Results 71 to 80 of about 34,517 (262)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Reverse Convolutional Precoding of Polar Codes: Design, Analysis, and Decoding Algorithms

open access: yesIEEE Open Journal of the Communications Society
Convolutionally precoded polar codes known as polarization-adjusted convolutional (PAC) codes are a promising variant of polar codes for short block lengths.
Xinyi Gu, Mohammad Rowshan, Jinhong Yuan
doaj   +1 more source

Scaling Analysis of Multilevel Polar Coded Modulation

open access: yesIEEE Access, 2019
In this paper, we analyze and prove the capacity-achieving property of the equivalent asymmetric channels of multilevel polar-coded modulation in view of the scaling assuming regime, which employ some techniques of symmetric channels.
Kun Zhao   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Error-Aware SCFlip Decoding of Polar Codes

open access: yesIEEE Access, 2020
The successive-cancellation flip (SCFlip) decoder and its variants provide a significant coding gain with the average complexity practically identical to that of the successive cancellation (SC) decoder in a wide range of signal-to-noise ratios (SNRs ...
Daeyeol Yang, Kyeongcheol Yang
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

On Polar Coding with Feedback

open access: yesCoRR
7 pages, 7 figures and 2 tables; A short version will be submitted to IEEE for possible ...
Ling Liu 0003   +3 more
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Multilevel polar-coded modulation [PDF]

open access: yes2013 IEEE International Symposium on Information Theory, 2013
A framework is proposed that allows for a joint description and optimization of both binary polar coding and the multilevel coding (MLC) approach for $2^m$-ary digital pulse-amplitude modulation (PAM). The conceptual equivalence of polar coding and multilevel coding is pointed out in detail. Based on a novel characterization of the channel polarization
Mathis Seidl   +3 more
openaire   +2 more sources

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