Results 91 to 100 of about 859,907 (314)
Cell polarity: Par for the polar course [PDF]
Current Biology, 1997 The nematode PAR-1 gene is required for asymmetric cell divisions during development. Recently identified mammalian Par-1 homologues are kinases that phosphorylate microtubule-associated proteins; their overexpression disrupts the microtubule cytoskeleton, and alters cellular structure and organization.
Nelson, W.James, Grindstaff, Kent K.
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Light and productivity of phytoplankton in polar marine ecosystems: a physiological view [PDF]
, 1991 This study deals with the modeling of photosynthesis and growth of polar phytoplankton and variations in relevant parameters. Polar regions are characterised by low sun elevations (< 40?50°), extreme seasonal variations in irradiance and day length, and ...
Slagstad, Dag, Sakshaug, Egil
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Open Access Data in Polar and Cryospheric Remote Sensing
Remote Sensing, 2014 This paper aims to introduce the main types and sources of remotely sensed data that are freely available and have cryospheric applications. We describe aerial and satellite photography, satellite-borne visible, near-infrared and thermal infrared sensors,
Allen Pope +3 more
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Regional polar warming linked to poleward moisture transport variability
Environmental Research: Climate, 2023 Polar warming, ice melt and strong precipitation events are strongly affected by episodic poleward advection of warm and moist air (Woods and Caballero 2016 J. Clim. 29 4473–85; Wille et al 2019 Nat. Geosci.
Richard Bintanja +2 more
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Interleaved Polar (I-Polar) Codes [PDF]
IEEE Transactions on Information Theory, 2020 31 pages, 12 ...
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
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A “radically new method”: balloon buoy communications of the Baldwin–Ziegler Polar Expedition, Franz Josef Land, June 1902 [PDF]
, 2008 The history of lighter-than-air operations in the Arctic between 1896 and 1930 has focused almost exclusively upon four expeditions. These are the balloon voyage of the Swede Salomon Andrée in 1896–97, and the dirigible expeditions of the American Walter
Capelotti, P.J.
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Sustainable Tourism and Natural Resource Conservation in the Polar Regions: An Editorial
Resources, 2017 This editorial provides an introduction to the special issue of Resources on Sustainable Tourism and Natural Resource Conservation in the Polar Regions, which proceeds the fifth bi-annual conference of the International Polar Tourism Research Network ...
Edward Huijbens, Machiel Lamers
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