Results 121 to 130 of about 859,907 (314)
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
The polar bear Ursus maritimus feeding in a seabird colony in Frans Josef Land [PDF]
During the second half of August 1992 polar bears were observed feeding intensively in the little auk Alle alle colony on Rubini Rock, Hooker Island, Frans Josef Land. They dug out nests eating eggs, chicks and adult birds. Their activity results in both
Lech Stempniewicz, Stempniewicz, Lech
core +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Polar Research evolves, and Norway and the IPY
March marks the start of the International Polar Year (IPY) and I am very pleased to announce on this occasion that we’ve joined hands with Blackwell Publishing, which will henceforth publish the journal while editorial control remains with the editorial
Goldman, Helle V.
core +1 more source
No abstract available.(Published: 9 May 2016)Citation: Polar Research 2016, 35, 31998,http://dx.doi.org/10.3402/polar.v35 ...
Goldman, Helle
core +1 more source
Le Paris des Aventures extraordinaires d’Adèle Blanc-Sec de Jacques Tardi
Piece of art, space and society are here approached in a relational perspective which focuses on the links they entertain. More precisely, the question of the city representation in the comic-book concerns geography insomuch as this artistic genre ...
Géraldine Molina
doaj +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Axel Anderson, Nikoloz Pkhakadze
openaire +3 more sources
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Revisiting perceptions and evolving culture: a community dialogue on women in polar research [PDF]
Women have made outstanding contributions to polar research in recent decades, though full engagement may be hindered by persistent inequities, including notably the prevalence of workplace harassment.
Seag, M. +7 more
core +1 more source

