Results 101 to 110 of about 1,833,092 (287)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Les femmes et le polar italien. Les trois romans policiers de Nicoletta Vallorani
Italies, 1999 Dès ses trois premiers romans, Nicoletta Vallorani (née en 1959) se consacre sciemment à la révision des règles du roman policier et à sa contamination, convaincue que « la littérature de genre offre la plus grande liberté de détruire les règles, d ...
Claudio Milanesi
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
What does the fox say? Arctic fox vocalization and associated den behaviours
Polar ResearchFoxes (Vulpes spp.) are small, solitary canids with relatively low social complexity compared to more gregarious canids, such as wolves and dogs. They are, therefore, expected to have a relatively simple vocal repertoire, with limited low-intensity ...
Kayla J. Buhler +3 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Apuntes sobre mestizaje e hibridez: los riesgos de la metáfora
Kipus: Revista Andina de Letras y Estudios CulturalesArchivo histórico de Kipus: Revista Andina de Letras y Estudios Culturales, 1997. Esta información es parte del repositorio institucional UASB-Digital, de la Universidad Andina Simón Bolívar, Sede Ecuador.
Antonio Cornejo Polar
doaj
« Bon flic » : quelques éléments sur l’image de la police dans le polar français contemporain
BelphégorL’intérêt de la critique littéraire pour le roman noir fait parfois oublier que le polar est aussi, historiquement, une littérature de police. À l’heure où la question policière nourrit mécontentements et débats en France, où les conditions d’une police ...
Lucie Amir
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Le Paris des Aventures extraordinaires d’Adèle Blanc-Sec de Jacques Tardi
Géographie et Cultures, 2007 Piece of art, space and society are here approached in a relational perspective which focuses on the links they entertain. More precisely, the question of the city representation in the comic-book concerns geography insomuch as this artistic genre ...
Géraldine Molina
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source