Results 131 to 140 of about 859,907 (314)
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Polar vortex weakening and its impact on surface temperature in recent decades [PDF]
The stratospheric polar vortex (SPV) weakening is linked to surface circulation changes. This study employs statistical analysis using reanalysis data to compare the anomalous SPV behaviour in the Northern (NH) and Southern (SH) hemispheres and its ...
Kim, Seong-Joong, Choi, Hyesun
core +1 more source
Princess Elisabeth Antarctica: an International Polar Year outreach and media success story [PDF]
One of the priorities of the fourth International Polar Year (IPY) was to increase awareness of the polar regions and polar science among the general public through education, communication and other forms of outreach.
Cheek, Joseph +5 more
core +1 more source
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Review of the book: T. Kue Young (senior ed.) and Rajiv Rawat, Winifred Dallmann, Susan Chatwood and Peter Bjerregaard (eds.), Circumpolar Health Atlas (Toronto: University of Toronto Press, 2012)
Rachael L. Johnstone
doaj
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Neutron Polarizers Based on Polarized 3He [PDF]
The goal of this work, which is a collaborative effort between Indiana University, NIST, and Hamilton College, is to extend the technique of polarized neutron scattering into new domains by the development and application of polarized 3He-based neutron spin filters.
openaire +4 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Ecologists and physiologists have always been interested in organisms living in extreme environments because of the light they shed on fundamental problems, and the general public has long been fascinated by animals living in climates so inhospitable ...
Clarke, Andrew
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source

