Results 111 to 120 of about 859,907 (314)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

What does the fox say? Arctic fox vocalization and associated den behaviours

Polar Research
Foxes (Vulpes spp.) are small, solitary canids with relatively low social complexity compared to more gregarious canids, such as wolves and dogs. They are, therefore, expected to have a relatively simple vocal repertoire, with limited low-intensity ...
Kayla J. Buhler, Gustaf Samelius, Ray Alisauskas, Emily Jenkins   +3 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Apuntes sobre mestizaje e hibridez: los riesgos de la metáfora

Kipus: Revista Andina de Letras y Estudios Culturales
Archivo histórico de Kipus: Revista Andina de Letras y Estudios Culturales, 1997. Esta información es parte del repositorio institucional UASB-Digital, de la Universidad Andina Simón Bolívar, Sede Ecuador.
Antonio Cornejo Polar
doaj  

« Bon flic » : quelques éléments sur l’image de la police dans le polar français contemporain

Belphégor
L’intérêt de la critique littéraire pour le roman noir fait parfois oublier que le polar est aussi, historiquement, une littérature de police. À l’heure où la question policière nourrit mécontentements et débats en France, où les conditions d’une police ...
Lucie Amir
doaj   +1 more source

XIV.—Polar and non-polar valency [PDF]

J. Chem. Soc., Trans., 1919
n ...
openaire   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Prevalence of Trichinella sp. in polar bears (Ursus maritimus) from northeastern Greenland [PDF]

, 1990
The occurrence of infections with Trichinella sp. in polar bears (Ursus maritimus) from northeastern Greenland has been studied by examination of muscle samples, mainly diaphragm, from 38 animals shot during the period 1983-1987.
Born, E. W., Henriksen, Sv. Aa.
core   +1 more source

Les femmes et le polar italien. Les trois romans policiers de Nicoletta Vallorani

Italies, 1999
Dès ses trois premiers romans, Nicoletta Vallorani (née en 1959) se consacre sciemment à la révision des règles du roman policier et à sa contamination, convaincue que « la littérature de genre offre la plus grande liberté de détruire les règles, d ...
Claudio Milanesi
doaj   +1 more source