Wang, Yongxing Gao, L. Mendelsohn, Linzhao Cheng   +8 more
semanticscholar   +1 more source

Point mutation impairs centromeric CENH3 loading and induces haploid plants

Proceedings of the National Academy of Sciences of the United States of America, 2015
Raheleh Karimi-Ashtiyani, Takayoshi Ishii, M. Niessen, N. Stein, Stefan Heckmann, M. Gurushidze, A. Banaei-Moghaddam, J. Fuchs, V. Schubert, Kerstin Koch, Oda Weiss, D. Demidov, Klaus Schmidt, J. Kumlehn, A. Houben   +14 more
semanticscholar   +1 more source