Results 41 to 50 of about 19,222 (246)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Efficacy of deterrents for mitigating human‐polar bear conflict in northern Alaska
Wildlife Society BulletinA warming climate is negatively affecting Arctic species that rely on sea ice to perform their life history activities. Changing sea ice dynamics have led polar bears in many subpopulations to spend more time on land, increasing the potential for human ...
Susanne Miller +5 more
doaj +1 more source
The numbers of ringed seals (Phoca hispida) in Baffin Bay and associated waters
NAMMCO Scientific Publications, 1998 The size of the population of ringed seals (Phoca hispida) inhabiting Baffin Bay and associated waters was estimated by two methods. An approximate model of the energetics of the polar bear (Ursus maritimus) estimated an energetic need of about 16,000 MJ/
Michael C S Kingsley
doaj +1 more source
The Role of Satellite Telemetry Data in 21st Century Conservation of Polar Bears (Ursus maritimus)
Frontiers in Marine Science, 2022 Satellite telemetry (ST) has played a critical role in the management and conservation of polar bears (Ursus maritimus) over the last 50 years. ST data provide biological information relevant to subpopulation delineation, movements, habitat use, maternal
Kristin L. Laidre +15 more
doaj +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
FACETS, 2023 Wildlife conservation is informed by detailed understanding of species demographics, habitat use, and interactions with environmental drivers. Challenges to collecting this information, particularly in remote places and on widely ranging species, can ...
Alexandra Langwieder +10 more
doaj +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Polar bear attack on a juvenile narwhal
Fauna Norvegica, 1990 A juvenile female narwhal Monodon monoceros landed at Pond Inlet had several sets of scratches on the posterior part of the body. They were probably made by a polar bear Ursus maritimus in the course of an unsuccessful attack.
Michael C.S. Kingsley
doaj +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Polar Bear Harvest Patterns Across the Circumpolar Arctic
Frontiers in Conservation Science, 2022 Wildlife harvest remains a conservation concern for many species and assessing patterns of harvest can provide insights on sustainability and inform management. Polar bears (Ursus maritimus) are harvested over a large part of their range by local people.
Dag Vongraven +4 more
doaj +1 more source